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약물요법으로 약물방출 스텐트 시술 후 재협착을 더 줄일 수 있나?
한규록 ( Kyoo Rok Han ) 대한내과학회 2008 대한내과학회지 Vol.74 No.4
Until now restenosis is one of the most important issues after stent implantation. Use of systemic drug therapy to inhibit post-stent restenosis has been largely unsuccessful. Drug-eluting stents (DES) have been shown to significantly reduce restenosis after percutaneous coronary intervention. However we still experience lots of problems associated with restenosis even after DES implantation. Recently some clinical trials have suggested that cilostazol reduces intimal hyperplasia and lowers restenosis after bare metal stents (BMS) implantation. It is uncertain that cilostazol can also reduce restenosis after DES implantation. We need more large clinical trials to elucidate the efficacy of cilostazol on restenosis after DES implantation.(Korean J Med 74:366-367, 2008)
인공삼첨판막의 혈전에 의한 삼첨판막 협착증의 임상상과 치료
한규록(Kyoo Rok Han),송종민(Jong Min Song),최성주(Sung Joo Choi),한기훈(Ki Hoon Han),박선수(Sun Soo Park),오병희(Byung Hee Oh),이명묵(Myoung Mook Lee),박영배(Young Bae Park),최윤식(Yun Shik Choi),서정돈(Jung Don Seo),노정일(Chung Il 대한내과학회 1994 대한내과학회지 Vol.46 No.4
N/A Background: Thrombosis of prosthetic valve occurs more frequently in the mechanical prosthetic valve than tissue valve and more frequently in right-side heart than left-side heart. This study shows the clinical characteristics and treatment of bileaflet prosthetic valve thrombosis in the tricuspid position. Methods: Patients with bileaflet prosthetic valve in tricuspid position were followed till clinically significant tricuspid stenosis due to thrombosis develops. Five patients had clinically significant thrombotic tricuspid stenosis. Diagnosis was based on history taking, physical examaination, echocardiograpy and cinefluoroscopy. Results: Anticoagulation therapy was inadequate in 4 of 5 patients. Prosthetic valve replacement was undertaken in one patient and four patients were treated with thrombolytic therapy using urokinase. Three patients among 4 patients managed with thrombolytic therapy were successfully treated. There was no serious complication. Cinefluoroscopy and echocardiography were useful in diagnosis and evaluation of the thrombolysis. Conclusions: Thrombolytic therapy is useful as an initial treatment of thrombosed tricuspid prosthetic valve stenosis without major complications.
장재식,한규록,문건웅,전동운,신동호,김정선,박덕우,강현재,김주한,배장환,허승호,김병옥,최동훈,권현철,김효수 대한심장학회 2017 Korean Circulation Journal Vol.47 No.3
Background and Objectives: Although several multicenter registries have evaluated percutaneous coronary intervention (PCI) procedures in Korea, those databases have been limited by non-standardized data collection and lack of uniform reporting methods. We aimed to collect and report data from a standardized database to analyze PCI procedures throughout the country. Materials and Methods: Both clinical and procedural data, as well as clinical outcomes data during hospital stay, were collected based on case report forms that used a standard set of 54 data elements. This report is based on 2014 Korean PCI registry cohort data. Results: A total of 92 hospitals offered data on 44967 PCI procedures. The median age was 66.0 interquartile range 57.0-74.0 years, and 70.3% were men. Thirty-eight percent of patients presented with acute myocardial infarction and one-third of all PCI procedures were performed in an urgent or emergency setting. Non-invasive stress tests were performed in 13.9% of cases, while coronary computed tomography angiography was used in 13.7% of cases prior to PCI. Radial artery access was used in 56.1% of all PCI procedures. Devices that used PCI included drug-eluting stent, plain old balloon angioplasty, drug-eluting balloon, and bare-metal stent (around 91%, 19%, 6%, and 1% of all procedures, respectively). The incidences of in-hospital death, non-fatal myocardial infarction, and stroke were 2.3%, 1.6%, and 0.2%, respectively. Conclusion: These data may provide an overview of the current PCI practices and in-hospital outcomes in Korea and could be used as a foundation for developing treatment guidelines and nationwide clinical research.