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- 저자 : 최의경(Eui Kyung Choi) (검색결과 2 건)
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갑상샘 저하증으로 진단된 극소저체중출생아에서의 생후 초기 의 장관영양 식이양상 비교
최의경 ( Eui Kyung Choi ),이현승 ( Hyeon Seung Lee ),이은희 ( Eun Hee Lee ),김세연 ( Sae Yun Kim ),이병국 ( Byoung Kook Lee ),정영화 ( Young Hwa Jung ),허주선 ( Ju Sun Heo ),신승한 ( Seung Han Shin ),김이경 ( Ee Kyung Kim ),김한석 대한주산의학회 2015 Perinatology Vol.26 No.1
Purpose: We investigated the effects of hypothyroidism on feeding advancement in very low birth weight infants (VLBW). Methods: This study was a retrospective case-control study of 14 very low birth weight infants (VLBWIs) diagnosed with hypothyroidism and other 14 infants were recruited as age- and weight-matched controls without hypothyroidism or hypothyroxinemia in Seoul National University Children’s Hospital between January 2007 and August 2009. We examined whether these infants gained weight more, achieved full-volume enteral feedings sooner, had fewer episodes of increased pre-gavage residuals, and had fewer days of parenteral nutrition. Results: Until full enteral feeding (120 mL/kg/day) was not statistically significant between the groups. In the hypothyroidism group, during the first 14 days after birth, the volume of feeding was smaller [14.7 (0.5-84.0) mL/ kg/day, P=0.041], the episodes of increased pre-gavage residuals were frequently observed [16.7 (0.2-78) times, P=0.036], and the duration of central line was significantly longer [18 (10-50) days, P=0.018]. In hypothyroidism group, mean day at first L-thyroxine supplementation was 24.2±10.2 days after birth. L-thyroxine administration boosted thyroid function for hypothyroidism infants, helped them tolerate a larger amount of enteral feeding [from 89.5 (2.9-160.8) to 146.9 (31.8-178.8) mL/kg/day, P=0.002] and decreased episodes of excessive gastric residuals [from 5.5 (0-41.6) to 0 (0-44) time, P=0.026]. However, no more weight gain was statistically found. Conclusion: In VLBW infants, hypothyroidism may induce feeding intolerance. L-thyroxine supplementation was effective in feeding advancement on preterm infants with hypothyroidism.
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이경은(Kyoung Eun Lee),우정희(Jung Hee Woo),신정희(Jung Hee Shin),최의경(Eui Kyung Choi),최성은(Sung Eun Choi),김지연(Ji Yeon Kim),최병민(Byung Min Choi),은소희(So-Hee Eun) 대한소아신경학회 2018 대한소아신경학회지 Vol.26 No.3
Purpose: To identify the significance of the 12-month developmental assessment in high-risk neonates by comparing their 12 month and later childhood development. Methods: We retrospectively reviewed the records of high risk neonates admitted to neonatal intensive care units of Korea University Ansan Hospital for ten years. Data of 146 patients, who underwent the Bayley test at 12 months of age and retook the same test at 24-36 months, was analyzed. Changes in mental developmental index (MDI) and psychomotor developmental index (PDI) were assessed and <85 scores of indices were defined as abnormal. Results: At 12 months of age, 35 (24.0%) had normal development, 45(30.8%) had psychomotor developmental delay (MDI≥85, PDI<85), 7(4.8%) had mental developmental delay (MDI<85, PDI≥85), and 59(40.4%) had global delay (MDI & PDI <85). At 24–36 months of age, 52(35.6%) had normal development, 10(6.8%) had mental delay, 16(11.0%) had psychomotor delay, and 68(46.6%) had global delay. Out of 35 patients with normal development at 12 months, 27(77.1%) showed normal development after that, and 46(78.0%) of 59 patients with global delay showed a global delay. All 7 patients who had delayed mental development at 12 months showed global delay at 24–36 months of age (P<0.01). The 12-month development of high-risk neonates was associated with later developmental status. Conclusion: Considering the importance of early intervention for delayed development, the 12-month Bayley test of high-risk neonates may be useful for prediction of later developmental progress.
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