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김영,조방환,유장신,최계두,이동화,강득용,박희숙 순천향대학교 1981 논문집 Vol.4 No.3
HMR is a clinicopathologic syndrome charactetized by its acute onset and relent1ess progression to death within a few mouths, and first describes by Scott Robb-Smith in 1939. The clinical features include fever, malaise weakness, weight loss, lymphadenopathy. hepatosplenomegaly progressive pancytopenia, Jaundice, purpura occationaly papulic skineruptions or tumors. Cardinal pathologic featurea are systemized proliferation of atypical neoplastic histiocytes. We have a case manifested by aplastic anemia progressively developed in skin Lesion 6 months later, and finally confirmed with HMR by repeated bone marrow study and skin biopsy.