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Shang Zhao(조상),Seoksoon Lee(이석순) 항공우주시스템공학회 2019 항공우주시스템공학회 학술대회 발표집 Vol.2019 No.5
It is reported in previous articles that these nanoparticles will produce substantial heat that typically increases the tumor temperature, which can treat cancer cells, and another major potential of magnetic nanoparticles is the ability to combine heat and drug release for cancer treatment. However, insufficient AC induction heating power at a biological safe range of AC magnetic field and highly required biocompatibility of superparamagnetic nanoparticle hyperthermia agents have still remained as critical challenges for successful clinical hyperthermia applications. In this work, two different types nanoparticles (Fe3O4, Fe2O3) were modified by whey protein isolation (WPI), these biomodified superparamagnetic nanoparticles (WPI-SNPs) display excellent stability in different conditions and have a spherical shape with a diameter around between 40nm-100nm. Doxorubicin (DOX) was then successfully loaded into WPI-SNPs with a desirable loading content of 12%. In vitro and in vivo magnetic hyperthermia studies using WPI-SNPs nanofluids are conducted to estimate bio-availability and bio-feasibility, and experimental results prove WPI-SNPs nanofluids which show promising hyperthermia effects to completely treat the tumors.
남광식(Kwang Sik Nam),최진규(Jin Gyu Choi),조상(Shang Zhao),김재기(Jea Ki Kim),최호민(Ho Min Choi),이석순(Seok Soon Lee) Korean Society for Precision Engineering 2016 한국정밀공학회지 Vol.33 No.4
The fiber optical temperature sensing device was developed by using a Fiber Bragg Grading (FBG) sensor and a linear transmittance optical filter. The temperature change causes change in the FBG sensor reflectance wavelength and the reflectance wavelength from FBG sensor is transmitted to a linear transmittance filter so that the optical signal value is determined by the wavelength. The temperature can be measured by the optical signal value by passing FBG reflectance wavelength to the linear transmittance filter. Using the developed system, temperature ranges from 10℃ to 50℃ were measured and the measured data were almost linear.
최진규(Jin-Gyu Choi),이동욱(Dong-Wook Lee),박민혁(Min-Hyeok Park),남광식(Kwang-Sik Nam),조상(Zhao Shang),이석순(Seok-Soon Lee) 대한기계학회 2014 대한기계학회 춘추학술대회 Vol.2014 No.5
Roll Forming technology has a problem forming components by depending on only experiences without accurate data in actual field. To solve the problem, its necessary to analyze FEM of Roll Forming process. Main function of Roll Forming Tool is continuous bending work of materials thickness with few changes. Therefore, this research did a comparative study between FEM result of aluminum plate formed by Roll_Forming Tool and its experiment. FEM result shows that plastic deformation of aluminum plate can be practicable and it is similar to the result of thickness experiment. In addition, design of automatic roll forming machine helped forming process.