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정수민,최재현,박제원,Chung, Su-min,Choi, Jae-hyun,Park, Jea-won 한국정보통신학회 2016 한국정보통신학회논문지 Vol.20 No.7
정보기술인 인터넷과 하드웨어기술의 급진적인 발전에 따라 모든 사물에 인터넷을 연결하여 사물끼리 또는 사물과 사람사이에 의사소통을 하는 사물인터넷의 보급률과 이용률이 지속적으로 증가하고 있다. 이미 스마트 워치를 중심으로 한차례 사물인터넷 돌풍이 일어난 상태이며, 냉장고, 세탁기, 전구, 스위치 등 집안의 모든 사물을 스마트폰으로 조작하는 스마트 홈 킷이 현실화되고 있다. 각각의 디바이스는 자체적인 기능 구현이 가능하고, 중심 역할을 처리하는 허브를 통해 좀 더 지능화되고 협력적인 기능을 제공한다. 하지만 사물인터넷 디바이스의 양이 급증하는 것에 비해 사물인터넷 기반 소프트웨어의 품질 평가에 관한 연구는 매우 부족하여 그 품질기준이 명확하지 않다. 특히 IoT 기반 SW는 사물인터넷 디바이스를 통해 활용되기에 이동성과 휴대성, 실시간 접근성과 같은 특징과 디바이스라는 것에 대한 하드웨어적인 특징을 포괄하고 있기 때문에 포함하기에 일반적인 소프트웨어와는 차별화된 품질기준과 평가모델이 필요하다. 본 논문에서는 이러한 필요성에 따라 사물인터넷 소프트웨어 평가모델을 제안하고자 한다. 국제표준 ISO/IEC 25000의 품질 특성을 바탕으로 본 논문의 평가 모델을 제시하고, 시나리오 기반 사례연구를 수행하여 검증을 하였다. As Internet, and hardware technology are in rapid process, using rate and penetration rate of Internet of Things are increasing. Internet of Things is the physical objects with network which embedded with electronics, software, sensors, and network. Smart Home-kit to operate refrigerators, washing machines, light bulbs, and such internet of things by a smartphone has been realized. However, it is difficult to use a good quality of software based on IoT. It is because that the study related to quality evaluation of software based on IoT is deficient compared with increase amount of IoT devices. Software based on IoT includes mobility, transportability, real time accessibility and hardware characteristics. Therefore, it is necessary to have differentiated quality standards and quality model. Software quality evaluation model for IoT is proposed to satisfy these needs. Evaluation model is mapped by characteristics of IoT software based on ISO/IEC 25000's quality characteristics. Scenario based studies were applied to quality model for verification.
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사람 말초혈액 단핵세포에서 녹두 렉틴의 사이토카인 생성효과
전경희,안몽기,정수민,최경민,이승호,정시련,Jeune, Kyung-Hee,An, Mong-Gi,Jung, Su-Min,Choi, Kyung-Min,Lee, Seung-Ho,Chung, See-Ryun 한국생약학회 1999 생약학회지 Vol.30 No.4
New lectins have been isolated and purified from mung bean (Phaseolus radiatus) through physiological saline extraction, ammonium sulfate salt fractionation and column chromatographies. Ion exchanger were eluted by linear salt gradient and then further purified through gel filtration. Thus obtained lectin named as MBL. The gene expressions of 5 cytokines (IL-1, IL-2, IL-6, $TNF-{\aphpa}$ and $IFN-{\gamma}$) from human peripheral blood mononuclear cells (PBMC) stimulated with MBL were investigated by using reverse transcription polymerase chain reaction (RT-PCR). PBMC ($1{\times}106$ cells/ml) isolated from healthy volunteers were stimulated with lectins (4 mg/ml) for various time intervals (1 to 96 hrs). After each of the various stimulated times, total RNA was isolated and assessed for different cytokines mRNA by RT-PCR. The mRNA encoding IL-1, IL-2 were detected continuously from 1 to 20 hrs, and IL-6 was detected up to 24 hrs. But the mRNA encoding $IFN-{\gamma}$ and $TNF-{\alpha}$ were detected to 8 hours only and showed short time response compared with other cytokines. The significant expression of all cytokines mRNA were observed at 4 hrs. These results suggested that MBL, as inducer of cytokines could elicit detectable cytokine mRNA from PBMC.
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정시련(See Ryun Chung),정수민(Su Min Chung),이승호(Seung Ho Lee),전경희(Kyung Hee Jeune) 대한약학회 1996 약학회지 Vol.40 No.4
The erythrocytes agglutination test was applied to the common korean plants for lectin activity screening by using human blood. During the four years, 108 species from 46 families of floras were collected, identified and subjected to the test after being divided into several different parts. Only 13 species demonstrated strong lectin activities. Meanwhile 66 species did not shown any agglutination. All others were observed as having low activity or as having hemolytic constituents.
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정시련,정수민,이승호,전경희 영남대학교 약품개발연구소 1996 영남대학교 약품개발연구소 연구업적집 Vol.6 No.-
The erythrocytes agglutination test was applied to the common korean plants for lectin activity screening by using human blood. During the four years, 108 species from 46 families of floras were collected, identified and subjected to the test after dividing into several different parts. Only 13 species demonstrated strong lectin activities. Meanwhile 66 species did not shown any agglutination. All others were observed as low activity or as having hemolytic constituents.
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사람 말초혈액 단핵세포에서 녹두 렉틴의 사이토카인 생성효과
전경희,안몽기,정수민,최경민,이승호,정시련 영남대학교 약품개발연구소 2000 영남대학교 약품개발연구소 연구업적집 Vol.10 No.-
New lectins have been isolated and purified from mung bean(Phaseolus radiatus) through physiological saline extraction, ammonium sulfate salt fractionation and column chro-matographies. Ion exchanger were eluted by linear salt gradient and then further purified through gel filtration. Thus obtained lectin named as MBL. The gene expressions of 5 cytokines(IL-1, IL-2, IL-6, TNF-α and IFN-?) from human peripheral blood mononuclear cells(PBMC) stimulated with MBL were investigated by using reverse transcription polymerase chain reaction(RT-PCR). PBMC(1×106cells/㎖) isolated from healthy volunteers were stimulated with lectins(4㎎/㎖) for various time intervals(1 to 96 hrs). After each of the various stimulated times, total RNA was isolated and assessed for different cytokines mRNA by RT-PCR. The mRNA encoding IL-1, IL-2 were detected continuously from 1 to 20 hrs, and IL-6 was detected up to 24 hrs. But the mRNA encoding IFN-r and TNF-α were detected to 8 hours only and showed short time response com-pared with other cytokines. The significant expression of all cytokines mRNA were observed at 4 hrs. These results suggested that MBL, as inducer of cytokines could elicit detectable cytokine mRNA from PBMC.
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