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전용석(Yong Suk Chun),원석규(Seok Kyu Won),이명의( 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.1
The presence of an enlarged transverse process on one or both sides of the last lumbar vertebra is a common congenital anomaly of the lumbar vertebra. It is thought to be a genetic or developmental anatomical variant. The first reported assimilation of the fifth lumbar vertebra into the sacrum associated with low back pain was in 1917 by Bertolotti. However, clinical significance of lumbosacral transitional vertebra has not been fully considered due to lack of scientific investigations dealing with it. We experienced a case of symptomatic lumbosacral transitional vertebra during management of low back pain. Low back pain was relieved after infiltration of local anesthetics and steroid into the false joint of lumbosacral transitional vertebra. This result may possibly indicate a significant correlation between low back pain and lumbosacral transitional vertebra.
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경막외강내 스테로이드 투여후 관찰된 혈중 Prolactin 증가와 유즙 분비
원석규(Seok Kyu Won),전용석(Yong Suk Chun),석민호( 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.1
Epidural steroid injection have become one of the most frequently applied conservative option for the management of acute and chronic back pain. As the indications for epidural steroid injections increase so do the adverse responses associated with this procedure. This study reports the succession of 3 patients who developed galactorrhea and hyperprolactinemia after recieving an epidural steroid injection for lumbar radiculopathy and low back pain. Serum prolactin level was elevated in accordance with epidural injection of corticosteroid. We measured the serum prolactin level by immunoradiometric assay method and peak serum prolactin level at above 500, 144.2, 150.3 ng/ml respectively. Also we found the serum prolactin level decreased to nonnal values 3 wks after corticosteroid injection. Galactorrhra ceased in advance of decrease of serum prolactin level. That Hyperprolactinemia and galactorrhea can occur following epidural steroid injection, requires a much larger prospective investigation.
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담낭절제술 환자에서 0.5 % Bupivacaine 의 창상내침윤이 수술후 동통에 미치는 영향
이태영,전용석,승익상 대한마취과학회 1992 Korean Journal of Anesthesiology Vol.25 No.3
In spite of general agreement that pain relief after upper abdominal surgery is important for the reduction of postoperative morbidity, the most widely used method remains intramuscular injection of narcotics or non-opioid analgesics with their well known disadvantages of respiratory depression, nausea, vomiting and epidural anesthesia and intercostal nerve block are invasive, so do not achieve much popularity. This double-blind prospective study, 30 patients with subcostal incision performed for cholecystectomy, reeeived 20 ml of either physiologic saline or 0.5% bupivacaine by wound infiltration at the time of closure of the incision. After operation, pain score and analgesic requirements were compared at emergence and postoperative 24 hour in each group. The results were as following: 1) Mean age of control and bupivacaine group were 45.3±14.9 and 53.6±10.3 yr respectively and mean duration of anesthesia 175±63 and 145±54 minutes respectively. 2) At emergence, mean pain score was 7.7±1.7 in control an±2.6 in bupivacaine group (p $lt; 0.01), and at postoperative 24 hour, mean value of pain score was 6.8±2.1 in control and 2.31.9 in bupivacaine group(p$lt;0.01). 3) At emergence, there were 11 patients(73%) of none to mild pain, 3(20%) of moderate pain and 1(7%) of severe pain in bupivacaine group, while 0(0%), 6(40%) and 9(60%) respectively in control group. But at postoperative 24 hour, the number of patients with none to mild, moderate and severe pain were 13(87%), 2(13%) and 0(0%) in bupivacaine group and 4(27%), 3(20%) and 8(53%) in control group respectively. 4) In experimental group, patients less than 14% needed additive analgesic, and there were no side reactions in the bupivacaine group. With above results, we suggest that pouring of 0.5% bupivacaine into incisional wound, especially in cholecystectomy patients, would be a method for postoperative pain relief.
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김동환,김교상,이동호,전세웅,심재철,서정국,유희구,전용석,전종헌,김경헌 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.5
The domestic product of a non-depolarizing muscle relaxant, Metuben, was studied on its effect in rabbit. Twenty four rabbits of either sex weighing 2~3kg were divided into four groups (consisting of 6 animals each) to administer Metuben in doses of 0.05 mg/kg, O.l mg/kg, 0.2 mg/ kg and 0.4 mg/kg, respectively. All animals were anesthetized with 20% urethane 5 ml/kg given intraperitoneally and 2.5% pentothal sodium 10 mg/kg intravenously. ECG was monitored by Physio-contro1(lifepak 7)model. The animal lungs were mechanically ventilated through a tracheostomy and Shinano animal respirator set to deliver a 30 ml/kg tidal volume at 30 breaths/min. This ventilatory pattern resulted in the PaCO2 values within the range of 30-40 mmHg. Twitches of the tibialis anterior muscle were elicited at 0.1 Hz, $quot;Train of four$quot; via the peroneal branch of the sciatic nerve, and the Myotest stimulator were applied at supramaximal voltage. Twitch recording was done via Biophysiograph. Results were as follows: 1) The effect of Metuben as a dose-dependent long lasting non-depolarizing muscle relaxant was confirmed. Their relaxant effect in rabbits were quite different from man. 2) In rabbits, Metuben showed great individual differences in its effect even with the s'ame dosage. The length of muscle relaxing activity.and the occurence of recurarization after neostigmine reverse were extremely variable suggesting its safety margin is quite narrow.
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하부요로감염 및 과민성방광의 발현과 질 산도의 상관관계
이성주,유석선,홍근식,구진모,홍경표,김영준,전용석,정우식,심봉석,윤하나 이화여자대학교 의과대학 2010 EMJ (Ewha medical journal) Vol.33 No.1
Purpose:Vaginal pH change is known as one of the risk factors for recurrent lower urinary tract infection in female. The objective of this study was to analyze the correlation between lower urinary tract infection & overactive bladder revelation and vaginal pH by age group. Materials and Methods:Subjects were schizophrenic out-patients, who fufilled DSM-IV diagnostic criteria, and their families. Results:This study found a positive correlation between age and vaginal pH(p=0.000). It also found that the contraction of cystitis patients was high in older age group(p=0.035). However, vaginal pH was not a significant factor to the contraction of cystitis(p=0.258). In older age group, the number of overactive bladder patients was higher than that of younger age group(p=0.05), while vaginal pH was not a significant factor to the contraction of overactive bladder(p=0.376). Conclusion:Diseases that cause lower urinary tract symptom such as overactive bladder and recurrent cystitis increase in proportion to age. Vaginal pH also increases in proportion to age. However, vaginal pH is not a significant factor to the contraction of lower urinary tract symptom when the age is revised.
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