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태아 심박동 단기 변이도를 이용한 근사 엔트로피 측정으로 태아 긴박증 진단
최은주 ( Eun Ju Choi ),정대영 ( Dae Young Chung ),심영보 ( Young Bo Shim ),이상훈 ( Sang Hoon Yi ),유철승 ( Chul Seung Lew ),이지현 ( Ji Hyun Lee ),신종철 ( Jong Chul Shin ),안현영 ( Hyun Young Ahn ),김수평 ( Soo Pyung Kim ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.3
목적 : 근사 엔트로피 (Approximate entropy; ApEn)는 태아 심박변이 (heart rate variability; HRV) 복잡도와 규칙성의 변화를 정량화 하는 양으로 정상상태의 태아와 가사상태의 비정상 상태의 태아를 구분하고자 연구를 하였다. 연구 방법 : 컴퓨터화 된 전자식 태아 감시장치와 제대 혈액가스 검사를 시행한 76명의 산모 중 36명의 정상군과 40명의 가사군을 제대 혈액 가스값에 의해 26명의 추정 가사군과 14명의 산 Objective : The purpose of this study was to evaluate the usefulness of approximate entropy on fetal heart rate variability of electronic fetal monitoring taken during antepartum and intrapartum periods as a new diagnostic method of fetal distress. Method
천연희(Yeon Hee Cheon),김동주(Dong Joo Kim),정대영(Dae Young Chung),박경태(Kyung Tae Park),심영보(Young Bo Shim),유철승(Chul Seung Lew),이상훈(Sang Hoon Yi),신종철(Jong Chul Shin),이형근(Hyung Geun Lee),김수평(Soo Pyung Kim) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.5
N/A Objective : To evaluate the usefulness of power spectral analysis on fetal heart rate variability as a new diagnostic method of fetal distress. Study Design : Among 76 pregnant women who underwent computerized electronic fetal monitoring and cord blood gas analysis, we divided them into 3 groups, i.e.; normal fetus group (36), presumed distress group (26) and acidemic distress group (14). In order to perform linear analysis on the raw data of the fetal heart rate, after resampling, we performed Fourier transformation and investigated power distributions among very low frequency (VLF), low frequency (LF), high frequency (HF) bands, and autonomic balance (LF/HF). Results : The results of the spectral analysis showed that in normal fetus group, the difference in the distribution of power spectrums of VLF, LF and HF was significantly higher than in presumed distress group and acidemic distress group. In fetal distress, the LF and VLF value (0.0023, 0.0437) were good predictors (sensitivity 97.5%, 75.0% and specificity 86.1%, 94.4%). The LF value (0.0013) was a good predictor in fetal acidemia (sensitivity 97.5% and specificity 86.1%). Conclusions : A computerized spectral analysis of fetal heart rate variation is a good predictor of fetal distress, which is made automatically and objectively.