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최상섭 ( Sang Sup Choi ),조문재 ( Moon Jae Jho ),이경화 ( Kyung Hwa Lee ),민윤기 ( Yoon Ki Min ),오애령 ( Ae Reyoung Oh ),손진훈 ( Jin Hun Sohn ) 한국감성과학회 1998 추계학술대회 Vol.1998 No.-
This study investigated the psychological and physiological responses to the sound of car horns produced by different manufacturers. Ten female college students listened to the sound of the horns while their EEG responses on 6 sites were being measured, and rated each hom on psychological scales. Their EEG and psychological responses were investigated as to whether the responses were related to the loudness, sharpness, tonality, and roughness of the horns. The results indicated that the subjects felt more ``dominated`` as the loudness and sharpness increased, that the subjects felt more ``pleasant`` as the sharpness increased, that the subjects felt more ``dominant`` as the tonality increased, and that the subjects felt more ``aroused`` as the roughness increased. The physiological results showed that the fast alpha wave in the occipital lobe decreased in the relative power as the loudness, sharpness, and tonality increased, and that the delta wave in the occipital lobe increased and the slow alpha wave in the frontal lobe decreased in the relative power as the roughness increased.
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고속핵 자극에 의해 유발되는 통각억제에 관련되는 상행체계
손진훈,오애령 한국심리학회 한국심리학회지 생물 및 생리 Vol.4 No.1
고속핵에 대한 전기적, 화학적 자극은 열에 의해 유발되는 통각을 억제 시키는 것으로 알려져 왔다. 본 연구에서는 고속핵 자극에 의한 통각억제에 중뇌 이상의 뇌구조가 관련이 있는지, 그리고 통각억제와 이의 하행성 통로로 중요한 구조인 연수의 거대 봉선핵이 관련되어 있는지를 규명하고자 하였다. 수컷 Sprague-Dawley종을 사용하였으며, “꼬리 튀기기” 방법을 사용하여 통각 예민성을 측정하였다. 고속핵과 중뇌사이를 관상절단 하였을 때, 고속핵 자극에 의한 통각억제의 역치는 유의미하게 증가하였다. 자극역치가 거의 두배로 증가하거나, 운동효과(예컨데, 꼬리 움직임)의 부작용이 나타나는 경우는 더 이상 높은 전기자극을 하지 않았다. 중뇌의 문측을 관상절단 하였을 때는 고속핵 통각억제의 자극역치에 변화가 없었다. 거대 봉선핵 자극은 고속핵자극보다 낮은역치에서 통각억제를 유발하였으며, 거대 봉선핵 손상은 통각억제를 위한 고속핵의 자극역치를 유의미하게 증가시켰다. Electrical stimulation of the nucleus tractus solitarius(NTS) produces opioid-mediated antinociception. The NTS has extensive reciprocal connections with higher brain structures. Notable among these are connections with nucleus raphe magnus (NRM). This study sought to determine whether NTS stimulation-produced antinociception (SPA) relies on cennections with higher brain structures and/or the NRM. Male Sparague-Dawley rats were anestheuized with pentobarbital (55㎎/㎏) and mounted stereotaxic apparatus. Pain sensitivity was masureed using the tail-flick test. In the experiment 1, a stimulating electrode was positioned in the NTS and holes were drilled so that a guide cannular could be lowered into the hole Through this cannula a wire was inserted allowing coronal brain section to be made. Thresholds for SPA were determined before and after coronal sections. Sections were made rostral to the midbrain and between the NTS and midbrain. In the experiment 2, similar procedures were followed except selective electrolytic lesion (1㎃, DC, 20 sec) of the NRM were made. Transections between the NTS and midbrain significantly increased the threshold for SPA in the NTS. Cuts made rostral to the midbrain had no effect on SPA threshold, NRM lesions also increased SPA threshold. In this experiment, baseline tail-flick latencies were always increased for approximately 2 to 5 minutes after the lesion. Taken together, these results suggest that stimulation of the NTS produces antinociception via not any brain nuclei rostral to midbrain but a descending system arising in the NRM at least.
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