한방병원 산후조리센터 내 신생아의 한방적 처치에 대한 임상적 고찰

양미라,김선미,Yang, Mi-Ra,Kim, Sun-Mi 대한한방소아과학회 2004 대한한방소아과학회지 Vol.18 No.2

Objective : The aim of this study is to investigate the effects of oriental medical treatments for neonates in the Postpartum care center. Methods : This clinical study was carried out with the 186 neonates who admitted to the Postpartum Care Center of Conmaul Oriental Medicine Hospital, from November, 2003 to May, 2004. The data of sex, delivery method, gestation age, birthweight, symptoms, herbal prescription, improved condition and other treatments was collected via the medical charts. Results : Among 186 newborn babies, 48 cases had diarrhea. We used Gwakhyangjeonggi-san for 31 cases, Bulwhangumjeongnggi-san for 5 cases, compound prescription of the two for 8 cases. The effect of treatment was excellent for 25 cases, good for 11 cases, not good for 8 cases. In fever, there were 39 cases. We used Gwakhyangjeonggi-san and venesection of blood for 17 cases, only venesection of blood for 20 cases, and only Gwakhyangjeongg-isan for 3 cases. The effect of treatment was excellent for 37 cases, good for 3 cases. In cold, there were 4 cases. We used Samsoum for 1 case, Socheongryong-tang for 3 cases. The effect of treatment was excellent for 2 cases, good for 1 case, not good for 1 case. Conclusions : This study shows oriental medical treatments like acupucture, herbal medicine, and venesection of blood for neonates have significant effects. we will need further prospective studies about effects of these oriental medical treatments.

소아(小兒) 재발성(再發生) 삼출성(渗出性) 중이염(中耳炎)에서 가미형개연교탕(加味荊芥連翹湯)의 치료효과(治療效果)에 대한 임상적(臨床的) 연구(硏究)

양미라,진경선,이해자,권미원,박은정,Yang Mi-Ra,Jin Kyong-Son,Lee Hai-Ja,Kwon Mi-Won,Park Eun-Jeung 대한한방소아과학회 2001 대한한방소아과학회지 Vol.15 No.2

Otitis media with effusion(OME) is the second most common disease in childhood after upper respiratory tract infection. Antibiotic treatment and ventilation tube insertion are the common treatment. The emergence of drug-resistant streptococcus pneumoniae (DRSP) has implications for the primary care provider who treats acute otitis media(AOM) in children. OME need not be treated with antibiotics unless the effusion has been present for 3 to 4 months. Tympanostomy tubes are an effective treatment for both chronic OME and recurrent AOM. But the complications of tympanostomy tubes are serious Kamihyunggyeyungyotang is known to have antiinflmmatory and antiallergic effect. In this study, we investigated the clinical efficacy of the Kamihyunggyeyungyotang on recurrent otitis media with effusion prospectively by using pneumatoscopy, tympanogram, pure tone audiometry, and radiologic study. The patients who had treated by antibiotics was used as control. The statistical analysis was done by Mann-Whitney test and the significance was considered when the p value was less than 0.05. The general outcome was significantly higher in Kamihyunggyeyungyotang group than in antibiotic group. The recovery rate from grade 3 to 0 in pneumatoscopy was 42.5% but the control was 6%. Hearing gain was improved 71% and pnuematization was returned 70%.

욕창(褥瘡)환자를 활석분(滑石粉)으로 치료(治療)한 치험 2예

양미라,최진영,신학수,정용준,김관식,서관수,김동웅,신선호,조권일,Yang, Mi-Ra,Choi, Jin-Young,Shin, Hak-Soo,Jung, Yong-Jun,Kim, Kwan-Sik,Seo, Kwan-Soo,Kim, Dong-Woung,Shin, Sun-Ho,Cho, Gwon-Il 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.4

Pressure sore(Decubitus ulcer) is an area of ulceration and necrosis of the skin and underlying tissues occurring over the body prominence such as the sacrum, greater trochanter, scapula, lateral malleolus, thoracic spine and heels after prolonged or often repeated pressure. These days incidence of pressure sore have been increased because of the many population of the old, traffic accidents and cerebral vascular disease. But the treatment was not confirmly established. As for treatment, we used Talcum powder for 10 days in case 1 and 6 days in case 2. The patients were improved within 14 days after treatment in case 1 and 10 days in case 2.

음낭수종 환자 치험 1례

양미라,나원경,박은정,이지연,Yang, Mi-Ra,Na, Won-Gyung,Park, Eun-Jung,Lee, Ji-Yeon 대한한방소아과학회 2002 대한한방소아과학회지 Vol.16 No.1

Hydrocele is commonly found clinically and it is associated with patent processes vaginalis. The exact causes of this disease have no been proved up to now however monthly this disease disappears in twelve months after birth but some cases remain. For the treatment we do hydrocelectomy and although the rate of complications were low, sometimes the complications result in reoperations of children. Form the view of oriental medicine, hydrocele is included in susan(水疝) and this treatment originated from naekyung(內經). In this case, we got good results after treating a boy at the age of twenly-five months by bojungikitanggamibang therefor we want to annoume this.

가미형개연교탕(加味荊芥蓮翹湯)이 만성부비동염(慢性副鼻洞炎)의 비강섬모운동(鼻腔纖毛運動)에 미치는 영향(影響)

양미라,박은정,임태형,진경선,Yang, Mi-Ra,Park, Eun-Jeung,Im, Tae-Hyung,Jin, Kyong-Sun 대한한방소아과학회 2003 대한한방소아과학회지 Vol.17 No.1

Background: Delayed mucociliary clearance develops the pooling of nasal secretion in the nasal cavity and is a common cause of vicious cycle of symptoms in chronic sinusitis. mucociliary clearance depends on the ciliary activity, the rheological property of the secretion and on the interaction between cilia and the mucous blanket. Objective: To demonstrate the therapeutic effect of herbal medicine (Hyunggyeyungotang) on the mucociliary transport in the chronic sinusitis using saccharine Materials and methods: Forty patients treated in our hospital between september 2000 and september 2001 were studied. Before and after therapy group are composed of twenty patients. Kamihyunggyeyungyotang was administered mainly. We analyzed the saccharine mucociliary transport time of patients. Results: 1) In the control group, the transport time is about 13.4 minutes. 2) In chronic sinusitis before Kamihyunggyeyungotang therapy, the transport time is about 27.7 minutes. 3) In chronic sinusitis after Kamihyunggyeyungotang therapy, the transport time is about 13.8 minutes. Conclusion: Delayed mucociliary transport time in chronic sinusitis is earlier after Kamihyunggyeyungotang therapy.

쭈쭈가무시병(Tsutsugamushi disease)으로 진단된 환자를 升麻葛根湯加味方, 調中益氣湯 및 Doxycycline으로 치료한 치험 2예

양미라(Mi-Ra Yang),최진영(Jin-Young Choi),김동웅(Dong-Woung Kim) 대한한의학회 2000 대한한의학회지 Vol.21 No.4

Effect on Cryopreservation Stability of Kimchi Duruchigi Supplemented with Rubus coreanus Miquel Extract

Mi Ra Yang(양미라),Gun Ryoung No(노건영),Suk-Nam Kang(강석남),Sam Woong Kim(김삼웅),Il-Suk Kim(김일석) 한국생명과학회 2015 생명과학회지 Vol.25 No.12

본 연구는 열수 추출된 복분자 분말을 김치두루치기에 첨가한 후 저온저장에 따른 품질 안정성을 평가하기 위해 수행되었다. 복분자 추출물의 DPPH와 수퍼옥사이드 라디칼 소거 활성은 70.63%와 57.87%로 각각 비교적 높게 나타났다. 샘플은 대조구(무처리), T1 (15% 복분자 추출물), T2 (30 복분자 추출물), T3 (0.5% 아스코르빅산;양성대조구)를 첨가하여 제조하였다. 복분자 추출물 첨가 샘플은 대조구와 양성 대조구에 비교하여 저장 기간에 따라 pH는 온화하게 변화되는 것으로 나타났고, 대조구에 비교하여 보수력이 개선되었다. 육색은 대부분 시간경과가 될수록 증가되는 경향성을 보였으며, 대조구보다 더 낮은 변화의 폭을 보였다. 지질 과산화는 저장일수와 처리에 상관없이 거의 변화가 없는 것으로 나타났으며, 단백질 변패도는 대조구에 비교하여 낮은 것으로 나타났다. 관능분석 결과 T1과 T2는 대조구와 양성대조구에 비교하여 더 좋은 맛과 풍미를 가지며, 전체 기호도가 더 좋은 것으로 나타났다. 따라서 복분자 첨가 김치 두루치기는 제품의 저장 안정성을 개선하고, 제품의 기호도를 개선하는 것이 가능한 것으로 제의된다. The goal of this study was done for evaluating stability according to low-temperature storage of kimchi duruchigi supplemented with a hot water extract of Rubus coreanus Miquel (RCM). Total polyphenol and flavonoid contents in the RCM extract prepared from the hot water were detected by 293.34 μg CA/mg and 90.57 μg quecetin/mg, respectively. DPPH and superoxide radical scavenging activities of the extract were showed by relatively high values of 70.63 and 57.87%, respectively. Kimchi duruchigi was designed by control (non-treated), T1 (3% RCM extract), T2 (6% RCM extract), and T3 (0.1% ascorbic acid, a positive control). When compared with control and T3 groups, pHs of T1 and T2 groups supplemented with the RCM extract were gently changed depending on the storage time, and water holding capacities of T1 and T2 groups were improved in comparison with control group. Although meat color showed a tendency to most of increase according to the elapsed time, T1 and T2 groups showed less changes than that of control group. Lipid peroxidation appeared in a little bit changes regardless of the processing and storage days, but protein spoilages in T1 and T2 groups were found by lower changes when compared with the control group. As the results of sensory evaluation, T1 and T2 groups during storage had the better taste, flavor and acceptability than those of control and T3 groups. Therefore, we suggest that kimchi duruchigi supplemented with the RCM extract is a possible of improving the storage stability and product preference.

감마선 조사가 건조-발효소시지의 Trans 지방산, 유리아미노산 및 관능검사 특성에 미치는 영향

김일석,양미라,조철훈,안동욱,강석남,Kim, Il-Suk,Yang, Mi-Ra,Jo, Cheorun,Ahn, Dong-Uk,Kang, Suk-Nam 한국축산식품학회 2011 한국축산식품학회지 Vol.31 No.4

본 연구는 감마선 조사가 건조-발효햄의 조직감, 지방산, 유리아미노산 및 관능적 특성에 미치는 영향을 조사하기 위해 실시하였다. 경도(hardness) 및 부착성(adhesiveness) 의 경우 조사 처리구가 유의적으로 낮게 나타났다(p<0.01). 검성(gumminess)의 경우에는 2 및 4 kGy처리구가 대조구 및 1 kGy처리구보다 유의적으로 높은 값을 나타내었다(p<0.01). 지방산의 경우 처리구의 포화지방산(SFA)(C14:0, C16:0, C18:0)은 유의적으로 높았고(p<0.05), 불포화지방산 (UFA)(C16:1, C18:1 및 C18:3), trans 지방산, n-3 및 n-6 지방산 의 함량은 4 kGy처리에서 감소하였다(p<0.05). 감마선 조사처리는 phosposerine, aspartic acid, glutamic acid를 증가 시켰으나, lysine은 감소시켰다(p<0.05). 관능검사의 경우, 황취(sulfur odor) 및 지방산화 맛(fat pungent flavor)은 4 kGy에서 가장 높게 나타났으며(p<0.05), 곰팡이 냄새(moldy odor) 및 곰팡이 맛(moldy flavor)은 낮게 나타났다(p<0.05). 이상의 결과 감마선 조사가 조직감, 지방산조성 및 관능적 특성에 영향을 미쳤다. In this study, the effects of gamma-irradiation (1, 2 and 4 kGy) on texture profiles, fatty acid composition, free amino acids and sensory evaluation of dry-fermented sausage were evaluated. The hardness and adhesiveness of irradiated samples were significantly lower (p<0.01) than that of the control, while the gumminess of samples irradiated with 2 and 4 kGy was higher than the other tested samples (p<0.01). The sample irradiated at 4 kGy had a higher saturated fatty acid (SFA) content (C14:0, C16:0, C18:0) and significantly lower (p<0.05) unsaturated fatty acid content (UFA) (C16:1, C18:1, C18:3), trans, n-3 and n-6 fatty acid than the non-irradiated sample. Gamma-irradiation resulted in an increase (p<0.05) in phosposerine, aspartic acid and glutamic acid and a decrease (p<0.05) in glutamic acid in free amino acids. For the samples irradiated at 4 kGy, the sulfur odor and fat pungent flavor were significantly higher (p<0.05) and the moldy odor and moldy flavor were significantly lower than the control sample. In conclusion, gamma-irradiation had a significant effect on the texture profiles, fatty acid composition and sensory evaluation of dry-fermented sausage.

크론씨병 치험 1례

나원경,양미라,이해자,박은정,Na, Won-Gyung,Yang, Mi-Ra,Lee, Hae-Ja,Park, Eun-Jung 대한한방소아과학회 2002 대한한방소아과학회지 Vol.16 No.2

Crohn's disease is an indolent, chronic inflammatory bowel disease capable of involving the entire alimentary tract. The exact etiology and pathogenesis remain unknown despite a long and intensive research, but the finding of various abnormalities of the immune response in patients with Crohn's disease has led to the concepts that immune mechanism is involved in the pathogenesis of this disease. Recently, we have experienced a case of Crohn's disease. So the purpose of this study is to examine the efficacy of Oriental medicine for Crohn's disease.

소아 만성 부비동염(副鼻洞炎)(축농증)의 한방치료효과 후 재발율에 대한 임상적 연구

이해자,박은정,양미라,Lee Hai-Ja,Park Eun-Jung,Yang Mi-Ra 대한한방소아과학회 2000 대한한방소아과학회지 Vol.14 No.1

Background: In recent years, pediatric chronic sinusitis patients who didn't respond with antibiotics were increasing, but there were a few reports on recurrence rate of the herbal medicine therapy treating pediatric chronic sinusitis, so this report was studied. Objective: To know the recurrence rate of herbal medicine therapy in the chronic sinusitis using follow-up investigation. Materials and methods: Thirty four patients( 16 male and 18 female) treated in our hospital between December 1998 and August 1999 were studied. Ages ranged from 4 to 13 years (mean age :7.7 years). Twenty five patients(66%) had a underlying family history (allergy or sinusitis of family). In the past history, 32 patients (86%) had asthma, allergy of milk, atopic dermatitis, bronchiolitis and irritable bowel syndrome. Duration of treatment were from eleven to eighteen month (mean:14.3 month). Results: Of the 34 patients, 31 patients were improvement, 3 patients not. Of the 31 patients, thirty patients showed not recurrent (91%). Two patients showed no significant interval change(6%) and one patient was aggrevated (3%). The degree of the Health , thinking of protector for the herb medicine therapy and improvement of sinusitis were significant statistically. (significant <0.005) Conclusion: We know that herbal medicine therapy is the effective treatment of pediatric chronic sinusitis.