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안종모,Ahn, Jong-Mo 대한안면통증구강내과학회 2012 Journal of Oral Medicine and Pain Vol.37 No.2
위염 및 위암 등의 발생과 관련되어 있는 Helicobacter pylori(H. pylori)는 구강의 치태와 타액에서 주로 발견이 된다. 유년시절 동안 주로 감염되는 것으로 알려져 있지만 감염경로는 불분명하다. 구강이 H. pylori의 두 번째 서식지로서 전염경로 및 위장내 H. pylori의 제균 후 재감염에 중요한 영향을 끼칠 수 있는지는 논쟁이 되고 있다. 따라서 본 저자는 문헌고찰을 통하여 구강 내에 존재하는 H. pylori에 관하여 알아보고자 하였다. 위장에 존재하는 H. pylori는 위인두반사나 구토에 의해 구강 내 발현될 수도 있으나, 구강과 위의 감염은 서로 관련성이 없는 것으로 보고되고 있다. 진단방법으로는 혈청학적검사, 요소호기검사, 중합효소연쇄반응(polymerase chain reaction: PCR)방법, Urease검사, 조직검사 등이 있으나, 타액과 치태에서는 nested PCR 방법이 주로 추천되어 진다. 구강 내 감염율은 다양하게 나타나며, 치과질환과의 연관성은 없는 것으로 사료된다. 그러나 치주질환 환자의 구강 내에서 발현율은 높게 나타나므로, 주의가 요구되며 향균 구강세척제의 사용이 권유된다. 결과적으로 구강 내 H. pylori는 정상세균총으로 사료되며, 향후 구강내 H. pylori에 관한 추가적인 많은 연구가 필요하리라 사료된다. Helicobacter pylori(H. pylori) associated with gastritis and gastric cancer is mainly detected dental plaque and saliva in the oral cavity. Most infection is probably acquired in childhood, but the route of transmission is not clear. The oral cavity has been indicated as secondary reservoir of H. pylori, and may therefore be argued in the route of transmission and reinfection of the stomach which follows treatment of H. pylori infection. So this review aimed to discuss about H. pylori in the oral cavity. H. pylori in stomach can appear in the oral cavity by gastroesophageal reflex or vomiting, but infection of stomach and oral cavity is different. Diagnostic methods are serological method, urea breath test, PCR method, urease test, histologic method and so on. Nested PCR recommend for detection of H. pylori in saliva and dental plaque. H. pylori infection in the oral cavity appear variously and is no relation with dental diseases. The antimicrobial mouthrinse recommend in patients with periodontal diseases because of high detection rate fo H. pylori. Thus H. pylori may be considered as the normal oral microflora.
안종모(Jong-Mo Ahn) 대한치과의사협회 2011 대한치과의사협회지 Vol.49 No.6
Neuropathic orofacial pain(Nop) is initiated or caused by a priomary lesion or dysfunction in the peripheral nervonus system or the central nervous system. NOP is divided into paroxysmal and continuous by duration of pain. NOP is important for dentists, because they can occur after dental procedures, such as extractions, endodontic treatment, and dental implant insertion. Dentists should have concern about NOP, because it is difficult to diagnose and treat.
안종모 ( Jong Mo Ahn ),김준호 ( Jun Ho Kim ),홍성주 ( Seong Ju Hong ) 조선대학교 치의학연구원 2011 Oral Biology Research (Oral Biol Res) Vol.35 No.2
Trigeminal neuralgia (TN) is a severe unilateral paroxysmal, lacinating facial pain. The diagnosis of TN is based on several characteristic clinical features. The purpose of this study was to evaluate the clinical manifestations of TN patients treated at the Department of Oral Medicine, Chosun University Dental Hospital. Materials and Methods: A total of 56 patients with TN from January 2008 to December 2009 was included for this study. We investigated the gender, age and systemic diseases of patients, the sites of pain, the methods and duration of treatment and the course that comes to department of oral medicine. 89.3% of the patients were over 40 years of age and 64.3% were women. Results: Patients with TN had mainly diseases of the circulatory system and endocrine diseases. The two most frequently involved trigeminal nerve brandches were mandibular (53.6%) and maxillary (32.1%) branches. 94.6% of the patients were treated by medication and 92.8% of the patients controlled the pain within 6 months. And we could know that 32.1% of the patients were comes to the Department of Oral Medicine within 2 months after occurrence of the symptom and 89.3% of the patients were comes to the Department of Oral Medicine via other clinics or hospitals and other Department of Chosun Univerisity Dental Hospital.