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박재한,도영록,김지수 대한의사협회 2018 대한의사협회지 Vol.61 No.1
Although dizziness is common, it is one of the most challenging symptoms in clinical medicine. Defining the type of dizziness has been considered the first step when approaching patients with dizziness. This approach was based on the belief that each type of dizziness reflects a specific underlying mechanism. A more recent approach involves grouping patients into 4 major categories: 1) acute prolonged spontaneous dizziness, 2) recurrent spontaneous dizziness, 3) recurrent positional dizziness, and 4) chronic persistent dizziness and imbalance. Vestibular neuritis and strokes are the most common causes of acute prolonged spontaneous dizziness, and neuro-otologic examination findings play a key role in the differential diagnosis. Careful history-taking is extremely important in diagnosing the disorders that cause recurrent spontaneous dizziness since the findings of the clinical examination and laboratory evaluations are often negative without a confirmatory diagnostic tool. Benign paroxysmal positional vertigo is a predominant cause of recurrent positional vertigo and can easily be treated with canalith-repositioning maneuvers. Chronic persistent dizziness and imbalance occur in various degenerative or psychiatric disorders that frequently require a referral to a specialist. This new approach may be more practical for managing patients with dizziness.
치주낭 탐침깊이와 치은연하치태내 Trypsin-like activity와의 관계
박재한,한경윤,Park, Jea-Han,Han, Kyung-Yoon 대한치주과학회 1993 Journal of Periodontal & Implant Science Vol.23 No.3
In order to determine the relationship between probing pocket depth and trypsin-like activity in subgingival plaque, probing pocket depth and loss of attachment were measured by Michigan-O probe on mandibular incisors of 30 patients with adult periodontitis. And the trypsin-like activity of Treponema denticola, Porphyromonas gingivalis, and Bacteroides forsythus was evaluated by the hydrolysis of N-Benzoyl-DL-Arginine-2-Naphthyla-mide (BANA) using PerioScan reagent cards(Oral-B Laboratories, Redwood City, CA). The obtained data were statistically analyzed by Microstat program. The results were as follows. 1. The number of teeth showing negative trypsin-like activity was more in shallow periodontal pocket groups, but the number of teeth showing positive trypsin-like activity was more in deep periodontal pocket groups. 2. There was a significant positive correlation between probing pocket depth and trypsin-like activity in subgingival plaque(y=0.413X - 0.955, r = 0.7024, p<0.001). 3. There was no consistent relationship between loss of attachment and trypsin-like activity in subgingival plaque(p>0.01).
박재한,석정임,이동국 대한임상신경생리학회 2006 Annals of Clinical Neurophysiology Vol.8 No.2
There have been several reports about coexistence of myasthenia and other autoimmune disease. Psoriasis is a papulosquamous disease defined by erythematous plaques with a silvery scale and a T-cell-mediated autoimmune disease. We report a case of a 49-year-old an with generalized myasthenia gravis (MG) superimposed by psoriasis. MG was diagnosed by clinical symptoms, increased acetylcholine receptor antibody titer and repetitive nerve stimulation test. Psoriasis was diagnosed by clinical manifestations and specific skin biopsy findings. MG and psoriasis are both autoimmune diseases. The coexistence of MG and psoriasis suggest a close connection of pathogenesis.
Thermal Cycling 이 광중합형 글래스아이 오노머 수복재의 압축강도에 미치는 영향
박재한 朝鮮大學校 口腔生物學硏究所 1999 Oral Biology Research (Oral Biol Res) Vol.23 No.2
This study was performed to evaluate the effect of thermal cycling on the compressive set glass ionomer material(Fuji Ⅱ), two resin-modified glass-ionomer materials(Fuji Ⅱ LC, Vitremer), and two polyacid-modified composite resins(Compoglass, Dyract). The compressive test specimens were fabricated in a teflon mold giving 3 ㎜ in diameter and 6 ㎜ in length. All samples were divided into two groups. Group 1 was immersed in a 37℃ distilled water for 10 dsys. Group 2 was subjected to 10,000 thermal cycles between 5℃ and 55℃, and the immersion time in each bath was 15 seconds per cycle. Compressive test was subjected to a crosshead speed of 0.5㎜/min. The results obtained were summarized as follows; 1. The compressive strength values of the tested resin-modified glass ionomer materials and polyacid-modified resin composites were inferior to that of hybrid resin composite. 2. The compressive strength values of polyacid-modified resin composites were higher than those of resin-modified glass-ionomer materials, which were much higher than that of conventional glass-ionomer materials. 3. The highest compressive strength value of 45.4 MPa was observed in the DR group and the lowest value of 13.3 MPa was observed in the FL group after the thermal cyling test, and the strength of polyacid-modified composite groups were significantly higher than those of other groups(p<0.05). 4. The compressive strength of polyacid-modified resin composites showed that the DR group containing the crushed fillers was higher than that of the CG group containing the spherical fillers.