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Paragonimus Westermani의 이소기생의 1례
박경희(KH Park),이정기(JG Rhee),최응환(EW Choe),문영회(YH Moon) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.1
We are going to report a rare case that Paragonimus Westermani involved the female internal genital orgens, such as bilateral adnexae and overiea. At first, We were impressed it as the pelvic tuberculosis at laparotomy showing marked adhesion to greater omentum and small sized multiple nodular appearance. Therefore its defenition, frequency, clinical findings, symptoms and treatments were briefly discussed.
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인간 융모 성선자극홀몬 (hCG) 에 의한 생쥐의 뇌 소교세포에서 산화질소 (NO) 의 생성
문영회,민부기,김형민 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.8
Nitric oxide ( NO ) is now recognized as a mediator of several biological and immunological functions , but unlike classical neurotransmitters , NO simply diffuse of the postsynaptic cell and around affecting cells. Human chorionic gonadotropin ( hCG ) , produced by placental trophoblasts may act as stimulator on NO synthesis in oocytes of mouse`s ovary. How-ever, in the various organs or cells , the action of hCG on NO synthesis is unknown. We have examined that the effect of hCG on NO synthesis in microglial cells of murine`s brain , using the Griess method. And this study was evident that hCG did not induce NO produc-tion without recombinant interferon gamma ( rIFN-γ) , whereas hCG ( 10∼500 IU/ml ) with rIFN-γ effectively produced NO in microglial cells of brain. As result , NO production in microglial cells increased most significantly in dose of 100 IU/ml of the hCG and the pro-duction of NO was dependent on the dose of hCG ( Table 1 and Fig. 1 ). And NG-monomethyl-L-arginine ( NGMMA ) , competitive inhibitor of NO synthase , reduced the NO production by hCG stimulation with rIFN-γ in microglial cells of murine. Conclusively , this study sugge-sted that hCG stimulate NO production at microglial cells in brain , which may be an important factor for mediating immune and neuroendocrinologic regulation in nervous system.
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