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Trichloroethylene , Tetrachloroethylene 및 1,1,1-Trichloroethane 이 흰쥐에 미치는 영향에 관한 조직학적 관찰
노명희,김옥용 ( Myung Hee Rho,Ok Yong Kim ) 한국환경생물학회 1990 환경생물 : 환경생물학회지 Vol.8 No.1
Effects of trichloroethylene (TrCE), tetrachloroethylene (TtCE) and 1, 1, 1-trichloroethane (1-TrCE) on the ultrastructural changes occuring in the liver, lung and spleen of rats were observed. Mitochondria were swollen and had dense aggregated matrix. Rough endoplasmic reticulums were vesiculated and free ribosomes were increased in cytoplasms of hepatocyte and splenic reticulocyte after treatment of these chemicals. These ultrastructural changes in TrCE treated group were more severe than those of TtCE or 1-TrCE treated group. When TtCE was treated, pathologic changes of lung cells were observed conspicuously comparing to the other cells, especially lysosomes were increased.
권영일 ( Young Il Kwon ),노명희 ( Myung Hee Rho ) 대한임상검사과학회 1999 대한임상검사과학회지(KJCLS) Vol.31 No.2
The purpose of this investigation was a market ana1ysis of import diagnostic reagents to Korea in 1998. The tota1 import money was $51 ,684,601 and major import countη was U .S.A., France, Japan, Swiss, Germany, U.K. and Ita1y by priority of money. About 79% of tota1 amount of money(52 mil1ion dollar) was imported from U.S.A., France and Japan. These countries was in possesion of 42.8%(22 million dollar), 22.8%(12 million dollar) and 13.4%(7 mil1ion dollar) respectively. The tota1 import quantiη(kits and packs) was 3,429,832 and then U.S.A., France and Japan was taken 53,6%, 19.6% and 7.9% respectively. In the itemized import ana1ysis, immunoserology and c1inica1 chemistη parts took 51.2% and 28.9% respectively. The remaining 20% formed urina1ysis(9.6%) , microbiology(4.0%) , diagnostic pathology(O.4%), therapeutic drug testing( 1.3%), hematology(2.9%), and etc( 1.8%).
Hitachi 736-40 과 7600-110 모델의 풀혈청을 이용한 정밀도 비교와 정상범위 데이터의 분산 비교
권영일 ( Young Il Kwon ),노명희 ( Myung Hee Rho ),박찬호 ( Chan Ho Park ) 대한임상검사과학회 1999 대한임상검사과학회지(KJCLS) Vol.31 No.2
The new Hitachi 7600-110 is clinical chemistIy ana1yzer of module combinated analyzer(D-moduel: mu1ti-sample analyses, P-module: multi-item ana1yses, Ion selective electrodes). In the present paper, we compared the precision of Hitachi 736-40 and 7600-110 with pooled serum and the dispersion of data in normal ranges. The coefficients of variation(CVs) for pooled serum of Hitachi 736-40 and 7600-110 were : for AST , 4.28 and 3.87%; for ALT , 10.71 and 7.33%; for A1k. phosphatase, 2.73 and 3.23%; for T. protein, 1. 94 and 2.74%; for r -GT, 13.40 and 3.87%; for T. bilirubin, 6.94 and 7.76%; for glucose, 1. 76 and 2.4 1%; for BUN , 3.15 and 2.50%; for creatinine, 2.64 and 2.94%; for triglyceride, 3.36 and 2.72%; for tota1 cholesterol, 1.85; and 2.56% and for T. ca1 cium 1. 70 and 2.77, respectively. The determined data between the Hitachi 736-40 and 7600-110 were significantly defferent at P ≤0.05 except for triglyceride and T. cholesterol.The dispersion of norma1 groups for monthly average were 4.02 -4 7.4 4%(CVs) with Hitachi 736-40 and 4.17-49.38%(CVs) with Hitachi 7600-110.
Total antioxidant status (TAS) 참고치 및 고콜레스테롤혈증, 당뇨병과의 관련성에 관한 연구
권영일 ( Young Il Kwon ),서은주 ( Eun Ju Seo ),홍효선 ( Hyo Sun Hong ),안희은 ( Hee Eun Ahn ),박찬호 ( Chan Ho Park ),노명희 ( Myung Hee Rho ) 대한임상검사과학회 1999 대한임상검사과학회지(KJCLS) Vol.31 No.2
Introduction : The Object of this study is to investigate the reference ranges of total antioxidant status(TAS) according to age and sex in korea. The human body is constantly under attack from free radicals. Free radica1s are highly reactive molecules and once formed, attack cell structures with the body. As a resu1t, free radicals have been implicated in numerous disease. In hea1thy individua1s, the antioxidant system defends tissues against free radica1 attack. Methods and materials : We measured the tota1 antioxidant status of 90 norma1 group, 30 diabetes group and 30 hypercholesterolemia group. (The each group sex ratio : ha1f to ha1ij For each test, age and sex related variations were assessed and reference values were estimated for three different age groups.(below 20, 21-40, above 41) TAS measured by Randox Tota1 Antioxidant reagent and Hitachi 7150. Results : ’fhe reference va1ues according to age were 0.930- 1.332mmolfL in below 20 years of age, 1.007 -1.391mmolfL in 21-40 years of age and 0.995- 1.295mmolfL inabove 41 year of age and showed statistica11y significant difference.(P<0.05) The Reference ranges of tota1 age group, ma1e and fema1e group were 0.991- 1.343mmolfL, 1.038- 1.370mmolfL, and 0.977 -1.285mmolfL respectively. Between the ma1e and fema1e group were statistically signficant difference.(P<0.05) The TAS means of diabetes and hypercholesterolemia were 1.26mmoljL and 1.23mmoljL respectively. TAS values of hypercholerterolemia an normal group were no significant difference whereas diabetes and normal group were significant difference.(P<O.OOl) Conclusions : We established that reference ranges were analyzed age and sex related variations for total antioxidant status. Between experimental groups showed generally significant differences. In the future, correct diagnosis of disease induced free radicals need to measure total antioxidant level and each antioxidants.
노명희,정경순,강지연 김천과학대학 2001 김천과학대학 논문집 Vol.27 No.-
The purpose of current study was to explore the cost - effcctiveness, health outcomes and family caregiver burdens of home care nursiny for stroke patients. Consideriny cost-effectiveness only home care is much better than institutional care for patients with chronic illness like strokes. But it remains controversal when the cost of family labour is considered. Also considering of care for patients with severe physical disabilities, institutional care is more appropriate than home care. Then decisions concerning the appropriate type of care setting for patients with severe chronic illness remain difficult In the view of health outcomes, home care based on appropriate service promotes activities of daily living (ADL), quality of life related to health and returning to daily life. However, family caregivers may have labour consume of physical, psychological, social and economical aspects and reach severe imbalance of life. Therefore, the authors suggest that it's necessary to develop effctive and economic home rehabilitation care programs supporting not only patients but also family caregivers
Powerlessness, Helplessness, Hopelessness의 개념적 특성 및 유사점과 차이점
노명희,정경순,강지연 김천과학대학 2001 김천과학대학 논문집 Vol.27 No.-
The purpose of this study was to detect each concept's characteristics resemblances, differences by finding out definition, contributions, antecedents, instrumentations, consequences of powerlessness, helplessness and hopelessness through reviewing literature. The concept of powerlessness, helplessness or hopelessness has been important elements of the lives of persons with chronic diseases. Their resemblances are negative emotion coming from loss of control and have effect on physical, psychological, sociological aspects of hearth A continued powerlessness leads to helplessness and hopelessness. If it is not controlled and even persisted in chronically, a person will learn helplessness and get into helplessness - hopelessness cycle. Their differences are as follows: Powerlessness is recognition that self-behavior will significantly have no influence on result. Attributions of feelings are lack of control, disorder of physical functions, disorder of role management, lack of knowledge or motivation. Antecedents are lack of physical, psychological and social power. It results in behavior and psychologic response and helplessness, despair, death. Helplessness is extinction of response that an organ can't control or avoid results. Attributions of feelings are lack of confidence, persistance, display and responsibility and negative recognition like depression and passive. Antecedents are recognition that some results are independent on self-response and lack of motivation to control results and lack of confidence on control and restrained learn response. It results in reduced motivation and life, disorder of recognizing fuction and emotion. Hopelessness is negative hoping systems on life of self and self-future. Attributions of feelings are disability, powerlessness, continuing disappointment-abandon cycling. Antecedents are lack of physical well-being, humanistic life, functional ability, role management ability, economics. It results in social isolation, physical symptoms, suicide, shortened life.