충청남도 산업간호사의 활동현황에 관한 조사연구

김순임,Kim, Sun-Im 한국지역사회간호학회 1990 지역사회간호학회지 Vol.2 No.1

학동들의 유행성이하선염 발생양상

김순임,Kim, Sun-Im 한국지역사회간호학회 1990 지역사회간호학회지 Vol.2 No.1

학동들의 유행성이하선염 발생양상을 파악하기 위하여 1978년 3월부터 8월까지 경북 안동시 안동초등학교 학생 2,754명 (남: 1,447, 여: 1,307)을 대상으로 연령별 예방접종상태와 발생율 및 발병율을 조사하고 월별 발생율, 예방접종 효과를 관찰하였다. 예방접종 실시율이 7세에서는 8.4%, 8세에서는 6.2%, 9세에서는 4.8%로 나타났으나 10세 이상에서는 전혀 예방접종을 받지 않았다.

추출 조건에 따른 오미자 추출물의 항산화 및 혈당 강하에 관한 연구

김순임 ( Sun Im Kim ),심기현 ( Ki Hyeun Sim ),주신윤 ( Shin Yoon Ju ),한영실 ( Young Sil Han ) 한국식품영양학회 2009 韓國食品營養學會誌 Vol.22 No.1

오미자의 전통식품소재로의 활용성을 높이기 위해 물과 에탄올, 그리고 추출온도와 시간을 달리하여 추출하여 얻은 추출물로부터 항산화능과 혈당 강하능을 살펴보았다. 총 페놀함량은 추출온도에 따른 차이를 크게 나타내었다. 60℃에서 추출하였을 때 실온에서 추출한 것보다 51~68% 더 높은 함량을 나타내었고, 또한 물 추출보다는 60% 에탄올로 추출하였을 때 더 높은 페놀을 함유한 것으로 나타났다. DPPH 유리 라디칼 소거능을 비롯한 ABTS+ 라디칼, Nitrite 소거능 또한 60℃에서 60% 에탄올로 추출하였을 때 유의적으로 가장 높았으며, 환원력도 60% 에탄올 추출물이 가장 높은 환원력을 나타내었다. 오미자 추출물의 인슐린 비의존형인 제2형 당뇨환자들의 식후 혈당을 저하시키는 효능을 검토하기 위해 α-glucosidase의 활성 저해력을 살펴본 결과, 5가지 추출 조건 중 60℃에서 60% 에탄올로 추출한 추출물이 유의적으로 가장 높은 저해력을 보이는 것으로 나타났다. 이상의 결과로 볼 때 오미자로부터 유용성분 용출 및 기능성 증대를 위해 60℃에서 60% 에탄올로 추출하는 것이 바람직하다고 생각된다. This study investigated anti oxidative and hypoglycemic activities of Omija for evaluation of usefulness as a functional food resource. Omija water extracts were extracted with water for 24 hr, 6 hr and 3 hr at room temperature, 60℃ and 100℃, respectively. Omija ethanol extracts were extracted with 60% ethanol for 24 hr and 3 hr at room temp temperature and 60℃, respectively. The antioxidant properties of Omija(Schizandra chinensis Baillon) extracts prepared under different extraction conditions were evaluated by a variety of radical scavenging assays including DPPH, ABTS+, and nitrite and reducing power. Hypoglycemic activity was examined for α-glucosidase inhibition using an in vitro model. The total phenolic content was also determined. Antioxidant activities of Omija were the highest in the group extracted with 60% ethanol for 3 hr. The ethanol extracts showed higher activity than water extracts. An extraction temperature was the highest in 60℃. The total phenolic content extracted with 60% ethanol for 3 hr at 60℃ was 530 mg GAE/100 g. The water extract extracted with water for 24 hr at room temperature showed the lowest antioxidant activity and phenolic content. α-glucosidase inhibitory activity was the highest in the group extracted with 60% ethanol for 3 hr at 60℃, followed by the group extracted with 60% ethanol for 24 hr. The results suggest that extraction of Omija by 60% ethanol for 3 hr at 60℃ will be useful as a functional food resource with natural antioxidants and hypoglycemic activities.

임상연구 : 두부 외회전이 우측 내경정맥과 경동맥의 해부학적 위치관계에 미치는 영향

김순임 ( Soon Im Kim ),강제현 ( Je Hyun Kang ),백영희 ( Young Hee Baek ),김상호 ( Sang Ho Kim ),옥시영 ( Si Young Ok ),김선종 ( Sun Chong Kim ) 대한마취과학회 2008 Korean Journal of Anesthesiology Vol.55 No.5

Background: The purpose of this study was to evaluate the effect of head rotation on the anatomical relationship of the right internal jugular vein (RIJV) and the carotid artery (CA) with using ultrasound images in Korean patients. Methods: We investigated 117 patients (age range: 16-87 years old) who were placed in the supine position, but not in the Trendelenburg position. An ultrasound probe was placed on the right neck at the apex of the triangle formed by the head of the sternocleidomastoid muscle and the clavicle, and it was directed toward the ipsilateral nipple at a 30 degree angle to the coronal plane. For each head rotation (0, 30, 60 degrees), we measured the horizontal diameter of the RIJV and CA, and the percentage of overlap of the CA and the RIJV with using an ultrasound system. Results: The mean RIJV diameter was 18.4±4.3 mm and the mean CA diameter was 7.5±1.2 mm at the neutral head position. Following head rotation, the percentage overlap of the CA and RIJV increased significantly (0°: 32.7%, 30°: 45.4%, 60°: 57.0%) (P<0.05). The percentage overlap of the CA and RIJV in the neutral head position increased more in the patients with a BMI over 25. However, age did not have any effect on the percentage of overlap. Conclusions: Head rotation toward the contralateral side increases the percentage of overlap of the CA and RIJV. To decrease the risk of CA puncture, rotate the head from the neutral position as little as possible when performing RIJV catheterization. (Korean J Anesthesiol 2008;55:538~42)

실험연구 : 흰쥐 횡격막 신경근 표본에서 Vancomycin이 비탈분극성 근이완제의 신경근 차단에 미치는 영향

김순임 ( Soon Im Kim ),한창윤 ( Chang Yoon Han ),정호순 ( Ho Soon Jung ),이정석 ( Jeong Seok Lee ),옥시영 ( Si Young Ok ),김선종 ( Sun Chong Kim ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.6

Background: Vancomycin is frequently used as a prophylactic antibiotic in patients undergoing cardiac and orthopedic surgical procedures. However, the interactions of vancomycin with non-depolarizing muscle relaxant have not yet been reported on. Therefore, we studied the effects of vancomycin on the neuromuscular block of vecuronium, rocuronium and atracurium in vitro. Methods: Square wave, 0.1 Hz supramaximal stimuli were applied to the phrenic nerve-hemidiaphragm preparation of the rat and the twitch height response was recorded. We measured cumulative concentration response curves of vecuronium, rocuronium or atracurium, respectively, and also those of the rats that were pretreated with vancomycin (20μg/ml). The EC50 and EC95 of these muscle relaxants alone and those of the rats pretreated with vancomycin were calculated with using an inhibitory sigmoid Emax model. Results: Vancomycin alone did not depress the twitch height. The pretreated vancomycin (20μg/ml) did not affect the EC50 and EC95 of vecuronium or rocuronium, but it significantly reduced the EC50 and EC95 of atracurium (P < 0.05). Conclusions: Vancomycin itself does not have neuromuscular blocking properties. Vancomycin does not affect the neuromuscular blockade induced by vecuronium or rocuronium, but it significantly enhances the neuromuscular blockade induced by atracurium. (Korean J Anesthesiol 2006; 51: 727~32)

임상연구 : 소아에서 사시 교정 수술 후 Ondansetron과 Dexamethasone의 병용투여가 구토 예방에 미치는 효과

김순임 ( Soon Im Kim ),이정석 ( Jeong Seok Lee ),김수현 ( Soo Hyun Kim ),옥시영 ( Si Young Ok ),김선종 ( Sun Chong Kim ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.3

Background: Postoperative vomiting (POV) is a common complication after pediatric strabismus surgery. The aim of this study was to evaluate the prophylactic antiemetic effects of a combination of ondansetron with dexamethasone after strabismus surgery in children. Methods: In this prospective, randomized, double-blind, placebo-controlled study, 126 healthy children, aged 3-10 years, who underwent strabismus surgery under general anesthesia using sevoflurane were examined. The patients were divided randomly into three groups: Patients who received 100μg/kg ondansetron with 100 μg/kg dexamethasone (OD group, n = 42); 100μg/kg ondansetron (O group, n = 42); and saline as placebo (P group, n = 42) after the induction of anesthesia. The incidence of vomiting, the patient`s distress due to vomiting, the need for rescue antiemetics and parental satisfaction during the first 24 h after surgery were evaluated. Results: The incidence of vomiting in group OD (5%) and group O (17%) during the first 24 h after surgery were significantly lower than in group P (40%) (P < 0.001, P < 0.05, respectively). The level of distress of the patients in group OD during the first 6 h after surgery was significantly lower than in group P (P < 0.05). The parents in group OD were more satisfied than those in group P (P < 0.05). However, the incidence of vomiting, patient`s distress, need for rescue antiemetics, and parental satisfaction were comparable between groups OD and group D. Conclusions: A combination of ondansetron with dexamethasone and ondansetron alone were equally effective in preventing vomiting after strabismus surgery in children. However the combination of ondansetron with dexamerhasone, but not ondamsetrone alone, is more effective in reducing the level of patient`s distress and incresing the level of parental satisfaction than the placebo. (Korean J Anesthesiol 2006; 51: 324~9)

초고압 기술이 자작나무 수액의 저장성 향상에 미치는 영향

최경화,김순임,이동욱,전정태,Choi, Kyung Hwa,Kim, Sun Im,lee, Dong Uk,Jeon, Jung Tae 한국식품저장유통학회 2017 한국식품저장유통학회지 Vol.24 No.3

초고압 공정(HPP)은 비가열 공정 중 하나로 식품 중의 세균 증식을 억제하는 방법으로 근래 들어 상업적으로 각광 받고 있다. 자작나무 수액은 여과 및 UV 살균과정을 거쳐 유통되지만 상업적으로 사용하기에는 식품공전 미생물 규격에 적합하지 않아 추가 살균처리 없이 유통을 하기에는 적합하지 않은 단점이 있었다. 본 연구에서는 그 단점을 보완하고 저장유통기한을 연장하기 위해 비가열가공 살균법으로 최근 주목받고 있는 HPP를 적용하고자 하였다. 최적 조건을 설정하기 위해 HPP 조건을 달리 하여 63일 동안 저장하여 변화를 관찰하였고, 그 결과 압력이 높고 처리시간이 길어질수록 미생물제어에 효과적이였다. 설정된 550 MPa, 120 sec의 조건으로 HPP 처리한 후 $5^{\circ}C$와 $10^{\circ}C$에 저장하며 미생물 및 품질변화를 관찰하였다. HPP 미처리군의 경우에는 4-7일차에 급격한 미생물 증식 및 이화학 변화가 일어났지만 HPP 처리군의 경우 $5^{\circ}C$에서 45일, $10^{\circ}C$에서 28일간 저장하는 동안 일반세균, 대장균, 대장균군, 진균 모두 증식이 없어 미생물학적으로 안전한 것으로 나타났다. 또한, pH, 산도, 당도, 탁도 및 갈변도의 변화를 살펴본 결과 $5^{\circ}C$에서는 45일까지 변화가 없었고, $10^{\circ}C$에서는 28일 차에서 pH 감소, 산도, 갈변도, 탁도의 증가로 급격한 변화로 24일 저장하는 것이 이화학적으로도 안정하다고 평가하였다. 이상의 결과로 볼 때 자작나무 수액은 효과적인 살균처리를 하지 않으면 미생물증식, 탁도 및 갈변도 변화, 산도증가로 유통기한이 4일 이하로 저장성이 많이 낮지만, HPP 처리함으로 인해 미생물 증식을 막고 그에 따른 수액의 이화학적 안정성을 확보하여 수액의 품질수명을 기존 미처리군에 비해 6배 연장시킬 수 있을 것으로 판단된다. Effects of high pressure processing on physicochemical and microorganisms properties in birch sap were investigated using variable high pressure processing conditions. The viable cell counts of untreated birch sap was 4.0 log CFU, whereas high pressure processed sap were not detected. In birch sap was treated with 450 to 550 MPa, microorganisms were not detected during storage period, and physicochemical properties as well as color were slightly changed. The more processing time and pressure, its quality variations were more stable and then its optimum processing condition was determined with 120 sec at 550 MPa. The microorganisms and physicochemical properties of treated birch sap were investigated during storage at $5^{\circ}C$ and $10^{\circ}C$ for 45 and 28 days. Changes of physicochemical properties of treated birch sap were smaller than those of the untreated, but viable cell count were not detected during storage period. As for pH, $^{\circ}Brix$, and turbidity result of birch sap, quality shelf life of control and treatment were 4 and 24 days, respectively. Especially, ${\Delta}E$ value of instrumental color was untreated birch sap 4 days similar with the high pressure processed it for 28 days. These results indicated that the high pressure processing can be used as an effective method to improve the shelf life of birch sap.

충청남북도 산업간호사의 업문 분석 및 이용실태에 관한 조사연구

왕명자,김순임,Wang, Myeong-Ja,Kim, Sun-Im 한국지역사회간호학회 1990 지역사회간호학회지 Vol.2 No.1

충청남북도 산업간호사의 업무 분석 및 이용실태에 관한 조사 연구

왕명자,김순임,Wang, Myeong-Ja,Kim, Sun-Im 한국지역사회간호학회 1989 지역사회간호학회지 Vol.1 No.1

수술 중 사용한 Remifentanil 지속 정주가 수술 후 요축적 발생에 미치는 영향

김문규 ( Mun Gyu Kim ),김순임 ( Soon Im Kim ),두승환 ( Seung Whan Doo ),옥시영 ( Si Young Ok ),김선종 ( Sun Chong Kim ),양원재 ( Won Jae Yang ) 대한마취과학회 2008 Korean Journal of Anesthesiology Vol.55 No.1