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      • KCI등재

        Relationship between anterior disc displacement with/without reduction and effusion in temporomandibular disorder patients using magnetic resonance imaging

        고광준,박하나,김경아 대한영상치의학회 2013 Imaging Science in Dentistry Vol.43 No.4

        Purpose: This study was performed to evaluate the relationship between anterior disc displacement and effusion in temporomandibular disorder (TMD) patients using magnetic resonance imaging (MRI). Materials and Methods: The study subjects included 253 TMD patients. MRI examinations were performed using a 1.5 T MRI scanner. T1- and T2-weighted images with para-sagittal and para-coronal images were obtained. According to the MRI findings, temporomandibular joint (TMJ) disc positions were divided into 3 subgroups: normal, anterior disc displacement with reduction (DWR), and anterior disc displacement without reduction (DWOR). The cases of effusion were divided into 4 groups: normal, mild (E1), moderate (E2), and marked effusion (E3). Statistical analysis was made by the Fisher’s exact test using SPSS (version 12.0, SPSS Inc., Chicago, IL, USA). Results: The subjects consisted of 62 males and 191 females with a mean age of 28.5 years. Of the 253 patients, T1- and T2-weighted images revealed 34 (13.4%) normal, DWR in 103 (40.7%), and DWOR in 116 (45.9%) on the right side and 37 (14.6%) normal, DWR in 94 (37.2%), and DWOR in 122 (48.2%) joints on the left side. Also, T2-images revealed 82 (32.4%) normal, 78 (30.8%) E1, 51 (20.2%) E2, and 42 (16.6%) E3 joints on the right side and 79 (31.2%) normal, 85 (33.6%) E1, 57 (22.5%) E2, and 32 (12.7%) E3 on the left side. There was no difference between the right and left side. Conclusion: Anterior disc displacement was not related to the MRI findings of effusion in TMD patients (P>0.05).

      • KCI등재

        50대 남성의 운동 유발성 고혈압 반응과 동맥경직도 간의 연관성

        고광준,하지철,강설중 대한운동학회 2016 아시아 운동학 학술지 Vol.18 No.2

        [PURPOSE] This study attempted to show the relationship between exercise-induced hypertension response and arterial stiffness in men aged 50 years. [METHODS] The subjects of the study were adults male with exercise induced hypertension group (n=45, age 56.22±2.60 years) and control group (n=61, age 56.01±1.57 years) who had undergone exercise test and arterial stiffness test. Exercise induces hypertension is defined as a peak systolic blood pressure ≥210mmHg during treadmill tests. Exercise stress test was conducted using modified Balke protocol. Arterial stiffness was assessed based on brachial-ankle pulse wave velocity (baPWV). [RESULTS] Exercise induced hypertension group showed significantly higher baPWV than that of control group (1416.5±154.09cm/sec vs. 1309.5±127.76cm/sec, p<.001). The peak systolic blood pressure was correlated with the resting heart rate (r=0.198, p<.05), resting systolic blood pressure (r=0.190, p<.05), and baPWV (r=0.461, p<.001). In multiple linear regression analysis, we found that the baPWV was a significant predictor of peak systolic blood pressure (β=0.429, p<.001). [CONCLUSIONS] Exaggerated blood pressure response to exercise was associated with arterial stiffness.

      • SCOPUSKCI등재

        워터스촬영법과 파노라마촬영법을 이용한 상악동염에 관한 방사선학적 연구

        고광준 大韓口腔顎顔面 放射線學會 1987 Imaging Science in Dentistry Vol.17 No.1

        The purpose of this study was to evaluate the specialized Orthopantomograms and standard films compared with Waters' views in the diagnosis of maxillary sinusitis. The author analysed the types of mucosal thickening, the types of bony wall change, the relation between the types of chief complaints and mucosal thickening on the Waters' views of 156 patients with 206 maxillary sinuses demonstrating radiographic changes. And the pathologic change of antral floor was observed on 187 standard films and total amount of agreement in the diagnosis of maxillary sinusitis was evaluated at 156 specialized Orthopantomograms and 187 standard films. The results were obtained as followings. 1. Among 206 mucosal thickenings classified by 6 types, generalized increased radiopacity was 69 cases (33.5%) and the entire thickening of mucosa except an ostium area was 66 cases(32.0%). 2. The bony wall change was seen in 128 cases (62.1%) and the incidence of indistinct antral wall was the highest as 55 cases (43.0%) among 5 types. 3. Among 148 chief complaints, pain was 71 cases (48.0%), swelling was 19 cases (12.8%) and discomfort was 18 cases (12.2%). 4. The most frequent change of antral floor was indistinct antral floor as 25 cases(13.4%) and elevation of antral floor was 23 cases(12.3%). And the first molar presented the most frequent involvement of antral floor as 47 cases(57.3%). 5. In 156 specialized Orthopantomograms, 101 cases(49.0%) presented apparent increased radiopacity and 72 cases (35.0%) showed suspicious increased radiopacity in comparison with Waters' view. In 187 standard films, 47 cases (25.1%) presented apparent increased radiopacity and 53 cases(28.4%) showed suspicious increased radiopacity in comparison with Waters' views.

      • 정중 하악 낭종의 증례

        고광준 全北大學校 齒醫學硏究所 1987 전북치대논문집 Vol.5 No.1

        The median mandibular cyst is an extremely rare lesion of dispute origin that occurs in the midline of the mandible. While some authors believe that it results from proliferation of epithelial remnants entrapped during fusion of the mandibular arches, others suggest that it is a primordial odontogenic cyst that develops from a supernumerary enamel organs. This author experienced a case of median mandibular cyst in 40-year-old man with a complaint of swelling and pus discharge from anterior mandible. Panoramic view revealed well defined elliptical radiolucency extending from lower left 2nd premolar area to right lower 2nd premolar area. And periapical view showed scalloped appearance of superior margin of the lesion. This is a very interesting case that differential diagnosis has to consider traumatic bone cyst or radicular cyst radiographically.

      • SCOPUSKCI등재

        방사선조사가 백서 이하선의 선세포에 미치는 영향에 관한 전자현미경적 연구

        고광준,이상래,Ko Kwang Jun,Lee Sang Rae 대한영상치의학회 1988 Imaging Science in Dentistry Vol.18 No.1

        The author studied the histopathologic changes according to a single or a split dose and the time after irradiation on the acinar cells of rat parotid gland. 99 Sprague Dawley rats, weighing about l20gm, were divided into control and 3 experimental groups. In experimental groups, GroupⅠ and Ⅱ were delivered a single dose of l5Gy, 18Gy and Group Ⅲ and Ⅳ were delivered two equal split doses of 9Gy, 10.5Gy for a 4 hours interval, respectively. The experimental groups were delivered by a cobalt-60 teletherapy unit with a dose rate of 222cGy/min, source-skin distance of 50㎝, depth of l㎝ and a field size of l2×5㎝. The animals were sacrificed at 1, 2, 3, 6, 12 hours, 1, 3, 7 days after irradiation and examined by light and electron microscopy. The results were as follows: 1. As the radiation dose increased and the acinar cells delivered a single dose exposure were more damaged, and the change of acinar cells appeared faster than those of a split dose exposure. 2. The histopathologic change of acinar cells appeared at 1 hour after irradiation. The recovery from damaged acinar cells appeared at 1 day after irradiation and there was a tendency that the recovery from damage of a split dose exposure was somewhat later than that of a single dose exposure. 3. Light microscope showed atrophic change of acinar cells and nucleus, degeneration and vesicle formation of cytoplasm, widening of intercellular space and interlobular space. 4. Electron microscope showed loss of nuclear membrane, degeneration of nucleus and nucleoli, clumping of cytoplasm, widening and degeneration of rough endoplasmic reticulum, loss of cristae of mitochondria, lysosome, autophagosome and lipid droplet. 5. Electron microscopically, the change of rough endoplasmic reticulum was the most prominent and this appeared at 1 hour after irradiation as early changes of acinar cells. The nuclear change appeared at 2 hours after irradiation and the loss of cristae of mitochondria was observed at 2 hours after irradiation in all experimental groups.

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