문화대혁명(文化大革命) 시기 광서(廣西) 무선현(武宣縣)의 파벌투쟁과 식인(食人)

구소영 ( Ku¸ Soyoung ) 중국사학회 2021 中國史硏究 Vol.- No.134

In this article, I explored that the political causes of cannibalism in Wuxuan, Guangxi, China between spring and summer 1968. Wuxuan’s cannibalism was not just the result of the decisions of some leaders in the center of the Chinese Communist Party or intermediate leaders of the Guangxi Zhuang Autonomous Region. In addition, it cannot be seen only by the decision of the perpetrators, such as cadres of Wuxuan County and each district, and members of 'the Alliance Command'. It should be understood as a result of the interaction between the central and autonomous districts, prefectures, and districts on the literary situation of Guangxi Autonomous Region at the time. The center of China stimulated slaughter and cannibalism by defining the forces that denied the Revolutionary Committee as "enemies" of the counter-revolution and justifying attacks on them. In addition, the leaders of Preparation Group of the Guangxi Zhuang Autonomous Region Revolutionary Committee and Armed Forces Department attempted to achieve important ideological or political purposes by inducing many people to participate in attacks against those perceived as "class enemies" by stigmatizing political rivals by fabricating the "Anti-Communist National Salvation Army in Guangxi". In the meantime, the perpetrators of Wuxuan devised slaughter and cannibalism as the final solution that was very effective in preventive suppression of the current entire social group or members. Therefore, the strategic goals of the leaders of the central and Guangxi autonomous districts of China and the situational pressure of Wuxuan County interacted, acting as a strong motive for Wuxuan cannibalism in 1968.

The Study on the Semantic Function of Korean Distributive Plural Marker-tul

김소영 ( Kim¸ Soyoung ) 현대영미어문학회 2018 현대영미어문학회 추계학술대회 발표논문집 Vol.2018 No.-

캐나다의 임신중지 의료 지원 동향

이소영 ( Lee¸ Soyoung ) 한국보건사회연구원 2021 국제사회보장리뷰 Vol.18 No.-

캐나다에서 임신중지는 합법이다. 임신중지는 1988년 대법원이 형법에서 규정하는 낙태죄가 여성의 권리를 침해하기 때문에 위헌이라는 판결을 내림으로써 합법화가 되었다. 캐나다에서 임신중지가 합법화되는 이러한 과정은 우리나라에서 2019년 낙태죄를 규정하고 있는 형법 조항이 헌법불합치라는 판결을 내린 헌법재판소의 결정 과정과 유사한 점이 있다. 캐나다에서는 임신중지가 합법화된 이후 국가 의료보장 체계 내에서 임신중지 비용이 지원되고 상담 서비스가 활발히 이루어지고 있다. 그러나 접근성에서의 격차 문제와 임신중지를 제한하려는 지속적인 시도가 있다. 이러한 캐나다 사례는 입법 개정 과정에 있는 한국에 주는 시사점이 있다.

Determination of the optimal time for radioiodine therapy in anaplastic thyroid carcinoma using the adenovirus-mediated transfer of sodium iodide symporter gene

SO, YOUNG,LEE, YONG JIN,LEE, WON WOO,CHUNG, JUNE-KEY Spandidos Publications 2013 ONCOLOGY REPORTS Vol.29 No.4

Induction of autophagy by oleifolioside A in HCT-116 human colorectal cancer cells

An So-Young,An Hyun-Kyu,Kim Kyoung-Sook,Lee Young-Choon,Kim Seok-Ho 한국응용생명화학회 2023 Applied Biological Chemistry (Appl Biol Chem) Vol.66 No.-

In current study, we addressed the anti-cancer effect of oleifolioside A and its mechanism on the regulation of cell death in HCT-116 human colorectal cancer cells. Oleifolioside A inhibited HCT-116 cell proliferation and caused apoptosis associated with sequential activation of caspases 8 and 3, followed by PARP cleavage. Moreover, anti-LC3-positive granules and the increased LC3-II level were observed in HCT-116 cells treated with oleifolioside A, which is the specific characteristics of autophagy. Treatment of autophagy inhibiors, 3-MA and Wort, markedly accelerated the cell death by oleifolioside A and, furthermore, knockdown of Beclin-1 and Atg7 using shRNA increased oleifolioside A-induced apoptosis, suggesting a cytoprotective function of autophagy against oleifolioside A-triggered apoptosis. Treatment of HCT-116 cells with oleifolioside A time-dependently activated extracellular signal-regulated kinase (ERK). Oleifolioside A-induced autophagy was dramatically inhibited by pretreatment with an ERK inhibitor, U0126, which resulted in a marked reduction in cell viability. These findings indicate that oleifolioside A induce autophagy through ERK activation in HCT-116 cells and that autophagy suppression enhances apoptosis induced by oleifolioside A.

Transcription of human β-galactoside α2,6-sialyltransferase (hST6Gal I) is downregulated by curcumin through AMPK signaling in human colon carcinoma HCT116 cells

An So-Young,Kim Kyoung-Sook,Lee Young-Choon,Kim Seok-Ho 한국유전학회 2023 Genes & Genomics Vol.45 No.7

Background In this study, we observed that in human colon carcinoma HCT116 cells mRNA level of the human β-galactoside α2,6-sialyltransferase (hST6Gal I) was decreased by curcumin. FACS analysis using the α2,6-sialyl-specific lectin (SNA) also showed a noticeable decrease in binding to SNA by curcumin. Objective To investigate the mechanism for curcumin-triggered downregulation of hST6Gal I transcription. Methods The mRNA levels of nine kinds of hST genes were assessed by RT-PCR after curcumin was treated in HCT116 cells. The level of hST6Gal I product on cell surface was examined by flow cytometry analysis. Luciferase reporter plasmids with 5’-deleted constructs and mutants of the hST6Gal I promoter were transiently transfected into HCT116 cells, and the luciferase activity was measured after treatment with curcumin. Results Curcumin led to significant transcriptional repression of the hST6Gal I promoter. Promoter analysis using deletion mutants proved that the − 303 to − 189 region of the hST6Gal I promoter is required for transcriptional repression in response to curcumin. Among putative binding sites for transcription factors IK2, GATA1, TCF12, TAL1/E2A, SPT, and SL1 in this region, by site-directed mutagenesis analysis the TAL/E2A binding site (nucleotides − 266/− 246) was proved to be crucial for curcumin-triggered downregulation of hST6Gal I transcription in HCT116 cells. The transcription activity of hST6Gal I gene in HCT116 cells was markedly suppressed by compound C, an AMP-activated protein kinase (AMPK) inhibitor. Conclusion These indicate that gene expression of hST6Gal I in HCT116 cells is controlled through AMPK/TAL/E2A signal pathway.

Detection of skeletal muscle metastasis: torso FDG PET-CT versus contrast-enhanced chest or abdomen CT

So, Young,Yi, Jeong Geun,Song, Inyoung,Lee, Won Woo,Chung, Hyun Woo,Park, Jeong Hee,Moon, Sung Gyu Acta Radiologica 2015 Acta radiologica Vol.56 No.7

Prediction of the Clinical Outcome of Pediatric Moyamoya Disease With Postoperative Basal/Acetazolamide Stress Brain Perfusion SPECT After Revascularization Surgery

So, Young,Lee, Ho-Young,Kim, Seung-Ki,Lee, Jae Sung,Wang, Kyu-Chang,Cho, Byung-Kyu,Kang, Eunjoo,Lee, Dong Soo Ovid Technologies Wolters Kluwer -American Heart A 2005 Stroke Vol.36 No.7

<P>BACKGROUND AND PURPOSE: We evaluated whether basal/acetazolamide stress brain perfusion SPECT performed after revascularization surgery can predict the further clinical outcome of patients with pediatric moyamoya disease. METHODS: A total of 77 (31 males, 46 females, age 6.6+/-3.2 years) patients with postoperative pediatric moyamoya disease who underwent basal/acetazolamide stress brain perfusion SPECT 6 to 12 months after revascularization surgery and who were followed-up >12 months after SPECT were included. Mean follow-up period after SPECT was 36+/-19 months. Sixty-two patients underwent bilateral ribbon encephaloduroarteriosynangiosis (EDAS), 14 bilateral EDAS, and 1 unilateral EDAS. Ordinal logistic regression analysis using 5 independent variables (infarction on preoperative MRI, age at the first operation, highest Suzuki stage on cerebral angiography, and regional cerebrovascular reserve on postoperative SPECT) against postoperative clinical outcomes was performed. RESULTS: Fifty-one patients had preserved reserve on postoperative SPECT and their clinical outcomes were excellent (30), good (15), fair (4), and poor (2); 26 patients had decreased reserve (excellent, 1; good, 7; fair, 14; poor, 4). On ordinal logistic regression analysis, age at the first operation (P=0.033) and reserve on postoperative SPECT (P<0.001) were statistically significant. CONCLUSIONS: Basal/acetazolamide stress brain perfusion SPECT performed at 6 to 12 months after the indirect bypass operation could predict the further clinical outcome of pediatric patients with moyamoya disease. Patients with decreased cerebrovascular reserve will have remaining neurological deficit and ischemic attacks on follow-up.</P>

Spatial and Temporal Politics of Memories: Focusing on Shepard’s Fool for Love

( Yoon¸ So Young ) 동국대학교 영어권문화연구소 2018 영어권문화연구 Vol.11 No.2

Well-known for a prolific writer, Shepard won a variety of awards. Shepard’s theatrical techniques are particular and salient to investigate. The West is one of his recurring themes, which are focused on American identity, American-ness, American fathers’ masculinity as well. Sam Shepard as a successor to tradition of American plays embodies his peculiar realism on the stage, his theatrical techniques sums up representation of using real props, immediacy and transformation techniques. His Family Trilogy and Family Plays are representative ones to show his theatricalism. This study investigates Sam Shepard's Fool for Love, which belongs to his Family Plays. Its main focus is on spatial division and temporal reversal with a view of incestuous relationships between siblings. This stage has conscious and subconscious spaces which are revealed by dividing characters’ areas onstage. Among them, women's space seems relatively empty like the picture the Old Man pointed out. There certainly exists May, but there is no room for their mothers despite providing their father’s space. Moreover, the father figure shows authorities to cross the border between reality and fantasy. In particular, the Old Man’s utterance has control over Eddie. Memories of the characters onstage are connected to passage of time; especially to show the Old Man’s past duality. For that reason, Eddie and May are inseparably stuck in rhetorical topography of love. Therefore, their foolishness for love is about the Old Man’s dual life with his two families. Like a quote by Archbishop Anthony Bloom, “The proper response to love is to accept it. There is nothing to do.”

잠재계층분석을 통한 스토킹행위의 유형 분류: 경범죄 처벌법상 지속적 괴롭힘을 중심으로

강소영 ( Kang¸ So Young ),김한솔 ( Kim¸ Han Sol ) 한국경찰학회 2021 한국경찰학회보 Vol.23 No.5

이 연구는 스토킹행위를 기존의 개별 유형 분류와 달리, 다중 또는 중첩된 행위들을 유형화하여 그 특성을 살펴보고자 하였다. 이를 위해, 2013년부터 2021년 6월까지 경범죄 처벌법상 지속적 괴롭힘으로 유죄판결을 받은 1심 판결문 자료를 제정 스토킹처벌법상 행위 유형과 연계 분류하여, 잠재계층분석(LCA)을 통해 유형화하고, 그 특성을 분석하였다. 분석 결과, 스토킹행위는 배회형, 점진형, 감시형으로 분류되었다. 배회형은 피해자 주변을 배회하면서 두 가지 이상의 행위가 중첩되는 유형으로 나타났다. 점진형은 주로 찾아가는 행위를 시도하지만, 점진적으로 침입범죄를 저지를 확률이 높은 유형으로 관찰되었다. 감시형은 주로 미행하고 지켜보는 등 소극적인 행위처럼 보이지만, 다른 유형에 비해 중첩된 행위가 가장 많은 유형으로 분석되었다. 이 논문이 경범죄의 판례를 통해 제한된 정보만으로 분석한 것은 한계가 있으나, 그간 피해자와의 관계만을 중심으로만 분석되었던 것과 달리 행위 중심의 유형화를 도출했다는 점에서는 의의가 있다. In this study, we tried to examine the types and characteristics by categorizing the stalking behavior shown in the judgment. From 2013 to June 2021, stalking behavior was variableized, classified through latent class analysis (LCA) and analyzed the characteristics of each type. As a result of the classification, stalking behavior was classified into shadowing type, gradual type, and surveillance type. The shadowing type wandering around the victim. It was a type of behavior before attempting direct contact with the victim. Gradual type was observed as a type with visiting victim-related places, knocking on the door and attempting to invade. The surveillance type showed passive behavior such as following and watching the victim. But it was likely to develop into a gradual type. This study attempted to categorize and analyze its characteristics by analyzing an actual stalking behavior. In particular, it is meaningful that it can provide basic data necessary for supplementing the enactment law.