Author divided 60 patients who got lower abdomen or lower extremity surgical operation into three groups. Each group consisted of 20 patients. We injected ketaimine 10mg, 20mg and 30mg respectively into the epidural space when the patient complained o...
Author divided 60 patients who got lower abdomen or lower extremity surgical operation into three groups. Each group consisted of 20 patients. We injected ketaimine 10mg, 20mg and 30mg respectively into the epidural space when the patient complained of pain postoperatively and observed the postoperative analgesic effect of ketamine. Finally, we concluded the following :
1) The onset time of analgesic effect
: The analgesic effect appeared within 10 minutes in 3 groups and the significant. difference among them was not seen.
2) The duration of analgesic effect
; The duration of analgesia was relatively short with less than 1 hour on an average in all 3 groups and was not constant.
3) Cardiopulmonary system
; The significant change of blood pressure, pulse and respiratory rate was not seen in all three groups and the difference among them also was not seen.
4) Side effects
; Sedative action(16%), nausea(10%), dizziness(5%), headache(3.3%) From above results, the epidural administration of ketamine is not suitable for postoperative pain management because of a lot of side effects as well as short and inconstant duration of analgesic effect.