인공우식병소의 재광화 탐지를 위한 크세논 광의 활용 = Detection of remineralization of artificial incipient carious lesions using xenon light

다국어 초록 (Multilingual Abstract)

Purpose: The purpose of this study was to evaluate the effectiveness of 325 ㎚ xenon light in the detection of the early dental caries lesion by promotion of remineralization of subsurface lesion of the tooth enamel in vitro.
Methods: Sixty-five 3×3 ㎜ bovine incisors were separated into five groups and demineralized at decalcifying solution (pH 5.0) for 12, 24, 48 and 72 hrs to prepare of early artificial caries lesions and compared with the control (n=13) stored into the saline. After all samples were treated remineralazed for 14 days. Surface changes were characterized with microhardness tester. Characteristics of fluorescence were measured using the DIAGNOdent, the Optical multichannel analyzer (OMA) with xenon light and confocal laser scanning microscopy (CLSM).
Results: After remineralization, the range lesion depth of enamel by CLSM was approximately recovered 20-30 ㎛. According to OMA analysis, the specimen exhibited apparent reduction of 425 ㎚ peak as demineralization was progressed from control to 72 hrs. The slope of 450-550 ㎚ also significantly decreased as demineralization progressed. When we considered the correlation among all variables, there was a highly significant correlation between lesion depth and highest peak and value of slope by 325 ㎚ of xenon light as UV laser's. Comparison of the highest peak (425 ㎚) and slope value (450-550 ㎚) by 325 ㎚ of xenon light between the de-and remineralization has shown effectiveness on the determination of the subsurface change.
Conclusion: Since 325 ㎚ xenon light was sensitive enough to differentiate the minor changes of the enamel, it may have a high potential in the detection of promotion of remineralization of the incipient carious lesions.

목차 (Table of Contents)

• I. 서론 1
• 1. 연구배경 1
• 2. 연구목적 7
• II. 연구 재료 및 방법 8
• 1. 시편제작 및 초기 우식법랑질 형성 8
• 2. 재광화를 위한 시편의 pH 순환처리 10
• 3. 표면미세경도 측정 11
• 4. 분광학적 특성 관찰 12
• 5. 공초점주사현미경을 사용한 탈회양상 관찰 14
• 6. 자료처리 15
• III. 성적 16
• 1. 절단면의 탈회깊이 관찰 16
• 2. 표면미세경도 측정 17
• 3. 분광학적 특성 분석 18
• IV. 고찰 23
• V. 결론 29
• 참고문헌 31
• Abstract 37