돌발성 난청 환자의 한의 집중치료 효과 분석 및 현훈이 예후에 미치는 영향

다국어 초록 (Multilingual Abstract)

Purpose :
This study aimed to retrospectively analyze the clinical characteristics and therapeutic effectiveness of Korean medicine reatment in patients with sudden sensorineural hearing loss (SSNHL) who showed delayed recovery after steroid therapy. Additionally, we analyzed the influence of vertigo on treatment outcomes.
Methods :
We retrospectively analyzed the medical records of patients treated at the Department of Korean Medicine Ophthalmology, Otolaryngology & Dermatology at Daejeon Korean Medicine Hospital of Daejeon University from January 1, 2022, to September 30, 2025. A total of 33 patients who met the inclusion criteria were selected for the analysis. Most patients had previously received standard Western treatment, including systemic or intratympanic steroids. Korean medicine treatment included herbal medicine, acupuncture, and moxibustion. Therapeutic effectiveness was evaluated by comparing pure tone audiometry (PTA) thresholds between the start and end of treatment, and recovery rates were assessed based on Siegel’s criteria. The statistical analysis was performed using Python ver 3.10 and SciPy library.
Results :
1. The average age of the subjects was 43.6 ± 15.6 years, and the median interval from onset to treatment was 12.0 days. Notably, 90.9% patients had a history of combined systemic and intratympanic steroid therapy before visiting the Korean medicine hospital.
2. The mean PTA threshold significantly improved from 52.88 ± 20.31㏈ at the start of treatment to 42.73 ± 19.34㏈ at the end of treatment (p< 0.001).
3. According to Siegel’s criteria, the overall recovery rate was 45.5%, with 36.4% showing complete recovery.
4. Patients with vertigo (n=14) showed higher initial PTA thresholds (60.36 ± 25.11㏈) compared to those without vertigo (n=19, 50.39 ±16.08 ㏈), although the difference was not statistically significant (p =0.175). Furthermore, there was no significant difference in the degree of hearing improvement between the two groups (10.18 ± 12.18㏈ vs. 10.13 ± 13.03㏈, p = 0.992).
Conclusion :
Intensive Korean medicine treatment showed significant therapeutic effectiveness in patients with SSNHL, even in those who showed delayed recovery after steroid therapy. Notably, patients with vertigo achieved comparable hearing improvement to those without vertigo, despite having worse initial hearing levels. These findings suggest that intensive Korean medicine treatment can be a useful salvage treatment strategy for patients with delayed recovery from SSNHL.

목차 (Table of Contents)

• Ⅰ. 서 론 01
• Ⅱ. 연구 방법 03
• 1. 연구 기간 및 연구 대상 03
• 2. 연구 방법 04
• 3. 윤리적 승인 06
• 4. 통계 분석 방법 07
• Ⅲ. 결 과 08
• 1. 연구 대상자의 일반적 특성 08
• 2. 한의 집중치료의 임상적 효과 11
• 1) 청력 역치의 변화 11
• 2) Siegel’s criteria에 따른 회복률 12
• 3. 예후 인자에 따른 치료 효과 분석 13
• Ⅳ. 고 찰 14
• Ⅴ. 결 론 18
• 참 고 문 헌 19
• 영 문 초 록 25