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      KCI등재

      항암화학 치료를 통해 병리학적 완전 관해에 이른 절제 불가능한 국소 진행성 간내담관암 = Pathologic Complete Remission in a Patient with Locally Advanced Unresectable Intrahepatic Cholangiocarcinoma Treated with Chemotherapy

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      https://www.riss.kr/link?id=A104221918

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      다국어 초록 (Multilingual Abstract)

      A 54-year-old female with postprandial dyspepsia and abdominal pain was diagnosed as locally advanced unresectable intrahepatic cholangiocarcinoma by radiologic imaging studies resulting in invasion to bilateral main bile duct and right portal vein. The patient underwent extended right hepatectomy and portal vein resection after gemcitabine and cisplatin combined chemotherapy for a total of 40 cycles after the diagnosis. Final pathology showed, followed by pathological complete remission, without any residual cancer cell. The patient has survived for over 6 years without any evidence of recurrence. This case suggests that locally advanced intrahepatic cholangiocarcinoma, which can’t be resected, was also proved to be capable of pathological complete remission with active chemotherapy, and long-term survival could be achieved. Therefore, active multidisciplinary approach and patient-oriented treatments using various methods should be considered for locally advanced unresectable intrahepatic cholangiocarcinoma.
      Korean J Pancreas Biliary Tract 2017;22(4):188-192
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      A 54-year-old female with postprandial dyspepsia and abdominal pain was diagnosed as locally advanced unresectable intrahepatic cholangiocarcinoma by radiologic imaging studies resulting in invasion to bilateral main bile duct and right portal vein. T...

      A 54-year-old female with postprandial dyspepsia and abdominal pain was diagnosed as locally advanced unresectable intrahepatic cholangiocarcinoma by radiologic imaging studies resulting in invasion to bilateral main bile duct and right portal vein. The patient underwent extended right hepatectomy and portal vein resection after gemcitabine and cisplatin combined chemotherapy for a total of 40 cycles after the diagnosis. Final pathology showed, followed by pathological complete remission, without any residual cancer cell. The patient has survived for over 6 years without any evidence of recurrence. This case suggests that locally advanced intrahepatic cholangiocarcinoma, which can’t be resected, was also proved to be capable of pathological complete remission with active chemotherapy, and long-term survival could be achieved. Therefore, active multidisciplinary approach and patient-oriented treatments using various methods should be considered for locally advanced unresectable intrahepatic cholangiocarcinoma.
      Korean J Pancreas Biliary Tract 2017;22(4):188-192

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      참고문헌 (Reference)

      1 Shaib Y, "The Epidemiology of Cholangiocarcinoma" 24 : 115-125, 2004

      2 Jordan E, "Systemic therapy for biliary cancers" 5 : 65-, 2016

      3 Cunningham SC, "Palliation of hepatic tumors" 16 : 277-291, 2007

      4 Patel T, "Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States" 33 : 1353-1357, 2001

      5 Lee J, "Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, openlabel, randomised, phase 3 study" 13 : 181-188, 2012

      6 Esnaola NF, "Evaluation and management of intrahepatic and extrahepatic cholangiocarcinoma" 122 : 1349-1369, 2016

      7 Valle J, "Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer" 362 : 1273-1281, 2010

      8 Brandi G, "Cholangiocarcinoma:current opinion on clinical practice diagnostic and therapeutic algorithms: a review of the literature and a long-standing experience of a referral center" 48 : 231-241, 2016

      9 Weatherly J, "Chemotherapy outcomes for the treatment of unresectable intrahepatic and hilar cholangiocarcinoma: a retrospective analysis" 29 (29): 271-, 2011

      10 Khan SA, "Changing international trends in mortality rates for liver, biliary and pancreatic tumours" 37 : 806-813, 2002

      1 Shaib Y, "The Epidemiology of Cholangiocarcinoma" 24 : 115-125, 2004

      2 Jordan E, "Systemic therapy for biliary cancers" 5 : 65-, 2016

      3 Cunningham SC, "Palliation of hepatic tumors" 16 : 277-291, 2007

      4 Patel T, "Increasing incidence and mortality of primary intrahepatic cholangiocarcinoma in the United States" 33 : 1353-1357, 2001

      5 Lee J, "Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, openlabel, randomised, phase 3 study" 13 : 181-188, 2012

      6 Esnaola NF, "Evaluation and management of intrahepatic and extrahepatic cholangiocarcinoma" 122 : 1349-1369, 2016

      7 Valle J, "Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer" 362 : 1273-1281, 2010

      8 Brandi G, "Cholangiocarcinoma:current opinion on clinical practice diagnostic and therapeutic algorithms: a review of the literature and a long-standing experience of a referral center" 48 : 231-241, 2016

      9 Weatherly J, "Chemotherapy outcomes for the treatment of unresectable intrahepatic and hilar cholangiocarcinoma: a retrospective analysis" 29 (29): 271-, 2011

      10 Khan SA, "Changing international trends in mortality rates for liver, biliary and pancreatic tumours" 37 : 806-813, 2002

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2024 평가예정 재인증평가 신청대상 (재인증)
      2021-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2019-03-14 학회명변경 한글명 : 대한췌담도학회 -> 대한췌장담도학회 KCI등재후보
      2019-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
      2018-12-01 평가 등재후보 탈락 (계속평가)
      2016-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0 0 0
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
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