Background:
I have assessed the effect of intravenous induction agents on intubation conditions and hemodynamic changes when using rocuronium 0.7 mg/kg for rapid sequence induction.
Methods:
Sixty ASA class I or II patients undergoing elective surgery...
Background:
I have assessed the effect of intravenous induction agents on intubation conditions and hemodynamic changes when using rocuronium 0.7 mg/kg for rapid sequence induction.
Methods:
Sixty ASA class I or II patients undergoing elective surgery were divided into thiopental group (5 mg/kg, n=20), propofol group (2 mg/kg, n=20) and etomidate group (0.2 mg/kg, n=20). Anesthesia was induced with intravenous induction agents. After loss of consciousness, rocuronium 0.7 mg/kg was injected. Intubation was attempted at 60 seconds after rocuronium had been given. Arterial blood pressure and heart rate were measured before induction, immediately after intubation, 1 minute, 3 minutes, 5 minutes and 10 minutes after intubation. Intubation condition was assessed by jaw relaxation, vocal cord movement, response to tracheal intubation and evaluated as excellent, good, fair and poor.
Results:
Excellent intubation conditions were obtained 55%(n=11) in the thiopental group, 60%(n=12) in the propofol group and 45%(n=9) in the etomidate group. Systolic and diastolic arterial blood pressure were increased after intubation in all three groups. But these changes were minimal after propofol.
Conclusions:
There was no statistically significant difference on intubation conditions after intravenous injection of thiopental 5 mg/kg, propofol 2 mg/kg and etomidate 0.2 mg/kg when using rocuronium 0.7 mg/kg for rapid sequence induction.