http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hyungkun Yoon,Dong Jae Oh,Ho-Suk Suh,Kyoung-Uk Lee,Se-Won Lim,Jun-Yeob Lee,Jong-Chul Yang,이재헌,Juwon Ha,Bun-Hee Lee,강승걸,Ho-Kyoung Yoon,Jihyun Moon,Seung-Min Bae,Youngdo Kwon,Hyun-Chung Kim,Kang Seob Oh 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.2
Objective The aim of the present study was to provide clinical consensus and evidence regarding initial treatment strategies for the pharmacological treatment of social anxiety disorder (SAD) in Korea. Methods We prepared a questionnaire to derive a consensus from clinicians regarding their preference for the pharmacological treatment of SAD in Korea. Data regarding medication regimens and psychotropic drugs used during initial treatment, the doses used, and the pharmacological treatment duration were obtained. Responses were obtained from 66 SAD experts, and their opinions were classified into three categories (first-line, second-line, third-line) using a chi-square analysis. Results Clinicians agreed upon first-line regimens for SAD involving monotherapy with selective serotonin reuptake inhibitors (SSRIs) or the serotonin-norepinephrine reuptake inhibitor (SNRI) venlafaxine, or combined therapy using antidepressants with betablockers or benzodiazepines on a standing or as-needed basis. First-line psychotropic drug choices for initial treatment included the following: escitalopram, paroxetine, sertraline, venlafaxine, and propranolol. The medication dosage used by domestic clinicians was found to be comparable with foreign guidelines. Domestic clinicians tended to make treatment decisions in a shorter amount of time and preferred a similar duration of maintenance treatment for SAD when compared with foreign clinicians. Conclusion This study may provide significant information for developing SAD pharmacotherapy guidelines in Korea, especially in the early stage of treatment.
Son, Yoon Jun,Kang, Jin Soo,Yoon, Jungjin,Kim, Jin,Jeong, Juwon,Kang, Jiho,Lee, Myeong Jae,Park, Hyun S.,Sung, Yung-Eun American Chemical Society 2018 The Journal of Physical Chemistry Part C Vol.122 No.13
<P>Dye-sensitized solar cells (DSSCs) are highly efficient and reliable photovoltaic devices that are based on nanostructured semiconductor photoelectrodes. From their inception in 1991, colloidal TiO<SUB>2</SUB> nanoparticles (NPs) with the large surface area have manifested the highest performances and the particle size of around 20 nm is generally regarded as the optimized condition. However, though there have been reports on the influences of particle sizes in conventional DSSCs employing iodide redox electrolyte, the size effects in DSSCs with the state-of-the-art cobalt electrolyte have not been investigated. In this research, systematic analyses on DSSCs with cobalt electrolytes are carried out by using various sizes of NPs (20-30 nm), and the highest performance is obtained in the case of 30 nm sized TiO<SUB>2</SUB> NPs, indicating that there is a reversed power conversion efficiency trend when compared with those with the iodide counterpart. Detailed investigations on various factors-light harvesting, charge injection, dye regeneration, and charge collection-reveal that TiO<SUB>2</SUB> particles with a size range of 20-30 nm do not have a notable difference in charge injection, dye regeneration, and even in light-harvesting efficiency. It is experimentally verified that the superior charge collection property is the sole origin of the higher performance, suggesting that charge collection should be prioritized for designing nanostructured TiO<SUB>2</SUB> photoelectrodes for DSSCs employing cobalt redox electrolytes.</P> [FIG OMISSION]</BR>
Effective cryopreservation method by controlling the clump size of human embryonic stem cells
Juwon Jung,Hye Won Seol,Jin Ah Baek,Bo Ae Yoon,Hee-Sun Kim,Sun Kyung Oh,Seung-Yup Ku,Seok Hyun Kim,Shin Yong Moon,Young Min Choi 한국발생생물학회 2011 한국발생생물학회 학술발표대회 Vol.30 No.-
Human embryonic stem cells (hESCs) have the potential for use in regenerative medicine and in the field of basic research. Therefore, effective cryopreservation and storage of hESCs are important for preservation of newly established cell line for various purposes. Despite poor survival and slow recovery after thawing, the conventional slow freezing method is most commonly used for cryopreservation of hESCs due to its simplicity and ease of use for freezing a large number of hESCs appropriate to clinical applications. Here we controlled the clump size (Group Ⅰ; 400~450 ㎛, Group Ⅱ; 800~900 ㎛, and Group Ⅲ; 1500~1700 ㎛) of hESCs at 5 days after plating using a glass pipette during cryopreservation in order to obtain a larger amount of hESCs after thawing. Attachment rates differed significantly (P<0.05) in each of the three groups and the average of attachment rate of GroupⅡ was highest in SNUhES4 and H1. In particular, the attachment rate of Group Ⅱ in SNUhES3 showed a significant improvement with ROCK inhibitor Y-27632. These results indicate that clump size and cell-cell adhesions of GroupⅡ are appropriate for cryopreservation compared to the Group Ⅰ and Group Ⅲ. This method increased cell viability and reduced the recovery time leading to various experiments, and therefore has an advantage for use with hESCs like newly established in particular. We demonstrated that use of this effective cryopreservation method with control of the clump size of hESCs can effectively improve the attachment rate and survival of post-thaw hESCs with and without Y-27632.