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RISS 인기검색어
- 검색키워드
- 저자 : Vinay Tomar (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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Sher Singh Yadav,Vivek Kumar Singh,Vinay Tomar,Neeraj Agarwal,Anil Gulani 대한비뇨의학회 2018 Investigative and Clinical Urology Vol.59 No.3
Purpose: To report our initial experience with urethral reconstruction using a combined dorsal lingual mucosal graft (LMG) and ventral onlay preputial flap for long obliterative or near-obliterative strictures in circumcised patients. Materials and Methods: This was a retrospective study of 10 patients from January 2015 to June 2017 with long obliterative or near-obliterative anterior urethral strictures and circumcised prepuces. All patients underwent a combined approach using a dorsally LMG and a narrow preputial onlay flap ventrally to create a 26–30 Fr. neourethra over a 14-Fr Foley catheter. Success was defined as no requirement for additional urethral instrumentation. The follow-up period ranged from 6 to 32 months. Results: The patients ranged in age from 17 to 44 years (mean, 32.3±9.59 years) and stricture length ranged from 9 to 12.5 cm (mean, 10.77±1.15 cm). Four strictures were obliterative and six were near-obliterative. Two patients had a history of prior urethroplasty. The length of the LMGs harvested ranged from 11 to 14 cm (mean, 12.8±1.03 cm). The preputial flaps available were from 1 to 1.5 cm in width (1.29±0.16 cm) and the desired length. Maximum urinary flow rate (Qmax) achieved ranged from 12 to 26 mL/s (mean, 20.46±3.71 mL/s) after 3 months. One patient needed a single direct visualized internal urethrotomy and another patient develop temporary superficial penile necrosis. The success rate was 90%. Conclusions: Long obliterative and near-obliterative penile and penobulbar urethral strictures can still be treated in circumcised patients using available preputial skin along with lingual mucosa with good outcomes.
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Goto Gangkak,Rohit Bhattar,Alka Mittal,Sher Singh Yadav,Vinay Tomar,Ajay Yadav,Jayanti Mehta 대한비뇨의학회 2017 Investigative and Clinical Urology Vol.58 No.2
Purpose: Estrogens act through interaction with 2 receptor subtypes, ER alpha (ERα) and ER beta (ERβ), in human prostate. The aim of the present study was to semiquantitatively assess the differential expression of ER subtypes in human benign prostatic hyperplasia (BPH) by use of immunocytochemistry (IHC) methods and to explore their relationship with various measures of BPH. Materials and Methods: A total of 45 patients with BPH undergoing transurethral resection of the prostate and 22 patients with bladder cancer with normal prostate undergoing surveillance cystoscopy were studied as cases and controls, respectively. Quantitative immunolabeling of ER subtypes was scored by use of a semiquantitative scale. Also, correlations were assessed between ER levels in prostate and various measures of BPH. Results: Overall, we found strong immunostaining for ERα in stroma and for ERβ in epithelium, respectively. The IHC score for ERα differed significantly between BPH patients and controls in both stroma (p≤0.001) and epithelium (p=0.008), respectively. The ERβ IHC score was also significantly higher in the epithelium of BPH patients (p=0.01). Also, we found a significant correlation between prostatic ER levels and various clinical measures of BPH. Conclusions: ERs may play an important role in the pathogenesis of BPH.
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Bajaj, Bharat,Joh, Han I.,Jo, Seong M.,Kaur, Gurpreet,Sharma, Anjali,Tomar, Monika,Gupta, Vinay,Lee, Sungho The Royal Society of Chemistry 2016 Journal of Materials Chemistry B Vol.4 No.2
<P>Electrospun carbon nanofibers (CNFs) decorated with copper oxide nanoparticles were successfully synthesized using a one step and modified hydroxyl ion assisted alcohol reduction method. The X-ray diffraction pattern reveals the presence of (−111), (111) and (−202) crystal planes of monoclinic copper oxide (CuO). The CuO coated CNF air annealed at 250 °C exhibited an electrical conductivity of 251 S m<SUP>−1</SUP>. The CuO coated CNFs were employed as a novel flexible matrix for a cholesterol biosensor. The biosensor exhibited a high sensitivity of 75 μA mM<SUP>−1</SUP> cm<SUP>−2</SUP> over the linear range (0.12 mM to 12.93 mM) of cholesterol. This coating method offers easy and inexpensive processing with a flexible and robust supporting structure for biosensing applications.</P>
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