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Machine Learning Approaches for Anticancer Peptide Discovery: A Comprehensive Review
Priya Dharshini 조선대학교 기초과학연구원 2023 조선자연과학논문집 Vol.16 No.4
Invasive species are organisms that are introduced into places outside of their natural distribution range. The global pet trade is facilitating the introduction of invasive species into new countries and areas. Among the introduced alien species, turtles are one of the most common animal groups whether lives in wetland ecosystems, such as wetlands or reservoirs. Like other countries around the world, exotic turtles is becoming a growing concern for the wetland ecosystem in South Korea. In this study, we report new reports of subspecies of Painted turtle (Chrysemys spp.): Chrysemys picta marginata, C. p. bellii and C. dorsalis, from the reservoirs in downtown Cheongju and Gwangju, South Korea. We used morphological features, such as the characteristics of the legs, plastron, and carapace, to identify the turtles. It is assumed that all turtles were artificially released into nature. Considering the increasing number of reports on the introduction of alien invasive turtles in Korean wetlands, we recommend the formulation of an immediate and systematic management plan for pet trades and organized continuous monitoring programs.
Priyadharshini, R. Mythili,Ramanujam, N.,Valanarasu, T. The Korean Society for Computational and Applied M 2010 Journal of applied mathematics & informatics Vol.28 No.5
We consider a mixed type singularly perturbed one dimensional elliptic problem with discontinuous source term. The domain under consideration is partitioned into two subdomains. A convection-diffusion and a reaction-diffusion type equations are posed on the first and second subdomains respectively. Two hybrid difference schemes on Shishkin mesh are constructed and we prove that the schemes are almost second order convergence in the maximum norm independent of the diffusion parameter. Error bounds for the numerical solution and its numerical derivative are established. Numerical results are presented which support the theoretical results.
Priyadharshini, R. Mythili,Ramanujam, N. The Korean Society for Computational and Applied M 2009 Journal of applied mathematics & informatics Vol.27 No.3
In this paper, a singularly perturbed reaction-convection-diffusion problem with two parameters is considered. A parameter-uniform error bound for the numerical derivative is derived. The numerical method considered here is a standard finite difference scheme on piecewise-uniform Shishkin mesh, which is fitted to both boundary and initial layers. Numerical results are provided to illustrate the theoretical results.
HYBRID DIFFERENCE SCHEMES FOR A SYSTEM OF SINGULARLY PERTURBED CONVECTION-DIFFUSION EQUATIONS
Priyadharshini, R.Mythili,Ramanujam, N.,Tamilselvan, A. The Korean Society for Computational and Applied M 2009 Journal of applied mathematics & informatics Vol.27 No.5
In this paper, two hybrid difference schemes on the Shishkin mesh are constructed for solving a weakly coupled system of two singularly perturbed convection-diffusion second order ordinary differential equations with a small parameter multiplying the highest derivative. We prove that the schemes are almost second order convergence in the supremum norm independent of the diffusion parameter. Error bounds for the numerical solution and its derivative are established. Numerical results are provided to illustrate the theoretical results.
( Priyadharshini Pachiappan ),( Mahalingam C Aruchamy ),( Shashidhar Kaluvarahalli Ramanna ) 한국잠사학회 2009 International Journal of Industrial Entomology Vol.18 No.1
An in vitro and in vivo studies were conducted to evaluate the antibacterial efficacy of certain botanicals viz., rhizomes of turmeric (Curcuma longa) and leaves of amla (Phyllanthus emblica), asparagus (Asparagus racemosus), bael (Aegle marmelos), boerhavia (Boerhavia diffusa), garlic (Allium sativum) and basil (Oscimum basicilum) against bacterial pathogens viz., Staphylococcus sp., Bacillus sp. and Klebsiella cloacae, of silkworm, Bombyx mori. Asparagus and basil, amla and boerhavia, basil and bael at concentration of 20,000 ppm showed higher antibacterial activity against Staphylococcus sp., Bacillus sp., K. cloacae respectively, both in vitro and in vivo studies.
Repeated Random Mutagenesis of α-Amylase from Bacillus Licheniformis for Improved pH Performance
( Ramachandran Priyadharshini ),( Shankar Manoharan ),( Devaraj Hemalatha ),( Paramasamy Gunasekaran ) 한국미생물 · 생명공학회 2010 Journal of microbiology and biotechnology Vol.20 No.12
The α-amylases activity was improved by random mutagenesis and screening. A region comprising residues from the position 34-281 was randomly mutated in B. licheniformis α-amylase (AmyL), and the library with mutations ranging from low, medium, and high frequencies was generated. The library was screened using an effective liquid-phase screening method to isolate mutants with an altered pH profile. The sequencing of improved variants indicated 2-5 amino acid changes. Among them, mutant TP8H5 showed an altered pH profile as compared with that of wild type. The sequencing of variant TP8H5 indicated 2 amino acid changes, Ile157Ser and Trp193Arg, which were located in the solvent accessible flexible loop region in domain B.
( Ramachandran priyadharshini ),( Ngoc Phuong Thao Nguyen ),( Joon Ho Choi ),( Yun Chan Kang ),( Marimuthu Jeya ),( Jung Kul Lee ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.3
A high β-glucosidase (BGL)-producing strain, Stereum hirsutum, was identified and isolated and showed a maximum BGL activity (10.4 U/ml) when cultured with Avicel and tryptone as the carbon and nitrogen sources, respectively. In comparison with other BGLs, BGL obtained from S. hirsutum showed a higher level of activity to cellobiose (Vmax = 172 U/mg, and kcat = 281/s). Under the optimum conditions (600 rpm, 30oC, and pH 6.0), the maximum BGL activity of 10.4 U/ml with the overall productivity of 74.5 U/l/h was observed. BGL production was scaled up from a laboratory scale (7-L fermenter) to a pilot scale (70-L fermenter). When S. hirsutum was cultured in fed-batch culture with rice straw as the carbon source in a 70-L fermenter, a comparable productivity of 78.6 U/l/h was obtained. Furthermore, S. hirsutum showed high levels of activity of other lignocellulases (cellobiohydrolase, endoglucanase, xylanase, and laccase) that are involved in the saccharification of biomasses. Application of S. hirsutum lignocellulases in the hydrolysis of Pinus densiflora and Catalpa ovata showed saccharification yields of 49.7% and 43.0%, respectively, which were higher than the yield obtained using commercial enzymes.