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- 저자 : Patrick KLAP (검색결과 1 건)
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OROMANDIBULAR DYSTONIA: DEMOGRAPHICS AND CLINICAL DATA FROM 240 PATIENTS
Linda SLAIM,Myriam COHEN,Patrick KLAP,Marie VIDAILHET,Alain PERRIN,Daniel BRASNU,Denis AYACHE,Marie MAILLY 대한파킨슨병및이상운동질환학회 2018 Journal Of Movement Disorders Vol.11 No.2
Objective: to report demographic data from a large cohort of patients with oromandibular dystonia (OMD). Methods: This is a retrospective review of patients with OMD referred to our institution, between 1989 and 2015. Demographic (age of onset, sex, familial history of dystonia) and clinical (type of OMD, associated dystonia, etiology of dystonia) data were collected from a cohort of 240 individuals. Results: The mean age of onset was 51.6 year-old, with a female predominance (2:1). A family history of dystonia was found in 6 patients (2.5%). One hundred and forty nine patients (62.1%) had the jaw-opening OMD; 48 patients (20.0%) had the jaw-closing type, and 43 patients (17.9%) had mixed OMD; 64 patients (26.7%) had associated lingual dystonia. Eighty-two patients (34.2%) had a focal dystonia, 131 patients (54.6%) had segmental dystonia, and 27 patients (11.3%) had generalized dystonia. One hundred and seventy one patients (71.3%) had idiopathic OMD. Conclusions: OMD is a chronic, disabling focal dystonia. Our study finds a female prevalence, onset in middle age and mostly idiopathic etiology. Unlike in other studies, jaw-opening was the most frequent clinical type of OMD.
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