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A machine learning approach for the condition monitoring of rotating machinery†
Dimitrios Kateris,Dimitrios Moshou,Xanthoula-Eirini Pantazi,Ioannis Gravalos,Nader Sawalhi,Spiros Loutridis 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.1
Rotating machinery breakdowns are most commonly caused by failures in bearing subsystems. Consequently, condition monitoring ofsuch subsystems could increase reliability of machines that are carrying out field operations. Recently, research has focused on the implementationof vibration signals analysis for health status diagnosis in bearings systems considering the use of acceleration measurements. Informative features sensitive to specific bearing faults and fault locations were constructed by using advanced signal processingtechniques which enable the accurate discrimination of faults based on their location. In this paper, the architecture of a diagnostic systemfor extended faults in bearings based on neural networks is presented. The multilayer perceptron (MLP) with Bayesian automatic relevancedetermination has been applied in the classification of accelerometer data. New features like the line integral and feature basedsensor fusion are introduced which enhance the fault identification performance. Vibration feature selection based on Bayesian automaticrelevance determination is introduced for finding better feature combinations.
Nutritional Quality Changes of Fresh-cut Tomato during Shelf Life
Maria D.C. Antunes,Daniela Rodrigues,Vasilios Pantazis,Ana M. Cavaco,Anastasios S. Siomos,Graça Miguel 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.5
Effects of dip treatments on nutritional quality preservation during the shelf life of fresh-cut tomato (Licopersicum esculentum Mill.) cv. Eufrates were investigated. Fresh-cut tomatoes were dipped in solutions of 2% ascorbic acid, citric acid, and calcium lactate for 2min, then stored at 4ºC for 20 days. Color (L*, a*, and b*),firmness, ºBrix, phenolics, ascorbic acid content, antioxidant activity (DPPH), and sugars were measured during storage. Pathogen development was monitored, and a sensory evaluation was performed. Ascorbic acid was better in maintaining firmness. No treatments significantly affected ºBrix, color, or sugars. Ascorbic acid maintained a higher antioxidant capacity, phenolics, and ascorbic acid content,and was better at reducing bacterial growth, while citric acid treatment was better at prevention of yeast and molds proliferation. Fresh-cut tomatoes showed good quality after 10 days of shelf life, except for flavor with the calcium lactate treatment. Ascorbic acid treatment better preserved the general and nutritional quality parameters.
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations
Zhang, Yiqun,Kwok-Shing Ng, Patrick,Kucherlapati, Melanie,Chen, Fengju,Liu, Yuexin,Tsang, Yiu Huen,de Velasco, Guillermo,Jeong, Kang Jin,Akbani, Rehan,Hadjipanayis, Angela,Pantazi, Angeliki,Bristow, C Elsevier Science B.V., Amsterdam 2017 CANCER CELL Vol.31 No.6
Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing
Yang, L.,Lee, M.S.,Lu, H.,Oh, D.Y.,Kim, Y.,Park, D.,Park, G.,Ren, X.,Bristow, Christopher A.,Haseley, Psalm S.,Lee, S.,Pantazi, A.,Kucherlapati, R.,Park, W.Y.,Scott, Kenneth L.,Choi, Y.L.,Park, Peter University of Chicago Press [etc.] 2016 American journal of human genetics Vol.98 No.5
<P>Although exome sequencing data are generated primarily to detect single-nucleotide variants and indels, they can also be used to identify a subset of genomic rearrangements whose breakpoints are located in or near exons. Using >4,600 tumor and normal pairs across 15 cancer types, we identified over 9,000 high confidence somatic rearrangements, including a large number of gene fusions. We find that the 50 fusion partners of functional fusions are often housekeeping genes, whereas the 30 fusion partners are enriched in tyrosine kinases. We establish the oncogenic potential of ROR1-DNAJC6 and CEP85L-ROS1 fusions by showing that they can promote cell proliferation in vitro and tumor formation in vivo. Furthermore, we found that similar to 4% of the samples have massively rearranged chromosomes, many of which are associated with upregulation of oncogenes such as ERBB2 and TERT. Although the sensitivity of detecting structural alterations from exomes is considerably lower than that from whole genomes, this approach will be fruitful for the multitude of exomes that have been and will be generated, both in cancer and in other diseases.</P>