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        Study of compounds, cytotoxicity and biological activities of essential oil of Satureja rechingeri Jamzad

        Mitra Arman,Kiana Pirian,Mostafa Alinaghizadeh,Fatemeh Khosheghbal,Reza Nahavandi,Saeid Tamadoni Jahromi 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.4

        Nowadays, the essential oil has received a special position for the treatment of diseases. Although Satureja rechingeri Jamzad is an endemic species of Iran, unfortunately few studies have been conducted on its biological properties. In this study, along with the analysis of the compounds of Satureja rechingeri essential oil, cytotoxic, antioxidant and antibacterial properties of the essential oil of this species were investigated. The compounds of prepared essential oil were analyzed by GC-FID and GC–MS using Clevenger. Disc diffusion and MTT methods were used to determine the antibacterial activity and cytotoxicity of the essential oil, respectively. The antioxidant activity of the essential oil was measured by two methods of reducing power assay and DPPH free radical scavenging. p-Cymene (46.5%) was the most identified compound in the essential oil. The essential oil showed higher inhibitory effect on seven bacterial strains relative to the standard antibiotics. The studied essential oil showed significant concentration-dependent inhibitory effect on four cancer cells of Vero, SW480, MCF7 and JET3 with 50% lethal effect of 15.6, 125, 15.6 and 250 μg/mL for each line, respectively. The highest adsorption (2.6 nM) was at 500 μg/mL for reducing power assay and 50% free radical inhibition at a concentration of 375 μg/mL for DPPH antioxidant assay. In general, the essential oil of Satureja rechingeri with high antioxidant, antibacterial and anticancer activity can be used as a cheap and affordable natural product in clinical and pharmaceutical fields.

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        Diversity of medicinal plant traditionally used by Baiga tribes in District Umaria, Madhya Pradesh, India

        Mitra Arman 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.4

        The conventional source of medicinal plants is an important way for daily curative uses in rural area throughout Madhya Pradesh. Folk medicinal specialists or traditional healer (Medicine men), assume an indispensable part in a medicinal services arrangement of both provincial and urban populace of the nation. It is vital to conduct broad meetings of individual medicine men of an area to get the overall status of medicinal plants. A survey was accomplished in the rustic territory of district Umaria, Madhya Pradesh. This investigation has uncovered a sum of 40 plants out of which 33 plants were identified, which belongs to 22 families. Whole plants and/or plant parts, like leaves, stems, barks, roots, flowers, fruits, seeds and wood were usually used by Biga tribe (Medicine men) for the treatment of different illnesses. Leaves (5%) were the most oftentimes used plant parts, trailed by roots (11%), fruits (3%) barks (5%), whole plants (3%), seeds (2%), latex (2%) and flowers (2%). Add up to 33 diverse individual illnesses professed to be restored by plant parts including Breast abscess, Cure carbuncle, Cure rheumatic, Cure scabies, Diabetes, Diarrhoea, Eczema, Haematuria, Headache, Jaundice, Leucorrhoea, Leukoderma, Menstrual disorder, Piles, Rat bites, Scorpion bite, Skin burns, Skin disease, Spermatorrhea, Stomachache, Toothache, Typhoid and fever, used to abortifacient, increase milk after delivery, Whooping cough and Wounds of animals. Several uses of the plants could be validated by available literature review. It is expected that other plants used for treatment of various diseases by the Biga tribes (medicine men) can be subjected for further bio-activity and phytochemical studies, which prompts disclosure of new medications.

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