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- 저자 : Mikkonen, S. (검색결과 2 건)
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Towards a Server-Centric Interaction Architecture for Wireless Applications
( Jussi Saarinen ),( Tommi Mikkonen ),( Sasu Tarkoma ),( Jani Heikkinen ),( Risto Pitkanen ) 한국인터넷정보학회 2008 KSII Transactions on Internet and Information Syst Vol.2 No.2
Traditional web-based services that require users to browse via documents and fill out forms, are difficult to use with mobile devices. Moreover, as the web paradigm assumes active clients, further complications are introduced in cases where the server is the active entity, instead of the client. This paper presents a Server-Centric Interaction Architecture (SCIA) for wireless applications. The architecture enables servers to initiate communication with clients as well as push secure targeted data to them, in a piecemeal fashion. It further enables the development of highly collaborative wireless services with interactive user interfaces.
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Makela, J.T.A.,Rezaeian, Z.S.,Mikkonen, S.,Madden, R.,Han, S.K.,Jurvelin, J.S.,Herzog, W.,Korhonen, R.K. Published for the Society by Baillère Tinda 2014 OSTEOARTHRITIS AND CARTILAGE Vol.22 No.6
Objective: The aim of this study was to investigate the site-dependent changes in the structure and function of articular cartilage in the lapine knee joint at a very early stage of osteoarthritis (OA), created experimentally by anterior cruciate ligament transection (ACLT). Methods: Unilateral ACLT was performed in eight mature New Zealand white rabbits. ACL transected and contralateral (C-L) joints were prepared for analysis at 4 weeks after ACLT. Three rabbits with intact joints were used as a control group (CNTRL). Femoral groove, medial and lateral femoral condyles, and tibial plateaus were harvested and used in the analysis. Biomechanical tests, microscopy and spectroscopy were used to determine the biomechanical properties, composition and structure of the samples. A linear mixed model was chosen for statistical comparisons between the groups. Results: As a result of ACLT, the equilibrium and dynamic moduli were decreased primarily in the femoral condyle cartilage. Up to three times lower moduli (P < 0.05) were observed in the ACLT group compared to the control group. Significant (P < 0.05) proteoglycan (PG) loss in the ACLT joint cartilage was observed up to a depth of 20-30% from the cartilage surface in femoral condyles, while significant PG loss was confined to more superficial regions in tibial plateaus and femoral groove. The collagen orientation angle was increased (P < 0.05) up to a cartilage depth of 60% by ACLT in the lateral femoral condyle, while smaller effects, but still significant, were observed at other locations. The collagen content was increased (P < 0.05) in the middle and deep zones of the ACLT group compared to the control group samples, especially in the lateral femoral condyle. Conclusion: Femoral condyle cartilage experienced the greatest structural and mechanical alterations in very early OA, as produced by ACLT. Degenerative alterations were observed especially in the superficial collagen fiber organization and PG content, while the collagen content was increased in the deep tissue of femoral condyle cartilage. The current findings provide novel information of the early stages of OA in different locations of the knee joint.
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