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Mehtap Demirel,Bunyamin Aksakal 한양대학교 세라믹연구소 2018 Journal of Ceramic Processing Research Vol.19 No.1
Hydroxyapatite (HA) based biografts were syntesized at 0.68, 1.2 and 2.4 μm powder particle size by sol gel method. The effectof powder particle sizes on morphology, mechanical properties and in vitro cell viability of the biografts were analysed. Eachcomposition at different particle sizes (0.68, 1.2 and 2.4 μm) were sintered at 1180 oC and quantitative phase analysis wascharacterized by FTIR, XRD and SEM-EDX. Mechanical properties were determined by axial compression and Vickershardness tests. The highest compresion strengths and hardness values were obtained in samples having the particle size of 0.68μm and such values were increased with decreased particle sizes. Furthermore, from in vitro Cell viability tests it wasdetermined that no toxicity was detected at 0,1 and 0,3 μM concentrations at lower powder particle sizes. However, cellviability was significantly reduced in the syntesized samples having 2.4 μm particle size at 0,3 μM concentration.