http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Prostate Cancer Cell-Specific Cytotoxicity of Sub-Micron Potassium Niobate Powder
Fisher, John G.,Thuan, Ung Trong,Farooq, Muhammad Umer,Chandrasekaran, Gopalakrishnan,Do Jung, Young,Hwang, Eu Chang,Lee, Je-Jung,Lakshmanan, Vinoth-Kumar American Scientific Publishers 2018 Journal of Nanoscience and Nanotechnology Vol.18 No.5
<P>Oxide nanoparticles have numerous potential applications in medicine such as carriers for therapeutic drugs, contrast agents for bio-imaging and targeting agents for tumors. Oxide nanoparticles may also have an inherent cytotoxicity towards cancer cells, as recently found for cerium oxide. KNbO3 nanoparticles have a combination of low toxicity and nonlinear optical properties which make them attractive for use as a bio-imaging material. However, little is known yet about the cytotoxicity of KNbO3 particles towards cancerous cells. In the present work, the cytotoxicity of KNbO3 particles to normal and prostate cancer cell lines is studied. The mixed oxide method is used to prepare KNbO3 powder. Using dynamic light scattering the mean particle diameter of the KNbO3 powder is found to be similar to 500 nm. X-ray diffraction, Fourier transform infra-red spectroscopy and Raman scattering spectroscopy are used to examine the structure of the KNbO3 powder. Powder morphology is examined using scanning electron microscopy. MTT assays of EA. hy926, PC-3 and DU-145 cell lines are carried out to study cell-specific cytotoxicity. KNbO3 sub-micron particles are found to have low toxicity to PC-3 cells, moderate toxicity to EA. hy926 cells and high toxicity to DU-145 cells. A new avenue towards the treatment of prostate cancer may be opened by the cell-specific cytotoxicity of KNbO3.</P>
Mining intelligent solution to compensate missing data context of medical IoT devices
Fisher, Paul S.,James II, Jimmy,Baek, Jinsuk,Kim, Cheonshik Springer-Verlag 2018 PERSONAL AND UBIQUITOUS COMPUTING Vol.22 No.1
<P>When gathering experimental data generated by medical IoT devices, the perennial problem is missing data due to recording instruments, errors introduced which cause data to be discarded, or the data is missed and lost. When faced with this problem, the researcher has several options: (1) insert what appears to be the best replacement for the missing element, (2) discard the entire instance, (3) use one of the algorithms that will consider the data and then suggest viable candidate values for replacement. We discuss the options and introduce another mining intelligent technique based upon Markov models.</P>
Fisher, John G.,Choi, Si-Young,Kang, Suk-Joong L. The Korean Ceramic Society 2011 한국세라믹학회지 Vol.48 No.6
The present study aims to identify the effect of sintering atmosphere [$O_2$, 75$N_2$-25 $H_2$ (mol%) and $H_2$] on microstructural evolution at the relatively low sintering temperature of 1040$^{\circ}C$. Samples sintered in $O_2$ showed a bimodal microstructure consisting of fine matrix grains and large abnormal grains. Sintering in 75 $N_2$ - 25 $H_2$ (mol %) and $H_2$ caused the extent of abnormal grain growth to increase. These changes in grain growth behaviour are explained by the effect of the change in step free energy with sintering atmosphere on the critical driving force necessary for rapid grain growth. The results show the possibility of fabricating $(K_{0.5}Na_{0.5})NbO_3$ at low temperature with various microstructures via proper control of sintering atmosphere.
Generation of Finite Inductive, Pseudo Random, Binary Sequences
Fisher, Paul,Aljohani, Nawaf,Baek, Jinsuk Korea Information Processing Society 2017 Journal of information processing systems Vol.13 No.6
This paper introduces a new type of determining factor for Pseudo Random Strings (PRS). This classification depends upon a mathematical property called Finite Induction (FI). FI is similar to a Markov Model in that it presents a model of the sequence under consideration and determines the generating rules for this sequence. If these rules obey certain criteria, then we call the sequence generating these rules FI a PRS. We also consider the relationship of these kinds of PRS's to Good/deBruijn graphs and Linear Feedback Shift Registers (LFSR). We show that binary sequences from these special graphs have the FI property. We also show how such FI PRS's can be generated without consideration of the Hamiltonian cycles of the Good/deBruijn graphs. The FI PRS's also have maximum Shannon entropy, while sequences from LFSR's do not, nor are such sequences FI random.
ON THE COMMUTATIVE PRODUCT OF DISTRIBUTIONS
Fisher Bring,Tas Kenan Korean Mathematical Society 2006 대한수학회지 Vol.43 No.2
The commutative products of the distributions $x^r\;ln^p\;{\mid}x{\mid}\;and\;x^{-r-1}ln^q\;{\mid}x{\mid}$ and of sgn x $x^r\;ln^p\;{\mid}x{\mid}\;and\;sgn\;x\;x^{-r-1}ln^q\;{\mid}x{\mid}$ are evaluated for $r=0,\;\pm1,\;\pm2,...\;and\;p,\;q=0,1,2,....$
Fisher, Benjamin A,Bang, So-Young,Chowdhury, Muslima,Lee, Hye-Soon,Kim, Jae-Hoon,Charles, Peter,Venables, Patrick,Bae, Sang-Cheol BMJ Publishing Group Ltd 2014 Annals of the Rheumatic Diseases Vol.73 No.4
<P><B>Objectives</B></P><P>Data from North European rheumatoid arthritis (RA) populations has suggested a particularly strong association of gene-environment interaction between smoking and HLA-DRB1 shared epitope (SE) with antibodies to citrullinated α-enolase (CEP-1) and vimentin (cVim) peptides. We investigated this further by examining anticitrullinated peptide/protein antibody (ACPA) fine specificity in a Korean cohort, where there are notable differences in the RA-associated HLA-DRB1 alleles.</P><P><B>Methods</B></P><P>Antibodies to fibrinogen (cFib), α-enolase (CEP-1) and vimentin (cVim) peptides and cyclic citrullinated peptide (CCP) were measured in 513 cases. The Mann-Whitney U test was used to compare antibody levels. Logistic regression generated ORs for RA in a case-control analysis with 1101 controls. Association of ACPA status and erosion in patients with RA was examined by logistic regression.</P><P><B>Results</B></P><P>Anti-CCP, CEP-1, cVim and fibrinogen peptides were found in 86.7%, 63.9%, 45.5% and 74.7%, respectively. The number of ACPA and their levels were associated with SE, with evidence of a gene-dosage effect. There was a particular association of smoking with levels of anti-CEP-1. However, a gene-environment interaction was associated with all the ACPA positive subgroups, albeit the highest OR was seen with the anti-CCP+/cVim+ subset. In the absence of SE, smoking only conferred risk for anti-CCP negative subsets. The presence of erosions was not associated with the number of positive ACPA or specificity.</P><P><B>Conclusions</B></P><P>The SE governed the magnitude and diversity of the ACPA response, but its interaction with smoking did not exclusively segregate with any of the ACPA specificities studied here. Smoking was associated with RA by SE-dependent and independent effects.</P>
SOME RESULTS ON THE COMMUTATIVE PRODUCT OF DISTRIBUTIONS
Fisher, Brian,Nicholas, Joel-D. Korean Mathematical Society 1999 대한수학회보 Vol.36 No.3
The commutative product of the distributions $x^r lnx and $x^{-r-1}$ is evaluated for r=0,1,2,.... The commutative product of the distributions $x^rln(x+i0) and $(x+i0)^{-r-1}$ is also evaluated for r=1,2,.... Further products are deduced.