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RISS 인기검색어
- 검색키워드
- 저자 : Cabrera-Fuentes, H. A. (검색결과 2 건)
- 무료
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- 유료
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Mortality and cancer after 12 versus 30 months dual antiplatelet therapy
Serebruany, V. L.,Kim, M. H.,Cabrera-Fuentes, H. A.,Lee, K.,Cho, Y. R.,Park, K.,Park, T. H.,Kim, Y. D.,Yoon, S.-C. F K SCHATTAUER VERLAGSGESELLSCHAFT MBH 2017 Thrombosis and haemostasis Vol.117 No.5
<P>The optimal duration and cancer risks of antiplatelet therapy following percutaneous coronary intervention (PCI) are unclear. We compared cancer and all-cause mortality after dual antiplatelet therapy (DAPT) for the combination of clopidogrel and aspirin (ASA) versus ASA alone over 18 months follow-up in event-free patients at 12 months DAPT from the Health Insurance Review and Assessment (HIRA) dataset via the Korean Outcomes Registry Evaluating Antithrombotics (KOREA). We selected PCI patients who were event free for 12 months and maintained a consistent antiplatelet regimen for 18 more months. The primary endpoints were any cancer and all-cause mortality at 30 months follow-up after PCI. From 320,351 screened post-PCI patient HIRA records, we excluded 294,413 and qualified 25,938, constituting DAPT (n=10,992) and ASA (n=14,946) groups. The Propensity Score Matching (PSM), and Inverse Probability of Treatment Weighting (IPTW) revealed no significant differences in back-ground demographics and clinical characteristics for DAPT versus ASA patients. At 30-months post-PCI, after massive (>91 %) exclusions, cancer risk was higher for continuous DAPT [455 (4.15 %) vs 606 (4.04 %); HR=1.221; 95 % CI: 1.061-1.405; p=0.005], which remained significant by PSM (p=0.006) or IPTW (p=0.007), while all-cause mortality was similar [136 (1.24 %) vs 192 (1.28 %) HR=0.999; 95 % CI: 0.736-1.135; p=0.993]. This analysis suggests a potential mild excess cancer risk, but no mortality benefit in Korean post-PCI patients treated with DAPT for an additional 18 months beyond conventional 12 months DAPT. These data are not supporting continuing DAPT for more than one year in East Asians. Analysing cancer types and assessing potential cancer association with bleeding are warranted.</P>
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Adhesion strength in laminated glazings containing multilayer solar control coatings
J. O. Aguilar,J. M. Rodríguez-Lelis,M. Carrasco de la Fuente,C. López-Mata,J. A. Arellano-Cabrera,F. Chan 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.6
We report on the mechanical and optical properties exhibited by a five layer laminated glazing (glass/PVB/PET/PVB/glass) in which a 0.1 mm thick polyethylene-terephthalate (PET) sheet carries a 70-110 nm CuS solar control coatings on either one or both sides of it and laminated with 0.38 mm clear polyvinyl-butyral (PVB) sheets in an autoclave at 135°C for 30 min under a pressure, 13 kg/cm2. The CuS coating was obtained by chemical deposition at 28°C during 1 h (70 nm) or 2 h (110 nm). The optical transmittance (T) of these laminated glazing is less than 1% in the ultraviolet region; 17-32% in the visible region, and 4-12% in the infrared region, depending on the CuS film thickness and whether the PET sheet is coated on one or both sides. The specular reflectance (R) of the glazing in the visible region is similar to that of a monolithic glass: about 10%, but in the infrared it increases toward 20%. The mechanical properties were evaluated through a compressive test giving interfacial adhesive strength of the laminated: 1.5-2 MPa for PET with a single side CuS coating and 3.4 MPa for the laminate with a PET coated on both sides.
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