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응웬하이박 외 중앙대학교 의과대학 의과학연구소 2011 中央醫大誌 Vol.36 No.3/4
We evaluate our experience with Transobturator Tape (TOT) surgery under local and general anesthesia for treating female stress incontinence. Totally 31 women with genuine urinary incontinent were selected in this study. They were scheduled for TOT surgery under local anesthesia or general anesthesia. The study protocol involved recording of preoperative and perioperative details and postoperative evaluation. Fifteen patients were included in local group and sixteen remainders in the general group. 100% of stress urinary incontinent symptom was cured. The cure rate of urge symptom was 80% vs. 50% for local group vs. general group, respectively, at both short-term and long-term follow-up. There was no significant difference in mean operating room and surgical time. But a statistically significant difference in mean of recovery room time, hospital stays and hospital cost was recorded (p <0.005). We concluded that TOT insertion is a best indication for correcting urinary stress incontinence in women. It can be performed effectively under both local and general anesthesia. Local anesthesia with sedation has advantage only in regarding to recovery time and total hospital cost, but much disadvantage in term of early and late postoperative complications.
Bac Xuan Nguyen,D. Mahinda Vilathgamuwa,Gilbert Foo,Peng Wang,Andrew Ong 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
LCL network is one of the best choices for compensating bidirectional inductive power transfer (BIPT) systems. However, H ? Bridge power converter of the conventional BIPT systems generates highly distorted AC current which results in reduced overall system efficiency particularly in high power BIPT systems. In order to overcome this drawback, a multilevel converter (MC) with selective harmonic distortion (SHE) modulation method is presented in this paper to eliminate high order harmonic components in converter voltages at both sides of BIPT systems. The proposed MC topology is constructed using a modified H ? Bridge converter with minimum number of power switches. The proposed topology is suitable for low to medium power applications. The simulation results demonstrate the feasibility of the proposed scheme.
Bac Tran Le,Jung-Eun Park 한국예방수의학회 2023 예방수의학회지 Vol.47 No.4
Previous studies have shown that proline mutations in the heptad repeat region stabilize the coronavirus spike (S) protein in a pre-fusion state. To understand the impact of proline substitutions on the fusogenicity of the S protein, we engineered the swine acute diarrhea syndrome coronavirus (SADS-CoV) S protein with two proline substitutions (S-PP) and examined its fusogenicity using dual-split-protein based cell-cell fusion assay. Unlike the wild-type S (S-WT), S-PP rarely formed syncytia. Additionally, protein expression of S-PP was impaired compared to S-WT, as previously reported. Our results indicate that pre-fusion stabilized S protein is unable to induce membrane fusion and provide a better understanding of SADS-CoV S and vaccine antigen design.
Preparation and Stability of Gold Colloid by Electrical Explosion of Wire in Various Media
Bac, L. H.,Yun, G. S.,Kim, J. S.,Choi, H. S.,Kim, J. C. American Scientific Publishers 2011 Journal of Nanoscience and Nanotechnology Vol.11 No.2
<P>Gold colloids were prepared by electrical explosion of wire in various media: cold water (0 degrees C), room temperature water (25 degrees C), hot water (80 degrees C), 0.01 M polysorbate surfactant 20 (TW 20) solution, mixture of 0.01 M TW 20 and 0.01 M ascorbic acid. The size distribution of nanoparticles measured by transmission electron microscope was found to shift to a smaller size with a decrease of temperature and a presence of TW 20 surfactant. The multiple light scattering results showed that medium temperature and ambient medium of explosion process is much influence on the stability of colloid. The gold colloid prepared in cold water is unstable in comparison with one prepared in warm and hot water. The best stability of gold colloid obtained with explosion medium of TW 20 and ascorbic acid solution.</P>