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- 저자 : Anupam Kaur (검색결과 3 건)
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Ratneev Kaur,Mandeep Kaur,Sukhjashanpreet Singh,Tajinder Kaur,Anupam Kaur 대한임상검사과학회 2022 대한임상검사과학회지(KJCLS) Vol.54 No.4
Polycystic ovary syndrome (PCOS) is a complex endocrinopathy in women of reproductive age. The genetics of PCOS is heterogeneous with the involvement of number of genes in the steroid synthesis pathway. The CYP11B2 encodes aldosterone synthase and the genetic variants might increase aldosterone secretion in PCOS cases. CYP1A1 is known to enhance the intraovarian catechol estrogen production and thus the propensity for PCOS. The present case-control study analyzed a total of 619 females for CYP11B2 (rs1799998) and CYP1A1 (rs4646903) polymorphisms. Obesity was examined according to body mass index (BMI) and waist hip ratio (WHR) categorization. Biochemical (lipid profile) analysis was performed in PCOS females. BMI (P=0.0001) and WHR (P=0.0001) revealed a statistically significant difference between PCOS cases and controls. The overall levels of triglycerides were higher in PCOS females. The genotype frequency distribution of CYP11B2 (rs1799998) polymorphism revealed statistically significant difference between PCOS cases and controls (P=0.017). However, CYP1A1 (rs4646903) polymorphism did not showed any association with PCOS. The present case-control association analysis is first from our region for CYP1A1 and CYP11B2 polymorphisms and is suggestive of genetic predisposition of steroidogenic genes among PCOS patients in the North-Indian Punjabi females.
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( Kirandeep Kaur ),( Amandeep Kaur ),( Anupam Kaur ) 대한임상검사과학회 2022 대한임상검사과학회지(KJCLS) Vol.54 No.1
Erythrocyte sedimentation rate (ESR) evaluation is a useful tool for monitoring disease activity in various inflammatory and non-inflammatory conditions. ESR is known to be influenced by a multitude of confounding factors. The present study aimed to assess the possible determinants of the ESR and its relationship with various risk factors involved in ischemic stroke. ESR and other hematological and biochemical parameters were investigated in 163 ischemic stroke patients (107 males and 56 females) selected based on imaging techniques including magnetic resonance imaging (MRI) or computed tomography (CT) scans. Statistical analysis was performed using the SPSS 16.0 software. Linear regression analysis showed a significant inverse relationship of hemoglobin (Hb) and hematocrit or packed cell volume (PCV) (P<0.001 for females; P<0.01 for males) with the ESR. It was observed that the red blood cell (RBC) count was not strongly correlated with the ESR (P<0.05 for both males and females). It was also observed that sex significantly affected the variables determining the ESR levels, whereas age had no effect. Gender differences were also observed with respect to Hb, RBC, PCV, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and ESR. The possible determinants of higher ESR levels in ischemic stroke may be sex, Hb, hematocrit, and RBC count, but the role of other clinical and laboratory parameters cannot be underestimated.
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Hierarchical Routing Techniques for Wireless Sensor Networks : A Comprehensive Survey
Ruchi Aggarwal,Anupam Mittal,Ramandeep Kaur 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.7
This paper describes the concept of routing in wireless sensor networks. Routing algorithm provides reliable path from source to destination. Energy efficiency is main constraint in Wireless Sensor Networks. For improving life time and energy consumption various routing algorithms have been proposed. In this paper describe the hierarchical routing techniques. Hierarchical routing includes tree based routing, cluster based routing, chain based protocol, and grid based routing. And also compare the hierarchical routing techniques.
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