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      • KCI등재

        혈청 전립선특이항원에 의한 전립선암 조기검진의 국가암검진사업 도입추진의 배경 및 타당성

        한준현(June Hyun Han),윤상진(Sang Jin Yoon),이영구(Young Goo Lee) 대한비뇨기종양학회 2010 대한비뇨기종양학회지 Vol.8 No.1

        Prostate cancer screening with prostate-specific antigen (PSA) has shown to reduce prostate cancer mortality by 20% in the European Randomized Study of Screening for Prostate Cancer (ERSPC) trial. Overdetection and overtreatment are substantial unfavourable side effects. However, the Prostate, Lung, Colorectal and Ovarian Cancer Screening (PLCO) trial did not show a significant reduction in prostate cancer mortality with screening. The results of PLCO was not acceptable because PSA contamination in the both screening and control cohort was found and the period of follow-up was not long enough to show the screening benefit to prostate cancer mortality. There are still controversies in PSA screening but the point of controversy has changed with time to issues of overdetection, overtreatment and a decrease in quality of life after treatment. Prostate cancer ranks as the fifth most common cancer among Korean men and the mortality rate of prostate cancer increases consistently. Recently, it is becoming a major public health concern in South Korea in relation to increased aging and westernization among Koreans. The Korean Government has implementing to National Cancer Screening Program since 1999, but the present status of male cancer control in South Korea leaves something to be desired. In order to improve mean mortality rate of major male cancers in Korean men, the introduction of prostate cancer screening to Korea national cancer screening program is needed.

      • KCI등재

        전립선비대증 환자의 수술적 치료에서 경요도 양극성 플라즈마 전립선기화술의 초기경험

        이용택(Yong Taec Lee),이동민(Dong Min Lee),류영우(Young Woo Ryu),임송원(Song Won Lim),염승희(Seung Hee Yum),한준현(June Hyun Han) 대한비뇨기종양학회 2011 대한비뇨기종양학회지 Vol.9 No.3

        Purpose: This study was conducted to introduce the initial experiences with transurethral bipolar plasma vaporization of the prostate (TBPVP) using ‘mushroom’ vapo-resection electrode for the treatment of benign prostatic hyperplasia (BPH) in Korean men. Materials and Methods: We retrospectively analysed the clinical data of 42 consecutive patients underwent TBPVP performed by a single surgeon between October 2009 and April 2011. The patients were assessed preoperatively and perioperatively, and were followed at 2, 4, and 8 weeks postoperatively. Patient baseline characteristics, perioperative data, postoperative outcomes, and major complications were recorded. Results: The mean age at surgery was 70.93±6.26 years. The mean prostate size was 64.10±17.83ml. The mean operation time was 59.40±25.99min, and the mean irrigation fluid volume during procedure was 26,000±10,511ml. The mean duration of catheterization was 3.57±0.94 days. The blood loss was minimal, and there was only 1 transfusion for the patient with ongoing heparization. Compared with baseline, there were significant improvements in IPSS, QoL, Qmax and postvoiding residual urine after surgery. Conclusions: The new TBPVP showed good short-term safety and efficacy for the treatment of Korean patients with BPH.

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