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조성재(Seongjae Jo) 한국진공학회 2021 진공 이야기 Vol.8 No.3
This paper explains biosensors based on localized surface plasmon resonance (LSPR). The biosensor that detect biological materials include a boundless range for selecting object, specifying a target, and detecting technology. Among the biosensors of various sensing techniques, this paper demonstrates the principles of LSPR and how this technology applies to sensors. To generating the LSPR effect, a nano-sized metal structure must be designed. Recently, a very precise LSPR sensor can be produced through advanced method of metal nanoparticle synthesis and metal nanostructure fabrication. The current research trends show several biological materials, such as DNA, RNA, antibodies, enzymes, proteins, cells, biological membranes and hormones, were detected through LSPR sensors with different nanoplasmonics methods, respectively. This above mechanism optimized by combining various LSPR methods can provide new insight into diverse techniques applied with nanoplasmonics. Furthermore, the research results have the potential to develop into a commercialized LSPR biosensor through these achievements.