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RISS 인기검색어
- 검색키워드
- 저자 : ( Wale Johnson Adeyemi ) (검색결과 3 건)
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Kazeem Bidemi Okesina,Adeyemi Fatai Odetayo,Wale Johnson Adeyemi,Ayodeji Johnson Ajibare,Akeem Ayodeji Okesina,Luqman Aribidesi Olayaki 한국실험동물학회 2024 Laboratory Animal Research Vol.40 No.1
Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder affecting many organs, including the testis. Naringin from orange peel extract (OPE) is a flavanone with fertility-enhancing properties. Hence, this study was designed to establish the effect of naringin on T2DM-induced testicular dysfunction. Thirty male (30) Wistar rats were randomized into five groups control, diabetes, diabetes + naringin, diabetes + OPE, and diabetes + metformin. The administrations were via the oral route and lasted for 28 days. Results: Naringin ameliorated T2DM-induced increase in FBS and decrease in serum insulin. It also abrogated T2DM-induced decrease in sperm quality, gonadotropin-releasing hormone, luteinizing hormone, follicle-stimulating hormone, testosterone, estradiol, prolactin, catalase, superoxide dismutase, and total antioxidant capacity. Furthermore, naringin prevented a T2DM-induced increase in malonaldehyde, tumor necrosis factor-alpha, C-reactive protein, xanthine oxidase (XO), and uric acid (UA), it was accompanied by the restoration of normal testicular histoarchitecture. Conclusions: Naringin prevented T2DM-induced testicular dysfunction by modulating XO/UA and restoring redox balance. Also, while the animals treated with OPE exhibited better ameliorative effects than their counterparts treated with naringin, the findings from this study showed that naringin would be a promising supplement for treating T2DM-induced male infertility. Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder affecting many organs, including the testis. Naringin from orange peel extract (OPE) is a flavanone with fertility-enhancing properties. Hence, this study was designed to establish the effect of naringin on T2DM-induced testicular dysfunction. Thirty male (30) Wistar rats were randomized into five groups control, diabetes, diabetes + naringin, diabetes + OPE, and diabetes + metformin. The administrations were via the oral route and lasted for 28 days. Results: Naringin ameliorated T2DM-induced increase in FBS and decrease in serum insulin. It also abrogated T2DM-induced decrease in sperm quality, gonadotropin-releasing hormone, luteinizing hormone, follicle-stimulating hormone, testosterone, estradiol, prolactin, catalase, superoxide dismutase, and total antioxidant capacity. Furthermore, naringin prevented a T2DM-induced increase in malonaldehyde, tumor necrosis factor-alpha, C-reactive protein, xanthine oxidase (XO), and uric acid (UA), it was accompanied by the restoration of normal testicular histoarchitecture. Conclusions: Naringin prevented T2DM-induced testicular dysfunction by modulating XO/UA and restoring redox balance. Also, while the animals treated with OPE exhibited better ameliorative effects than their counterparts treated with naringin, the findings from this study showed that naringin would be a promising supplement for treating T2DM-induced male infertility.
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Israel Arogundade Ojo,Olufunmilola Leah Dominic,Wale Johnson Adeyemi 대한물리의학회 2022 대한물리의학회지 Vol.17 No.2
PURPOSE: The functional limitations in stroke survivors promote sedentary lifestyles and quality of life inadequacies, but there is increasing evidence that this could be minimized by physical exercise. Therefore, this study examined the effects of physical exercise on the quality of life (QoL) and functional capacity (ability to stand up from a sitting position) among stroke survivors drafted from two tertiary hospitals in Osogbo, Nigeria. METHODS: A purposive sampling technique was used to select 21 registered right or left outpatient hemiplegic stroke survivors in a pre- and post-test experimental research design. The research questions were presented using descriptive statistics of frequency, percentage, mean and standard deviation, while an Analysis of Variance (ANOVA) was used to test the study hypothesis at the .05 alpha level for significance. RESULTS: Compared to the baseline (week 0), there were significant increases in the general quality of life, healthy well-being, physical exercise, pain perception, and environmental domains of QOL among the survivors in week four. Moreover, a significant increase was observed in these indices in week eight, compared to week four, except for the pain perception domain. Compared to the baseline, there was a significant decrease in the time it took the stroke survivors to stand up from a sitting position in week four. A significant decrease was observed in this index in week eight compared to week four. CONCLUSION: Marked corridor 20 meters brief walking exercise for eight weeks significantly improved the quality of life and ability to stand up from a sitting position in stroke survivors in Osogbo, Nigeria.
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( Israel Arogundade Ojo ),( Olufunmilola Leah Dominic ),( Wale Johnson Adeyemi ) 대한물리의학회 2021 대한물리의학회지 Vol.16 No.2
PURPOSE: This study examined the effects of an eight weeks twenty meters walk on the cardiorespiratory fitness and strength of the shoulder extensor, hip extensor, and dorsiflexor of stroke survivor outpatients in two tertiary hospitals in Osogbo, Nigeria. METHODS: A purposive sampling technique was used to select 21 registered right or left outpatient hemiplegic stroke survivors in a pre- and post-test experimental research design. The research questions were presented using the descriptive statistics of frequency, percentage, mean, and standard deviation. The differences between the mean of the cardio-respiratory indices and the muscle strength were tested by repeated measures analysis of variance followed by Bonferroni post-hoc test for multiple comparisons. RESULTS: No significant differences in heart rate were observed at week 0 compared to week 4. A significant decrease was recorded in the parameter at week 8, compared to week 4. Moreover, there were significant decreases in blood pressure and respiratory rate in week 0, compared to week 4, and in the respiratory rate, compared to week 8. In contrast, significant elevations in VO2 max were observed in week 0, compared to week 4, and in the week 4, compared to week 8. Furthermore, significant elevations in muscular strength were documented when comparisons were made at weeks 0, 4, and 8. CONCLUSION: Eight weeks of twenty meters walk aerobic exercise improve the cardio-respiratory fitness and muscular strength of stroke survivor outpatients.
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