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      • KCI등재

        ANALYTICAL DESCRIPTION OF RIDE COMFORT AND OPTIMAL DAMPING OF CUSHION-SUSPENSION FOR WHEEL-DRIVE ELECTRIC VEHICLES

        Fuxing Yang,Leilei Zhao,Yuewei Yu,Changcheng Zhou 한국자동차공학회 2017 International journal of automotive technology Vol.18 No.6

        To provide initial design values of seat cushion and chassis suspension damping for wheel-drive electric vehicles (WDEVs), this paper presents an analytical estimation method and a practical damping parameters design method. Firstly, two formulae of the human body vertical acceleration in terms of the power spectrum density (PSD) and the root mean square (RMS) are deduced for WDEVs. Then, the coupling effects of the key vehicle parameters on ride comfort are revealed. Finally, with a practical example, the damping parameters of the cushion and the suspension are initially designed and analyzed. The results show that when every 10.0 kg increases for motor mass, the optimal damping values of the cushion and the suspension should be reduced by about 15.0 Ns/m and 50.0 Ns/m, respectively. However, the RMS acceleration increases 0.017 m/s2 with a decrease of 2.5 % for ride comfort.

      • SCIESCOPUSKCI등재

        Evaluating Pharmacological Effects of Two Major Components of Shuangdan Oral Liquid: Role of Danshensu and Paeonol in Diabetic Nephropathy Rat

        Chen, Ying,Liu, Zhuying,Zhou, Fuxing,Zhao, Hang,Yang, Qian,Li, Hua,Sun, Jiyuan,Wang, Siwang The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.5

        Shuangdan oral liquid (SDO) containing radix Salviae miltiorrhizae (Chinese name Danshen) and cortex moutan (Chinese name Mudanpi) is a traditional Chinese medicine using for treating vascular diseases. Danshensu (DSS) is a main effective monomer composition derived from radix Salviae miltiorrhizae and paeonol (Pae) from cortex moutan. Although the two herbs are widely used in traditional Chinese medicine, the pharmacological functions of their active compositions were not reported. Therefore, the research of DSS and Pae in mechanisms and pharmacodynamics interaction can provide scientific evidence to support clinical application. The diabetic nephropathy (DN) rats which were induced by streptozotocin (STZ) were treated with SDO, DSS, Pae, and DSS+Pae for eight weeks. The positive effects on DN animal models were investigated by detection of physiological and biochemical indexes and oxidative stress markers, within five treatments: SDO, DSS, Pae, DSS+Pae and insulin group. Compared with the model group, the DSS+Pae group improved the renal function, blood lipid metabolism and blood viscosity, increased the vitality of T-SOD or T-AOC and decreased the level of MDA or NO after the treatment. The study was successfully showed that the DSS+Pae group could delay the process of DN, especially in the renal injury part of histopathology changes. Our results suggest that the co-administration of DSS and Pae significantly may play a protective role in DN rats through decreasing the oxidative stress and improving the blood lipid metabolism mechanisms.

      • KCI등재

        A method for evaluating the stiffness of a cabin suspension system for fork lift trucks

        Leilei Zhao,Changcheng Zhou,Yuewei Yu,Fuxing Yang 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.10

        The stiffness parameters of cabin suspension have an important effect on the comfort of fork lift trucks. Analysis of the cabin system of fork lift trucks often requires the retrieval of the stiffness parameters of cabin suspension systems. Convenient methods of retrieving stiffness parameters without dismantling the cabin suspension system cannot be obtained unless a special bench test is conducted. This process is inconvenient for researchers and technicians. A cabin model with three degrees of freedom was constructed, including a simulation model, to provide a convenient method for retrieving stiffness parameters. A model for the identification of stiffness parameters was established on the basis of the test data and the simulation model. The stiffness parameters were identified through a case study and the values retrieved coincide with the test results. The results show that the method built is reliable and provides an effective way of retrieving the stiffness parameters of cabin suspension for fork lift trucks.

      • KCI등재

        Evaluating Pharmacological Effects of Two Major Components of Shuangdan Oral Liquid: Role of Danshensu and Paeonol in Diabetic Nephropathy Rat

        ( Ying Chen ),( Zhuying Liu ),( Fuxing Zhou ),( Hang Zhao ),( Qian Yang ),( Hua Li ),( Jiyuan Sun ),( Siwang Wang ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.5

        Shuangdan oral liquid (SDO) containing radix Salviae miltiorrhizae (Chinese name Danshen) and cortex moutan (Chinese name Mudanpi) is a traditional Chinese medicine using for treating vascular diseases. Danshensu (DSS) is a main effective monomer composition derived from radix Salviae miltiorrhizae and paeonol (Pae) from cortex moutan. Although the two herbs are widely used in traditional Chinese medicine, the pharmacological functions of their active compositions were not reported. Therefore, the research of DSS and Pae in mechanisms and pharmacodynamics interaction can provide scientific evidence to support clinical application. The diabetic nephropathy (DN) rats which were induced by streptozotocin (STZ) were treated with SDO, DSS, Pae, and DSS+Pae for eight weeks. The positive effects on DN animal models were investigated by detection of physiological and biochemical indexes and oxidative stress markers, within five treatments: SDO, DSS, Pae, DSS+Pae and insulin group. Compared with the model group, the DSS+Pae group improved the renal function, blood lipid metabolism and blood viscosity, increased the vitality of T-SOD or T-AOC and decreased the level of MDA or NO after the treatment. The study was successfully showed that the DSS+Pae group could delay the process of DN, especially in the renal injury part of histopathology changes. Our results suggest that the co-administration of DSS and Pae significantly may play a protective role in DN rats through decreasing the oxidative stress and improving the blood lipid metabolism mechanisms.

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