Treatment of severe erythematotelangiectatic rosacea with intense pulsed light: a case report

Cheuk Hung Lee(Cheuk Hung Lee),Kar Wai Alvin Lee(Kar Wai Alvin Lee ),Kwin Wah Chan(Kwin Wah Chan ) 대한미용의학회 2023 대한미용의학회지 Vol.7 No.1

Erythematotelangiectatic rosacea is a common, long-standing inflammatory skin disorder of unclear origin. It is characterized by facial erythema involving mainly the central face (malar areas, chin, nasal area, and forehead region), with a range of clinical manifestations varying from blood vessels hyperactivity to sebaceous glands hyperplasia. These can have a considerable psychosocial impact on the patients. Intense pulsed light treatment can have significant effects on severe erythematotelangiectatic rosacea. We aimed to describe the treatment of severe erythematotelangiectatic rosacea with intense pulsed light. This article is a case report together with a literature review to explore the views of researchers on the treatment of erythematotelangiectatic rosacea with intense pulsed light. Pre-treatment and post-treatment clinical photographs are provided to show the effects of intense pulsed light therapy on severe erythematotelangiectatic rosacea. No comparisons were made with the other treatment modalities; nevertheless, this study provides an alternative treatment option for patients with severe erythematotelangiectatic rosacea. Our case report revealed that intense pulsed light using multiple filters at certain energy levels can effectively treat severe erythematotelangiectatic rosacea. We believe that, with more treatment sessions, patients can enjoy longer and more persistent results. Intense pulsed light is an effective treatment for erythematotelangiectatic rosacea. However, more erythematotelangiectatic rosacea cases treated with intense pulsed light will be required to consolidate intense pulsed light as one of the best treatment options for erythematotelangiectatic rosacea. Potential complications with intense pulsed light include post-inflammatory hyperpigmentation, burns, and pain.

Treatment of acne fulminans with intense pulsed light: a case report

Cheuk Hung Lee(Cheuk Hung Lee),Kar Wai Alvin Lee(Kar Wai Alvin Lee),Kwin Wah Chan(Kwin Wah Chan),Kar Wai Phoebe Lam(Kar Wai Phoebe Lam ) 대한미용의학회 2022 대한미용의학회지 Vol.6 No.2

Acne fulminans is a severe form of acne that has a considerable psychosocial impact. Acne scarring is a potential complication of this condition. The treatment of acne fulminans includes conventional topical antibiotics, systemic antibiotics, hormonal therapy, isotretinoin, and light therapy. Intense pulsed light can have marked effects on acne fulminans. We aimed to describe the treatment of acne fulminans with intense pulsed light. This article is a case report together with a literature review to demonstrate how intense pulsed light can be used to treat acne fulminans. Pre-treatment and post-treatment clinical photographs are provided to show the effects of intense pulsed light therapy on acne fulminans. No comparisons were made with the other treatment modalities; nevertheless, this study provides an alternative treatment option for acne fulminans. Our case report revealed that intense pulse light using multiple filters at certain energy levels can effectively treat acne fulminans. Current evidence suggests that ablative CO2 and Er:YAG lasers provide the best curative effect on acne scars on all skin types. Potential complications with intense pulsed light include pain, burns, and post-inflammatory hyperpigmentation. Intense pulsed light is an effective treatment modality for acne fulminans. However, more cases of acne fulminans treated with intense pulsed light need to be documented in order to affirm intense pulsed light as one of the best options for treating this severe form of acne.

P107 : The effect of D-panthenol containing physiologic lipid mixture in multi-lamellar emulsion on intense pulsed light treated facial skin: a split-face, evaluator-blinded, randomized pilot study

( Dae Suk Kim ),( Dongyun Shin ),( Howard Chu ),( Se Kyoo Jeong ),( Min Geol Lee ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Background: Intense pulsed light (IPL) is widely performed light-based treatment for various indications. However, post-IPL treatment methods have not been studied widely. Objectives: To investigate the effect of novel topical physiologic lipid mixture agent, which contains D-panthenol in multi-lamellar emulsion, after IPL treatment. Methods: Fifteen subjects were randomly assigned to apply study cream on one side of their face and control cream on the other side for 4 weeks after IPL treatment. Assessments included clinical photographs, clinical grading by a physician, subjects’ self-assessments and objective measurements of skin color, hydration and trans-epidermal water loss (TEWL). Results: Subjects were more satisfied with study cream compared to control cream (P<0.05). Study cream significantly accelerated the recovery of epidermal permeability barrier function compared to control cream, when measured by TEWameter (P<0.05). Other assessments did not show statistical difference between study cream and control cream treated sides. The results demonstrate that study cream may provide better improvements compared to control cream after IPL treatment. Conclusion: Though study cream was not superior to control cream in all aspects, we think D-panthenol containing physiologic lipid mixture with multi-lamellar emulsion agent can be used as a safe and effective agent to improve outcomes after IPL treatment.

Topical Aminolaevulinic Acid-Photodynamic Therapy for the Treatment of Mild to Moderate Inflammatory Acne

( June Hyun Kyung Lee ),( Seong Eon Kim ),( Kun Park ),( Sook Ja Son ) 대한피부과학회 2007 Annals of Dermatology Vol.19 No.2

Background: Photodynamic therapy (PDT) using aminolevulinic acid (ALA) is a new technique. PDT is being studied extensively and is used in a variety of dermatology settings. Objective: The purpose of this study was to evaluate the safety and efficacy of topical ALA-PDT in patients with mild to moderate inflammatory acne. Method: Ten patients were enrolled in a clinical trial to evaluate ALA-PDT with activation by intense pulsed light. They were given a 20% topical ALA photosensitizing agent that remained in contact with the skin for 60 minutes before irradiation. No additional treatment was provided after PDT. Results: The Korean acne grading system was used for clinical assessment. Our results showed a statistically significant clinical improvement of the inflammatory acne at eight weeks after two sessions of treatment. Side effects such as slight discomfort, burning and stinging were reported during the irradiation. Conclusion: ALA-PDT is a safe and effective treatment modality for inflammatory acne. (Ann Dermatol (Seoul) 19(2) 55~59, 2007)

Intense Pulsed Light and Q-Switched 1,064-nm Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment for the Scarring Lesion of Discoid Lupus Erythematosus

( Yun Sun Byun ),( Jee Hee Son ),( Yong Se Cho ),( Bo Young Chung ),( Hee Jin Cho ),( Chun Wook Park ),( Hye One Kim ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.3

Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus that can cause permanent scarring. Treatment of DLE includes protection from sunlight and artificial sources of ultraviolet light, as well as systemic and topical medications. The first-line standard therapies are antimalarials and topical steroids. Other systemic therapies include systemic steroid, azathioprine, dapsone, and immunosuppressive agents. Topical tacrolimus and pimecrolimus have also been evaluated. Recent studies reported that several treatments, including pulsed dye laser, CO2 laser, intense pulsed light (IPL), and 1,064-nm long-pulse neodymium- doped yttrium aluminum (Nd:YAG) have been used for the cosmetic treatment of DLE. Here, we report a case of a DLE scar that was successfully treated with a combination therapy of IPL and Q-switched 1,064-nm Nd:YAG laser. (Ann Dermatol 29(3) 331∼333, 2017)

Case report: treating vitiligo with intense pulsed light

Cheuk Hung Lee(Cheuk Hung Lee),Kar Wai Alvin Lee(Kar Wai Alvin Lee ),Kwin Wah Chan(Kwin Wah Chan ) 대한미용의학회 2023 대한미용의학회지 Vol.7 No.1

Erythematotelangiectatic rosacea is a common, longstanding inflammatory skin disorder with unclear origin. It is characterized by facial erythema involving mainly the central face (malar areas, the chin, nasal area and forehead region) with a range of clinical presentations varying from hyperactivity of the blood vessels to sebaceous gland hyperplasia. It can lead to considerable psychosocial impact. Intense pulsed light (IPL) treatment can potentially have dramatic results on severe erythematotelangiectatic Rosacea. This is a case report of treating severe erythematotelangiectatic rosacea with IPL treatment. Pre-treatment and post-treatment clinical photos were provided to show the effect of IPL therapy on severe erythematotelangiectatic rosacea. This article is a case report together with literature review to explore the view of researchers on erythematotelangiectatic rosacea with IPL. No comparison is made with other treatment modalities. Nevertheless, it provides an alternative treatment option for patients with severe erythematotelangiectatic rosacea. Our case report shows that IPL at certain energy levels using multiple filters, can effectively treat severe erythematotelangiectatic rosacea. We believe with more treatment sessions patient can enjoy longer and persistent result. IPL is an effective treatment for erythematotelangiectatic rosacea. However, more erythematotelangiectatic rosacea cases treating with IPL will be required to consolidate IPL as one of the best treatment options in treating erythematotelangiectatic rosacea. Potential complications with IPL include post-inflammatory hyperpigmentation, burn and pain.

Intense pulsed light as an alternative treatment for erythematotelangiectatic rosacea: a case report

Jiwon Lee,Sang Ju Lee,Han Kyoung Cho 대한의학레이저학회 2024 MEDICAL LASERS Vol.13 No.1

Rosacea is a chronic inflammatory condition characterized by recurrent episodes of flushing, persistent erythema, inflammatory papules, pustules, and telangiectasia that usually affects the centrofacial region. Conventional oral and topical agents primarily target inflammatory papules and pustules, but limited evidence supports their ability to manage background facial erythema and telangiectasia. Instead, recommendations favor intense pulsed light (IPL) or vascular lasers, such as the pulsed dye laser (PDL), for treating erythematotelangiectatic rosacea (ETR). Previous studies have confirmed the effectiveness of PDL and IPL as treatments for facial erythema and telangiectasia. This report details the case of a 66-year-old Korean female with ETR successfully treated with IPL and highlights its potential as an alternative treatment option for ETR patients refractory to PDL and conventional medications.

Intense Pulsed Light Alone and in Combination with Erbium Yttrium-Aluminum-Garnet Laser on Small-to-Medium Sized Congenital Melanocytic Nevi: Single Center Experience Based on Retrospective Chart Review

( Mi So Lee ),( Hee Jin Jun ),( Sang Hyun Cho ),( Jeong Deuk Lee ),( Hei Sung Kim ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.1

Background: Treatment of congenital melanocytic nevi (CMN) with intense pulsed light (IPL) has recently produced promising results. Objective: To evaluate the clinical and histological outcomes of small-to-medium sized CMN treated with IPL alone and in combination with erbium: yttrium-aluminum- garnet (Er: YAG) laser. Methods: We performed a retrospective chart review of 26 small-to-medium sized CMN treated as described above. The reduction in visible pigmentation, signs of recurrence and any adverse skin changes were evaluated by two independent clinicians. Results: Seventeen patients completed treatment and were followedup. Nine were not able to complete treatment due to work, change in residence, and treatment related stress. Ten patients received IPL alone (mean: 10.5 sessions) and 7 underwent treatment with IPL (mean: 7.7 sessions) and Er: YAG/IPL combination therapy (mean: 4.7 sessions). The initial treatment outcome was cleared in 5 patients and excellent in 12. Fourteen patients (82.4%) showed CMN recurrence one year after treatment completion. The histological results from a patient with an excellent clinical outcome showed remnant nevus cells nests in the deep dermis. Conclusion: IPL treatment alone and in combination with Er: YAG laser are not definitive treatments for CMN and should not be considered as first-line treatment. (Ann Dermatol 29(1) 39∼47, 2017)

The Efficacy of Intense Pulsed Light for Treating Erythematotelangiectatic Rosacea Is Related to Severity and Age

( Hee Sun Lim ),( Seung Chul Lee ),( Young Ho Won ),( Jee Bum Lee ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.4

Background: Rosacea is a chronic cutaneous disease. Therapeutic modalities should be chosen based on the identified sub-types and clinical features in each patient. Vascular lasers, including intense pulsed light (IPL), are reportedly safe and effective in treating erythematotelan-giectatic rosacea (ETR). Objective: In this study, we assess the comparative efficacy of IPL related to several factors including clinical severity and the age of patients with ETR. Methods: Patients with ETR were classified into two groups according to the National Rosacea Society Severity Guideline. Severity score and erythema index (EI) were measured using a clinical scorecard and mexameter. For additional evaluation of therapeutic efficacy, investigator and patient global assessments (IGA, PGA) were checked. Efficacy of IPL was analyzed according to severity score, EI, IGA, and PGA related to sex, age, lactic acid stinging test, and severity. Results: Analyses of the efficacy of IPL according to severity score, EI, IGA, and PGA based on sex, age, lactic acid stinging test, and severity revealed significant differences with age and severity only. Conclusion: This study supports the efficacy of IPL treatment for patients with ETR. IPL may be more effective in patients with more severe ETR and in younger patients with ETR. (Ann Dermatol 26(4) 491~495, 2014)

1,213 cases of treatment of facial acne using indocyanin green and intense pulsed light in Asian skin

( Joon Hyuk Suh ),( Moo Yeol Hyun ),( Kui Young Park ),( Myeung Nam Kim ),( Chang Kwun Hong ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

Background: Photodynamic therapy (PDT) has been used for acne, with various combinations of photosensitizers and light sources. Objectives: We aimed to evaluate the effectiveness and safety of indocyanin green (ICG) and intense pulsed light (IPL) in the treatment of acne. Methods: A total of 1,213 patients with facial acne were retrospectively reviewed. Patients received three or five treatments of ICG and IPL at two-week intervals. Clinical response to treatment was assessed by comparing pre- and post-treatment clinical photographs and patient satisfaction scores. Results: A total of 1,213 patients with facial acne were retrospectively reviewed. Patients received three or fivetreatments of ICG and IPL at two-week intervals. Clinical response to treatment was assessed by comparing pre- and post-treatment clinical photographs and patient satisfaction scores. Conclusion: These results suggest that PDT with ICG and IPL can be effectively and safely used in the treatment of acne.