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Vietla S. Rao,Celio L. de Melo,Maria Goretti R. Queiroz,Telma L.G. Lemos,Dalgimar B. Menezes,Tiago S. Melo,Flavia A. Santos 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.11
Currently, there is renewed interest in plant-based medicines and functional foods for the prevention and cure of obesity and its associated risk of cardiovascular disease and metabolic syndrome. In the search for potential anti-obesity compounds from natural sources, the effects of ursolic acid (UA), a pentacyclic triterpenoid widely found in medicinal herbs and fruits, was evaluated for its effects on blood glucose, lipids, and abdominal fat deposition in mice fed a high-fat diet (HFD). Adult male Swiss mice treated or not with UA (0.05%, 50 mg/L, in drinking water) were fed HFD for 15 weeks. A sibutramine (SIB)-treated group (0.05% in drinking water) was included as the positive control. Weekly body weights and food and water consumption were measured, and at the end of the study period, the levels of blood glucose and lipids, the plasma hormones insulin, ghrelin, and leptin, and the abdominal fat accumulation were analyzed. Mice treated with UA and fed HFD showed significantly (P<.05) decreased body weights, visceral adiposity, and levels of blood glucose and plasma lipids relative to their respective controls not fed UA. Also, a significant increase was observed in plasma leptin with a decrease in ghrelin, as well as of amylase and lipase activities. The SIB-treated group also manifested effects similar to those of UA except for the blood glucose level, which was not different from the HFD control. These findings suggest that UA ameliorates abdominal adiposity and decreases the levels of blood glucose and plasma lipids in mice and thus manifests an anti-obesity potential through absorptive and metabolic targets.
de Andrade Robson C.,Menezes Rodrigo S. Gonzaga,Fiuza-Jr Raildo A.,Andrade Heloysa Martins Carvalho 한국탄소학회 2021 Carbon Letters Vol.31 No.4
Mango fruit seed shells were used as starting materials to produce activated carbons for the capture of acetone, a typical volatile organic compound (VOC), from gaseous streams. This fruit waste presents high volatiles and low ashes contents, as expected for the lignocelulosic materials commonly used for the preparation of activated carbons. The starting material was hydrothermally treated at 180 or 250 °C for 5 h and the obtained hydrochars were activated with KOH solutions. The carbon samples were characterized by SEM, EDX, TG/DTA, Raman spectroscopy and textural analysis by physisorption. The adsorption capacity and adsorption cycles were investigated by TG. The hydrochars presented spherical morphology and the activated carbons derived from them presented heterogeneous micropore structures allowing to high capacity of acetone vapor removal, namely 472 mg/g, at 30 °C and 363 mg/g, at 50 °C. The results indicate that the adsorption capacity of the activated carbons is directly related to their Dubinin-Astakhov micropore surface areas and microporous volumes determined by NLDFT. The adsorption of acetone vapor showed a pseudo-frst order kinetics and both external and intraparticle transport contributed for the overall process. Highly efcient and stable acetone vapor removal was observed over the activated carbons after fve cycles.
Rodrigues, E.C.,Sharma, S.K.,de Menezes, A.S.,Chae, K.H.,Gautam, S.,Aljawf, R.N.,Kumar, S. Pergamon Press 2016 Materials research bulletin Vol.83 No.-
Thin film of Ti<SUB>0.95</SUB>Co<SUB>0.05</SUB>O<SUB>2-δ</SUB> was deposited on Si (100) using PLD method and annealed in O<SUB>2</SUB> and N<SUB>2</SUB> environment. Raman spectra confirm that all the films have rutile structure. Surface morphology indicates that the surface roughness and grain size increase with annealing. The electronic structure studied by NEXAFS spectroscopy at O K, Ti L<SUB>3,2</SUB> and Co L<SUB>3,2</SUB>-edges revealed that peak intensities decrease significantly for the film annealed N<SUB>2</SUB> environment. The ligand-field splitting estimated from the energy difference between the t<SUB>2g</SUB> and e<SUB>g</SUB> features in O K-edge spectra were 2.71eV for as-deposited and O<SUB>2</SUB> annealed film, whereas reduced more than double (@?1.32eV) for the film annealed in N<SUB>2</SUB>. Atomic multiplet calculations and experimentally observed NEXAFS spectra at Co L<SUB>3,2</SUB>-edge and Ti L<SUB>3,2</SUB>-edge confirm that Co present in 2+ and Ti in +4 valence state, whereas the multiplet structures of O<SUB>2</SUB> annealed film looks similar to Co metal.