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RISS 인기검색어
- 검색키워드
- 저자 : Zimmerman Zachary (검색결과 3 건)
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Migraine-Associated Otalgia: An Underappreciated Entity
Sussman Sarah,Zimmerman Zachary,Chishom Taylor,Reid Lauren,Seyyedi Mohammad 대한청각학회 2022 Journal of Audiology & Otology Vol.26 No.2
Background and Objectives: Otalgia can be primary/otogenic or secondary as a referred pain from another site, which can be difficult to establish owing to various causes and the complex innervation of the ear. In our center, we observed a large group of patients with unexplained otalgia that had a higher prevalence of migraine. We hypothesized that migraine may cause secondary otalgia. This study then aimed to determine the prevalence of migraine-associated otalgia and evaluate the efficacy of migraine treatment.Subjects and Methods: This 2-year retrospective study was conducted at a busy otology clinic. Patients were identified using diagnostic codes corresponding to otalgia. The prevalence of migraine-associated otalgia was determined, and the efficacy of migraine treatment was evaluated in these patients. The interventions included prophylactic and abortive migraine treatments. Statistical analysis was conducted to compare between the pre- and post-treatment symptoms.Results: A total of 208 patients with otalgia were identified. Sixty-four out of ninety patients with unexplained otalgia met the criteria for migraine; of them, 30 patients had an adequate follow-up and were thus included in the evaluation of treatment efficacy. Otalgia improved in 87% of the patients who received migraine treatment. After treatment, the mean pain score and headache frequency significantly decreased from 7 to 2 and from 27 to 9 days per month, respectively (p<0.001).Conclusions: Migraine should be considered as a source of secondary otalgia, and patients should receive treatment as they often respond to migraine treatment.
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Venkatkrish Manohar Kasetty,Zachary Zimmerman,Sarah King,Mohammad Seyyedi 대한청각학회 2019 Journal of Audiology & Otology Vol.23 No.4
Background and Objectives: Facial nerve stimulation (FNS) is a complication of cochlear implantation (CI). This study compared the thickness and density of the bone separating the upper basal turn of the cochlea (UBTC) and the labyrinthine segment of the facial nerve (LSFN) on preoperative computed tomography (CT) in patients with and without FNS after CI. Subjects and Methods: Adult patients who underwent CI from January 2011 to February 2017 with preoperative CT at a tertiary referral hospital were considered for this retrospective case– control study. Patients were divided into two groups: with FNS (n=4) and without FNS (n=53). The density and thickness of the bone between the LSFN and UBTC were measured on preoperative CT. Charts were reviewed for other parameters. Results: A statistically significant difference was seen in the thickness (p=0.007) but not in the density (p=0.125) of the bone between the UBTC and LSFN. Four patients had FNS at the mid-range electrode arrays, and one of them additionally had FNS at the basal arrays. Conclusions: Decreased thickness of the bone between the UBTC and LSFN can explain postoperative FNS, confirming the histologic and radiologic findings in previous studies, which indicated that the thickness of the temporal bone between the LSFN and UBTC is less in patients who experience FNS. While the density in this region was also less, it was not statistically significant.
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Nano-structural effects on Hematite (α-Fe2O3) nanoparticle radiofrequency heating
Powell Camilah D.,Lounsbury Amanda W.,Fishman Zachary S.,Coonrod Christian L.,Gallagher Miranda J.,Villagran Dino,Zimmerman Julie B.,Pfefferle Lisa D.,Wong Michael S. 나노기술연구협의회 2021 Nano Convergence Vol.8 No.8
Nano-sized hematite (α-Fe 2 O 3 ) is not well suited for magnetic heating via an alternating magnetic field (AMF) because it is not superparamagnetic—at its best, it is weakly ferromagnetic. However, manipulating the magnetic properties of nano-sized hematite (i.e., magnetic saturation (Ms), magnetic remanence (Mr), and coercivity (Hc)) can make them useful for nanomedicine (i.e., magnetic hyperthermia) and nanoelectronics (i.e., data storage). Herein we study the effects of size, shape, and crystallinity on hematite nanoparticles to experimentally determine the most crucial variable leading to enhancing the radio frequency (RF) heating properties. We present the synthesis, characterization, and magnetic behavior to determine the structure–property relationship between hematite nano-magnetism and RF heating. Increasing particle shape anisotropy had the largest effect on the specific adsorption rate (SAR) producing SAR values more than 6 × greater than the nanospheres (i.e., 45.6 ± 3 W/g of α-Fe 2 O 3 nanorods vs. 6.89 W/g of α-Fe 2 O 3 nanospheres), indicating α-Fe 2 O 3 nanorods can be useful for magnetic hyperthermia.
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