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- 저자 : Zhenni Zhang (검색결과 2 건)
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Functional Evaluation of Bovine Collagen and Cistanche Deserticola Compound Peptide
Chunyu Guo,Zhenni Zhang,Yan Zhang,Bo Yang,Xia Wue East Asian Health Association 2024 Journal of East Asian Bealth Vol.1 No.1
Purpose – Considering that elderly men’s health has common problems among the elderly. For example, most elderly chronic diseases are mostly related to inflammation, which can lead to malnutrition and osteoporosis. There are also gender differences such as hormone abnormalities and decreased male function. This article hopes to conduct a functional evaluation of a product that improves male nutrition and health care functions through animal experiments and in vitro cell experiments on bovine collagen and Cistanche deserticola compound peptides, verify its main functions, and improve the application of men’s health food in the elderly market. Design/Methodology/Approach – This article focuses on the design and investigation of the effect of this product on osteoporosis, male sperm motility and anti-inflammation. Therefore, the rat osteoporosis model, the cyclophosphamide testicular toxicity model, and the in vitro inflammatory cell experiment were used to produce corresponding experimental data. evaluate. Findings – Experiments have indeed verified that the compound peptide has the effects of preventing osteoporosis, promoting sperm motility, increasing testosterone levels and anti-inflammation. Research Implications – This study provides new ideas for the development of functional health foods for elderly men through the functional evaluation of complex peptides. It has certain significance for the selection of raw materials, formulation specifications and functional evaluation of men’s health products, and will also provide guidance for other scholars. Provide reference for subsequent research.
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Deng Yuhang,Liu Qingxiang,Liu Zhenni,Zhao Haijian,Zhou Weiyan,Zhang Chuanbao 대한진단검사의학회 2022 Annals of Laboratory Medicine Vol.42 No.5
Background: To identify candidate external quality assessment (EQA) materials for normetanephrine and metanephrine measurements, we assessed the commutability of eight processed human plasma samples. The agreement between routine assays and the candidate reference measurement procedure (cRMP) was also evaluated. Methods: Fifty-three clinical samples and eight processed plasma samples were prepared. The processed samples included pooled and individual plasma samples spiked with pure normetanephrine and metanephrine and non-spiked pooled and individual plasma samples. The clinical and processed samples were subjected to four routine isotope dilution tandem mass spectrometry assays and cRMP. Commutability was assessed based on two approaches recommended by the CLSI and International Federation of Clinical Chemistry (IFCC). Passing–Bablok regression and Bland–Altman analysis were used to evaluate the agreement between the routine assays and cRMP. Results: The commutability results of the CLSI approach were better than those of the IFCC approach. For the CLSI approach, spiked individual plasma samples and spiked high-concentration pooled plasma samples were commutable for all routine assays for both analytes. The non-spiked pooled plasma sample was commutable for two out of four routine assays for metanephrine and three out of four routine assays for normetanephrine. The agreement between the routine assays and the cRMP was satisfactory, except for one routine assay showing significant bias. Conclusions: High-concentration spiked pooled plasma samples and spiked individual plasma samples are candidate EQA materials for normetanephrine and metanephrine measurements.
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