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      • KCI등재후보

        EARLY CHILDHOOD EDUCATION FOR FILIPINO CHILDREN WITH INTELLECTUAL DISABILITIES: A COUNTRY REPORT

        ( Yolanda S. Quijano ) 대구대학교 한국특수교육문제연구소 2018 Asia-Pacific Journal of Intellectual Disabilities Vol.5 No.1

        In recent years, the Philippine Association for Intellectual Disabilities (PAFID) has forged partnership with the Early Childhood Care and Development (ECCD) Council to ensure that the Philippines focuses on building a strong foundation for development and learning of children including those with intellectual disabilities during the early years of zero (0) to four (4) and support the full range of health, nutrition, early education and social development for the child’s holistic development and warrant sustained interagency and multisectoral collaboration. The Early Childhood Education Program for Intellectual Disabilities in the Philippines is anchored on laws, namely, Republic Act No. 7277 (1992) or An Act Providing for the Rehabilitation, Self-Development and Self-Reliance of Disabled Persons and Their Integration, Republic Act 9288 or Newborn Screening Act of 2004, and Republic Act No. 10410 or the Early Years Act (EYA) of 2013. PAFID participated in ECCD programs and projects that integrate the concerns of children with intellectual disabilities. These include the National Child Development Center, Early Childhood Teacher Education Program, Development of System for Early Identification, Prevention, Referral and Intervention, Learning Resource Packages for Pre-Kindergarten and Standards and Guidelines for Center-Based Early Childhood Programs for 0 to 4 years old Filipino Children.

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        Impact of BRCA1/2 gene mutations on survival of patients with pancreatic cancer: A case-series analysis

        Ernesto Barzola Navarro,Emilio Vicente Lopez,Yolanda Quijano,Riccardo Caruso,Valentina Ferri,Hipolito Durand,Isabel Fabra Cabrera,Eduardo Diaz Reques,Benedetto Ielpo,Anastasiia Yuriyivna Glagoliev,Car 한국간담췌외과학회 2019 Annals of hepato-biliary-pancreatic surgery Vol.23 No.2

        BRCA gene mutations are found in up to 10% of pancreatic adenocarcinoma cases. We present a description of 4 cases along with a review of the current literature regarding pathogenesis, target treatment, response and survival rates in these types of malignancies. We describe four cases of pancreatic adenocarcinoma, in three of which the BRCA2 mutation was identified, in one - BRCA1 gene alteration. Two patients underwent surgery following the neoadjuvant treatment with Folfirinox and radiotherapy; in the first case, a distal pancreatectomy with splenectomy was performed and in the second one - the Whipple’s procedure. In both cases, a complete pathological response was reported. Other 2 patients were treated with Folfirinox after BRCA mutation identification and acceptable life expectancy was obtained. The association of pathologic complete response (PCR) with lower rates of local recurrence and better survival in patients with various types of adenocarcinomas is well known. Identification of such patients carrying BRCA mutations could provide an application of better personalized treatment. In some patients with pancreatic cancer, especially when there is clinical or demographic reason to suspect a genetic predisposition, a confirmation of the presence of BRCA mutations could provide an opportunity to use target treatment with beneficial outcomes regarding survival.

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