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      • Resource Allocation for Device-to-Device Communications Underlaying Cellular Networks

        Tao He,Xinquan Ye,Lieying Luo 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.5

        Device-to-Device (D2D) communications potentially can improve spectrum efficiency because of resource spatial reuse. There are two possibilities for D2D resource allocation: contention-based resource allocation and scheduling-based resource allocation. In this paper, these resource allocation schemes are analyzed. Then, we propose a scheduling-based resource allocation that has the advantage of low scheduling overhead in addition to providing a common design for under the in-network coverage and out-of-network coverage. Simulation results show that the proposed algorithm can increase system throughput by exploring spatial reuse gain and maintain good proportional fairness among D2D communication pairs.

      • Research on Exploration and Analysis of Supply Chain Flexibility Measure Index

        He Tao,Liang Zhidong,Ye Xinquan,Pang Jihong 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.11

        The supply chain risk assessment and management system has been developed, people still do not determine the way to overcome all these risks, especially for high impact, low probability events, such as SARS and the outbreak of foot-and-mouth disease, or a centralized terrorist attacks. This is because the lack of historical data to make all kinds of prediction and statistical tools fail. The modern supply chain were more vulnerable to risk, supply chain risk mainly comes from many aspects of the internal and external environment, the supply chain industry products background, upstream and downstream supply chain relationship, decision support. In this paper, the establishment of a complete supply chain model with variable structure, through the simulation method for quantitative observation of supply chain flexibility curve, and abstract to describe the elastic curve of a set of parameters; after the design of simulation experiment to observe the different supply chain structure parameters (inventory level, supply chain, supplier selection for number of sources) influence supply chain resilience curve.

      • Modeling and Parameter Estimation of Particle Swarm Optimization Algorithm for Smart Power Grid

        He Tao,Liang Zhidong,Ye Xinquan,Sun Shufeng,Pang Jihong 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.6

        This paper analysis the electric power communication network structure and performance requirements. To investigate the power communication backbone network and network power substation general way, and in electric power communication network delay, error rate, network bandwidth demand were analyzed. The for prevalent in electric power communication network is not a fully meshed network, explore artificially cobweb logic change principle and system method, artificial transform sheet mesh to the standard web, and making use of the cobweb, based on the characteristics of network fast routing. In order to better in the smart grid communication network using artificially cobweb routing algorithm, for the smart grid in the presence of irregular mesh network, this paper presents a kind of the mesh network into logical artificially cobweb network general standardization method. The principle of combination of label switching, this paper presents artificially cobweb source routing algorithm, expounds the artificially cobweb routing algorithm of label switching and label update mechanism, and artificially cobweb routing algorithm balancing routing method and routing method is described in detail.

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        Long non-coding RNA H19X promotes tumorigenesis and metastasis of colorectal cancer through regulating the miR-503-5p/KANK1 axis

        Yuan Zihan,Zhao Haizhou,Zhi Qiaoming,Wang Sentai,Liu Chao,Han Ye,Xu Zhihua,Liu Fei,Liu Xingyi,Zan Xinquan,Wang Qiang,Wan Daiwei 한국유전학회 2022 Genes & Genomics Vol.44 No.12

        Background: It has been well established that the long non-coding RNAs (lncRNAs) plays a critical role in tumor progression. However, the function of these transcripts and mechanisms responsible for their deregulation in colorectal cancer (CRC) remain to be investigated. Objective: To explore the potential effect and regulation mechanism of lncRNA H19X in colorectal cancer. Methods: We predicted and validated long non-coding RNA H19X from microarray data of colorectal cancer tissues. In addition, the biological behaviors of H19X and miR-503-5p on CRC were examined in vitro and in vivo, including MTT, colony formation assay, Hoechst33342 and transwell assay. The mRNA and protein levels of KN Motif and Ankyrin Repeat Domains 1 (KANK1) were analyzed by Quantitative real-time PCR (qRT-PCR), western blotting (WB) assay. Moreover, bioinformatics tools and dual-luciferase reporter assay were applied to demonstrate the relationship between KANK1 and miR-503-5p. Results: H19X was remarkably up-regulated in CRC tissues. Its expression related to tumor size (p = 0.041), lymph node metastasis (p = 0.037), distal metastasis (p = 0.028), advanced TNM stage (p = 0.034) and poor survival in CRC. H19X acted as an oncogenic lncRNA that induced CRC cell proliferation, invasion and metastasis. Through a number of functional studies, we found that H19X silencing inhibited the malignance phenotype of cancer cells through loss of miR-503-5p. Further studies demonstrated that miR-503-5p was involved in the progression of CRC by directly regulating the downstream target KANK1. Conclusion: Collectively, the findings of the present study indicate H19X/miR-503-5p/KANK1 axis has critical role in the progression of colorectal cancer, providing an effective prognostic indicator and promising target in treatment of colorectal cancer.

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