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      • KCI등재후보

        한국인 및 중국 한족 정신분열병 환자의 5-HT2A 수용체 유전자 -1438A/G 다형성

        이장호,이광철,이승부,오용인,최영근,조아랑,정주호,장환일 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.1

        Objectives : The purpose of the present study was to investigate the association between -1438A/G polymorphism of 5-HT2A receptor gene and schizophrenia in Korean and Han Chinese population. Methods : A sample of 184 Korean patients with schizophrenia and 96 Korean healthy normal controls and 96 Han Chinese patients with schizophrenia and 96 Han-Chinese healthy normal controls were genotyped for a single nucleotide polymorphism with in 5-HT2A receptor gene (promoter region, A-1438G) by Msp I Resthction Fragment Length Polymorphism (RFLP). Results : There was no difference in allelic frequencies and genotype frequencies of -1438A/G polymorphism between Korean schizophrenics and controls (p=0.13) and Han Chinese schizophrenics and controls (p=0.40). Also, -1438A/G Poly-morphism did not show ethnical difference between Korean and Han Chinese controls. The Scale for the Assessment of Negative Symptoms (SANS) scores showed no significant differences between genotypes of -1438A/G polymorphism in both of Korean and Han Chinese schizophrenics. Conclusion : These results suggest that -1438A/G polymorphism of the 5-HT2A receptor gene is not causally related to the development of schizophrenia in Korean and Han Chinese population, and there no ethnic difference between Korean and Han Chinese population.

      • Research on Parameter Optimization of Neural Network

        Guifang Wu,Yan Li,Yumin Ren,Hoonsung Kwak,Seyoung Jang 보안공학연구지원센터 2009 International Journal of Hybrid Information Techno Vol.2 No.1

        Based on researching parameter optimization method of neural network deeply, a new parameter optimization method is presented and applied to surface defect online inspection system of cold rolled strips. The method takes advantages of small-samples fully, and can get a group of neural network parameters which can mostly express the neural network under a certain specific condition. The method is advantageous for its simplicity, easy to maintain and fast, it can be applied to many fields too, such as iron-steel industry, medicine. Experiments showed that a best recognition effect by using the parameters for neural network which are achieved by the new parameter optimization method can be got among all the parameters optimized randomly for surface defect of cold rolled strips.

      • KCI등재

        A 2D/2D BiPO4/g-C3N4-B Z-type heterojunction for enhanced photocatalytic degradation of dye pollutants

        Zhao Hong-jian,Zhou Yan,Wu Ren-Jang,Han Zheng-bing,Li Xu,Yu Zhe 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.12

        A 2D/2D BiPO4/g-C3N4-B nano-sheet heterojunction photocatalyst was synthesized via a simple coprecipitation method at room temperature using glacial acetic acid as solvent, which showed excellent activity toward the degradation of rhodamine B (RhB). The heterojunction showed much higher efficiency of separation and transfer of photogenerated carriers compared to that of its constituents. Moreover, the spectral response range of BiPO4 was effectively broadened after the combination of g-C3N4-B and BiPO4. Consequently, a 97.3% degradation of RhB within 25 min by BiPO4/g-C3N4-B heterojunction photocatalyst under visible light irradiation was observed. The difference in work functions of BiPO4 and g-C3N4-B was evident from UPS characterization, which led to the bending of the energy band and the establishment of an internal electric field at the interface of the heterojunction. Therefore, the synthesized direct Z-type BiPO4/g-C3N4-B heterojunction enhanced the oxidation-reduction ability by promoting the effective separation of photogenerated carriers.

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