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- 저자 : Wooten, Marilyn (검색결과 2 건)
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Wooten, Marilyn,Shim, Jun Ho,Gorski, Waldemar WILEY-VCH Verlag 2010 Electroanalysis Vol.22 No.12
<P>The conventional gold electrodes were compared with recently published electrodes based on gold nanoparticles and gold nanostructured films as amperometric sensors for glucose in pH 7.40 phosphate buffer solutions. The conventional electrodes provided similar electroanalytical benefits while required much simpler and shorter preparation. It is recommended that the future reports on the development of electrochemical sensors based on metal nanoparticles/nanostructures include also the analytical figures of merit obtained at relevant conventional metal electrodes. The voltammetric studies indicated that, in contrast to phosphate buffers, the Tris buffers were not suitable for activation of gold surface toward the direct oxidation of glucose.</P>
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Biodegradable porous beads and their potential applications in regenerative medicine
Choi, Sung-Wook,Zhang, Yu,Yeh, Yi-Chun,Lake Wooten, A.,Xia, Younan The Royal Society of Chemistry 2012 Journal of materials chemistry Vol.22 No.23
<P>This article briefly reviews recent developments in the fabrication of biodegradable porous beads and their potential applications as cell carriers in regenerative medicine. The porous beads can be fabricated from natural (<I>e.g.</I>, chitosan, alginate, and collagen) and synthetic (<I>e.g.</I>, PLGA and PCL) polymers, as well as inorganic materials (<I>e.g.</I>, calcium phosphates). The highly porous structure facilitates not only cell seeding and migration but also transportation of nutrients/oxygen and metabolic wastes, leading to high levels of cell density and viability. The ability to directly inject a suspension of cell-loaded beads using a needle allows for delivery of target-specific cells to the site of defect or disease without surgical incision for tissue regeneration. Comparative studies of porous and non-porous beads clearly show the superiority of porous beads in terms of viability, proliferation, and differentiation of cells, as well as injectability of cell/bead constructs.</P> <P>Graphic Abstract</P><P>This feature article highlights recent progress in the fabrication of porous beads and their potential applications for regenerative medicine. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2jm16019f'> </P>
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