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- 저자 : Usman AZHAR (검색결과 3 건)
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Role of iron deficiency anemia in the propagation of beta thalssemia gene
Muhammad Usman,Moinuddin Moinuddin,Syed Azhar Ahmed 대한혈액학회 2011 Blood Research Vol.46 No.1
Background :The diagnostic criterion for beta thalassemia trait (BTT) is elevated Hb-A2 levels. Iron deficiency anemia (IDA) reduces the synthesis of Hb-A2, resulting in reduced Hb-A2 levels, so patients with co-pathological conditions BTT with IDA, may have a normal level of Hb-A2. Many socio-economic factors like unawareness, poor diagnostic facilities, and cost of molecular diagnosis (for screening purposes) result in interpretation of these subjects as normal. Methods :Venous blood samples from 200 unmarried females having a family history of thalassemia were collected, and basic hematological parameters, hemoglobin electrophoresis, and molecular analysis for beta thalassemia were done. Patients with IDA and patients with co-pathological conditions BTT and IDA were treated with oral iron. These subjects were then followed for a period of 20 weeks. Results :Of the 200 females, 34 were found to be anemic. Hemoglobin electrophoresis identified 16 of these patients as BTT. Molecular analysis of all patients confirmed this diagnosis, but identified 8 additional patients with BTT. Eight patients that were not detected with hemoglobin electrophoresis were found to have co-pathology of BTT with IDA. Conclusion :Patients with the co-pathological condition BTT with IDA may be interpreted as being normal, as they have normal Hb-A2 levels. These misdiagnosed subjects when marry with BTT have the potential to produce beta thalassemia major in offspring. This is one of the factors playing a major role in the propagation of beta thalassemia gene in Pakistani population, and become a serious hindrance for the thalassemia prevention program in Pakistan.
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SARWAR, Danish,SARWAR, Bilal,RAZ, Muhammad Asif,KHAN, Hadi Hassan,MUHAMMAD, Noor,AZHAR, Usman,ZAMAN, Nadeem uz,KASI, Mumraiz Khan Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.12
This empirical research is aimed at testing the relationship of the big five personality traits namely openness to experience, extraversion, consciousness, agreeableness, neuroticism, and risk aversion with the investment intention of individual investors belonging to Balochistan, Pakistan. The primary data is collected through a self-administered questionnaire (a structured form that consists of a series of closed-ended and open-ended questions) from a sample of 397 active individual investors belonging to different districts of the province. The data is empirically analyzed by applying the Partial Least Square (PLS) path modeling technique by using the estimation package available in Smart-PLS. The findings of this study suggest that all the variables are statistically significant with investors' investment intention with risk aversion as the strongest predictor. Moreover, openness to experience, extraversion, consciousness, agreeableness, and risk are significantly and positively related to an investor's investment intention, whereas neuroticism is negatively related to an investor's investment intention. The results extended by this study can be used by financial planners and investment bankers to channelize the available financial resources in diversified portfolios. The results will help financial planners to make available diverse investment alternatives for investors in Balochistan, thus catering to their unique needs. Academia must offer courses on contemporary finance paradigm based on behavioral finance to enable future business graduates to make wise financial decisions.
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Aneela SYED,Nagina GUL,Hadi Hassan KHAN,Muhammad DANISH,S.M. Nabeel Ul HAQ,Bilal SARWAR,Usman AZHAR,Wahab AHMED 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.1
Constructed upon Knowledge Management (KM) processes, the current study aims to investigate the interrelationship between Knowledge Sharing (KS) attitude among the faculty members and KM processes in higher education institutes (HEIs) in Pakistan along with the intervening role of subjective norms between KM processes and KS attitude. This research incorporated the theory of Planned Behavior (TPB) and the theory of Reasoned Action (TRA) to conceptualize the KS behavior by using a sample frame of 302 academic and administrative staff from research-based HEIs in Quetta, Pakistan. A questionnaire-based survey was conducted on permanent faculty members from different universities of Quetta, Pakistan. The finding of the study shows a positive attitude among the researchers. The study empirically examined the interface between KM processes and KS attitude and higher education performance while providing valuable insights into the prevailing literature by investigating the mediating role of subject norms. The impact of subjective norms on KS attitude and KM process indicates the importance and basic determinant in organizational premises and improvement of skills of faculty management in HEIs. The partial mediation also reveals the importance of subjective norms in the development of faculty members’ KM and KS attitude process.
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