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      • Predictors of Knowledge Level and Awareness towards Breast Cancer among Turkish Females

        Aydogan, Umit,Doganer, Yusuf C.,Kilbas, Zafer,Rohrer, James E.,Sari, Oktay,Usterme, Necibe,Yuksel, Servet,Akbulut, Halil,Balkan, Salih M.,Saglam, Kenan,Tufan, Turgut Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

        Background: Breast cancer (BC) is the most-common malignancy of women worldwide. Though there are differences among developed and developing countries, BC remains the most common cancer type of women in Turkey. Objective: This study aimed to identify the level of knowledge, awareness, and their potential predictors towards BC in Ankara, Turkey. Materials and Methods: The present descriptive study was conducted on 376 females attending a breast health outpatient clinic. A self-administered questionnaire was designed to evaluate knowledge level about BC and predictors effecting its level. Data analysis was performed using the chi-square test. A value of p<0.05 was considered statistically significant. Results: Mean age of the participants was $46.2{\pm}9.93$ (22-75). The majority (92.6 %) were married; 41.5% were educated less than nine years. Most of the women were housewives (82.7%) and, were living in an urban region (86.4%). Predictors of effecting responses to seven knowledge and awareness questions about BC varied from demographic features including older age groups, higher educational levels, being married, living in an urban area, being employee, smoking, having greater BMI to additional attributes associated breast health such as the increased number of births, applying for the purpose of control, positive family history of breast diseases, any diagnoses of breast diseases and performing BSE practice. Conclusions: It was determined that females in Turkey have better knowledge of BC than other developing countries even though it is not at the desired level. These findings revealed that females should be more informed about BC risk factors, prognosis and treatments by primary health-care providers to counteract the ascending burden of this disease.

      • Predictors Affecting Breast Self-Examination Practice among Turkish Women

        Doganer, Yusuf C.,Aydogan, Umit,Kilbas, Zafer,Rohrer, James E.,Sari, Oktay,Usterme, Necibe,Yuksel, Servet,Akbulut, Halil,Balkan, Salih M.,Saglam, Kenan,Tufan, Turgut Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

        Background: Breast cancer (BC) is the most common cancer among females in Turkey. Predictors affecting the breast self-examination (BSE) performance vary in developing countries. Objective: To determine the frequency of BSE performance and predictors of self-reported BSEs among women in the capital city of Turkey. Materials and Methods: This cross-sectional study was conducted on 376 Turkish women using a self-administered questionnaire covering socio-demographic variables and BSE-related features. Results: Of the participants, 78.7% (N=296) reported practicing BSE, whereas 9.5% (N=28) were implementing BSE regularly on a monthly basis, and only 5.7% (N=17) were performing BSE regularly within a week after each menstrual cycle. Multivariate logistic regression modeling revealed that BSE performance was more likely in younger age groups [20-39 years] (p=0.018, OR=3.215) and [40-49 years] (p=0.009, OR=3.162), women having a family history of breast disease (p=0.038, OR=2.028), and housewives (p=0.013, OR=0.353). Conclusions: Although it appears that the rates of BSE performers are high, the number of women conducting appropriate BSE on a regular time interval basis is lower than expected. Younger age groups, family history of breast diseases and not being employed were identified as significant predictors of practicing BSE appropriately. Older age and employment were risk factors for not performing BSE in this sample.

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        The effect of levothyroxine replacement therapy on lipid profi le and oxidative stress parameters in patients with subclinical hypothyroid

        Serkan Mutlu,Adem Parlak,Umit Aydogan,Aydogan Aydogdu,Bugra Soykut,Cemal Akay,Kenan Saglam,Abdullah Taslipinar 대한약학회 2021 Archives of Pharmacal Research Vol.44 No.8

        The purpose of this present study is to investigatethe levels of oxidative stress parameters in patientswith subclinical hypothyroidism (SH) and the effects oflevothyroxine (LT4) replacement therapy on these parametersand lipid profile. At the beginning of the study bloodsamples were collected from the patients in order to analyseoxidative stress parameters, lipid profile and biochemicalmarkers. After replacement therapy with LT4, inthe third month, same tests were performed again. At thebaseline superoxide dismutase (SOD) levels were found tobe higher in SH patients, compared to the euthyroid group. After LT4 therapy, statistically significant decreases inSOD and catalase levels and increase in HDL-C levelswere noticed. LT4 treatment was found to have positiveeffects on oxidative stress indicators and HDL-C levels.

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