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        Assessment of Bone Mineral Density of Patients with Spinocerebellar Ataxia Type 3

        Aline Maria Santos Farias,Simone Appenzeller,Marcondes C França Jr.,Alberto RM Martinez,Elba E Etchebehere,Thiago F Souza,Allan O Santos 대한파킨슨병및이상운동질환학회 2019 Journal Of Movement Disorders Vol.12 No.1

        Objective To evaluate whether less pulsatile levodopa therapy (LPT) can reduce the development of levodopa-induced dyskinesia (LID). Methods This is a retrospective cohort study of patients with Parkinson’s disease at the movement disorders clinic of Medstar Washington Hospital Center. The study was not blinded or randomized. Patients were seen between August 2002 and August 2018. During these years, we treated patients with less pulsatile (6 doses daily) levodopa treatment to reduce LID. Occurrence of LID was recorded. Results Ninety-five patients with Parkinson’s disease taking levodopa were divided into two groups: 1) patients who were initially managed on LPT or who switched from traditional therapy (TT) (n = 61) (mean disease duration: 7.7 ± 4.8 years, mean levodopa duration: 5.6 ± 4.5 years and mean observation time: 4.3 ± 3.4 years), and 2) patients on TT throughout the observation period or until they developed dyskinesia (n = 34) (mean disease duration: 8.3 ± 3.8 years, mean levodopa duration: 6.2 ± 4.2 years and mean observation time: 4.1 ± 3.4 years). Three of the 61 LPT patients developed dyskinesia during the observation period. One of the patients developed dyskinesia after being switched to pulsatile doses by another doctor. In the other two, dyskinesia was minimal. In contrast to this 4.9% cumulative incidence, dyskinesia occurred in 50% (17/34) of TT patients, an incidence similar to that in published data (p < 0.001). Conclusion Less pulsatile levodopa with 6 daily doses was associated with a low incidence of LID. Further study of this method of treatment is warranted.

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        Analysis of Polymeric Knitted Fabrics on Properties for Telecommunications Devices Application

        Marcos S. Aquino,Samanta M. Holanda,Thiago F. Santos,Moisés V. Melo,Nestor D. L. Junior,Idalmir S. Q. Júnior,Humberto D. Andrade 한국섬유공학회 2019 Fibers and polymers Vol.20 No.11

        The growing development of telecommunications, especially mobile telecommunications, has intensified researchinto microfiber antennas in the last years, since these have unique properties as well as a wide range of applications. Theresearch in the field of wearable technology is impelled by the demand for increasingly light and flexible devices, whereelectronic components are entirely embedded in their textile structures. The knitted fabrics have the necessary elasticity tocreate adaptive and sporty pieces, allowing high mobility and comfort to its users. The concept of textile antennas is based onmalleability and, for this reason, they can have great utility in applications where the stiffness of traditional antennas isconsidered a limitation, especially in military or biomedical garments. This study aims to determine the properties of thenatural and synthetic fibers knitted fabric for use in microwave devices, presenting the materials and methods used in theresearch to the prototyping and simulation of a microstrip antenna. Four knitted fabrics with different structures (Jersey andSimple Piquet) and fiber compositions (Cotton and Cotton with Polyamide) were selected. The determination of the electricalproperties was performed through the coaxial probe method to obtain the permittivity and tangent loss properties, and thedetermination of the physical properties according to the technical standards, where the textile properties (weight,dimensional stability, yarn count and tensile strength) of the analyzed samples were determined. The results were analyzedaccording to the proposed application and the CO_Piquet presented the lower loss tangent and better dimensional stability,the microstrip antenna was dimensioned to a frequency of 2.45 GHz according to the transmission line and resonant cavitymethod, and simulated in the HFSS where loss return, radiation diagrams and current density parameters was obtained.

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