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Sachi Higuchi,Seiichi Yoshida,Takeo Minematsu,Yutaka Hatano,Akifumi Notsu,Takamichi Ichinose 대한피부과학회 2023 Annals of Dermatology Vol.35 No.4
Background: In Japan, neonates have typically been bathed in a bathtub immediately after birth because bathing is a custom for cleansing impurities. However, dry technique has been introduced into many institutions since 2000. There is little scientific evidence on the ben- efit or harmfulness of either method to neonatal skin, and consequently, opinion remains split on which method is superior. Objective: The purpose of the present study was to determine whether bathing or the dry technique of cleaning is better in maintaining skin health in the early neonatal period. Methods: Transepidermal water loss (TEWL) and skin pH, considered an index of skin bar- rier function, were measured in each group. Tumor necrosis factor (TNF)-alpha and inter- leukin (IL)-6, which are inf lammatory cytokines released by keratinocytes, were measured by skin blotting. Results: TEWL and skin pH of neonates were lower with the dry technique than with bath- ing. The expression level of IL-6 and TNF-α in chest skin of neonates was higher with bath- ing than with the dry technique. Conclusion: These results suggest that the dry technique may maintain skin health better than bathing in the early neonatal period.