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      • Indoor Human Positioning Tracking Technique to Support High-Quality Life

        Toshinori Tsuboi,Takehiro Shiraishi,Nobuyoshi Komuro 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8

        Information Communication Technology (ICT) is expected to assist the activities of senior persons for raising their quality of life. This paper proposes an indoor human position tracking technique using UHF-band RFID(radio frequency identification). Seniors are liable to forget where they put items, such as a wallet or watch in the house. They could find the lost item if they could recall their movement history. The proposed technique is well satisfies this goal. This paper proposes a new simple positioning technique based on RFID. Simulations and experiments are conducted to confirm the basic performance of the proposed positioning algorithm.

      • Free Paper Session : Basic 2 & Obesity : Intestinal Mucosal Apoptosis By Ghrelin In Fasted Rats

        ( Jae Myung Park ),( Takashi Kakimoto ),( Tsukasa Kuroki ),( Ryosuke Shiraishi ),( Takehiro Fujise ),( Ryuichi Iwakiri ),( Kazuma Fujimoto ) 대한소화기학회 2007 SIDDS Vol.9 No.-

        Background/Aims: Ghrelin is mainly produced in the stomach and has several physiological functions. The aim of this study was to investigate whether ghrelin regulates apoptosis in the small intestinal mucosa of fasted rats. Methods: Intestinal mucosal apoptosis was evaluated as the percentage of fragmented DNA, villus height, TUNEL staining, and western blotting analysis of caspase-3 in 48-h-fasted rats. Crypt cell proliferation was evaluated by counting the number of BrdU-positive cells. Ghrelin was administered intraperitoneally at doses of 2.5, 25, and 250 ㎍/㎏ per 48 h by continuous infusion via an Alzet micro-osmotic pump or injections at 12 h intervals. Ghrelin was also infused in rats that underwent truncal vagotomy. The lowest dose of ghrelin (2.5 ㎍/㎏ per 48 h) was administered into the third cerebroventricle. Results: Ghrelin treatment attenuated the percentage of fragmented DNA in the small intestinal mucosa in 48-h-fasted rats in a dosedependent manner. Both continuous infusion and 12-hourly injections of ghrelin suppressed intestinal apoptosis to almost equal extent, This effect on apoptosis was not attenuated by truncal vagotomy. Cere-broventricular infusion of ghrelin also attenuated intestinal apoptosis. The antiapoptotic effect of ghrelin was confirmed by decreased TUNEL staining, recovery of the villus height, and decreased expression of caspase-3, BrdU uptake indicated that ghrelin enhanced cell proliferation in the intestinal crypt. Conclusions: Taken together, these data indicate that ghrelin enhanced intestinal growth with the suppression of small intestinal mucosal apoptosis in 48-h-fasted rats, suggesting that it controls intestinal function through the regulation of intestinal apoptosis.

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